>> Another option would be to use the DNS resolver (Bind, unbound, etc)
>> support to manipulate zone lookups.
> 
> But the OP wants a dedicated transport (for concurrency control and
> scheduling), not a change of destination IP, though in a multi-stage MTA
> setup that IP could point at a dedicated Postfix instance.

The OP mentioned mailjet(.com?) which is a service provider. It sounds
like all emails to domains hosted via *.outlook.com should be routed
via mailjet. That way concurrency control/scheduling is handed off to
them.

Another solution would be to implement a small daemon that is queried
via tcp_table. It could check a destination mx name via dns and if it
matches *.protection.outlook.com returns a mailjet server as nexthop.

https://www.postfix.org/tcp_table.5.html

Best regards
Gerald
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