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Surgery or Radiation (board transfer)

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From: MinnieChat

Here is a recent post from the Pituitary Tumor board that is part of the migration effort. If you have any comments, please share!
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From: wackyJAYNEdoe  (Original Message) Sent: 10/30/2005 12:25 AM
I have the option of surgery or radiation to remove the two tumors.  I was wonderinig if anyone could share their experiences on either method.  I am scared and wondering if there are risks of complications which could lead to worsing you physically or even death.
 
Thank you for all your help
~Susan~

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From: <NOBR>MSN NicknameMinnieChat</NOBR> Sent: 11/4/2005 5:19 PM
Susan,
Is this requst based on  primary therapy (first time tumor treatment-no surgery yet) or secondary therapy (reccurence)?
 
Minnie

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From: wackyJAYNEdoe Sent: 11/5/2005 9:58 PM
It is based on a first time tumor treatment(other than medicine)  I am having a hard time finding facts about either choice, and what could go wrong .
 
~Susan~

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From: <NOBR>MSN NicknameMinnieChat</NOBR> Sent: 11/5/2005 10:49 PM
I have some papers for you to look at:


 

I have seen alot of information that stereotactic radiosurgery can be used for prolactinomas, but the success rate is 25-30%. Here is a paper on Gamma Knife for Prolactinomas.
Out of 128 patients, 52% achieved good initial results, but out of those, 10% relapsed. So even in this series, the success was 42%.
Out of these patients, 77 were followed long term. Only 1 patient had increased tumor growth - therefore the tumor growth control was excellent.
 

Patients With Prolactinoma

Of the 19 patients with prolactinomas, normalization of serum PRL levels was documented in 11% (two patients). The mean time to remission was 20.5 months (range 18–23 months). No disease recurrence developed after remission. New hormonal deficiency was noted in 21% (four patients).


You can always get another opinion from a major pituitary center or a pituitarty endocrine specialist.

Good Luck Jane!

Minnie


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