http://news.bbc.co.uk/2/hi/health/6978384.stm



*'Human-animal' embryo green light*

Regulators have agreed in principle to allow human-animal embryos to be
created and used for research.

But scientists wanting to use hybrids will still need to make individual
applications, the Human Fertilisation and Embryology Authority said.

An HFEA consultation showed the public were "at ease" with the idea when
told it could pave the way for therapies for conditions such as Alzheimer's
disease.

Opponents have said many people would be "horrified" by such a move.

See how a human-animal embryo might be created


Scientists want to create hybrid embryos by merging human cells with animal
eggs in a bid to extract stem cells. The embryos would then be destroyed
within 14 days.


The cells form the basic building blocks of the body and have the potential
to become any tissue, making them essential for research.

At the moment, scientists have to rely on human eggs left over from
fertility treatment, but they are in short supply and are not always good
quality.

Two teams from Kings College London and Newcastle University have already
applied to the HFEA to use hybrid embryos.

It is now expected individual hearings for these two applications will be
held in November with other scientists expected to follow suit.

Reversed decision

Dr Lyle Armstrong, of Newcastle University, said: "It does seem a little
abhorrent at first analysis, but you have to understand we are using very,
very little information from the cow in order to do this reprogramming idea.


"It's not our intention to create any bizarre cow-human hybrid, we want to
use those cells to understand how to make human stem cells better."


Linacre Centre for Healthcare Ethics

Send us your comments

The HFEA decision comes amid government moves to lay down regulations
covering such research - the law governing embryo research is out of date
and does not cover the issue.

The government originally proposed banning the technique in a White Paper,
but reversed its decision this year in a bill which indicated ministers were
minded to allow hybrid embryos which were 99.9% human and 0.1% animal,
following a backlash by scientists and patient groups.

But the HFEA has carried out its own review ahead of parliament passing the
legislation so as not to hold back research.

The regulator can grant licences to scientists to pursue such research, but
will have to change its criteria if future rules contradicted its own
practices.

'Dehumanised'

Dr Helen Watt, from the Linacre Centre for Healthcare Ethics, said the
technique was "a further violation of the rights of the embryo".

Comment on Reproductive Ethics


"It is further dehumanised by the very method of its creation."

And Josephine Quintavalle, of the campaign group Comment on Reproductive
Ethics, said the HFEA was wrong to be pushing ahead with a decision which
should be left to parliament.

"Using hybrid embryos has never been acceptable - it offends the dignity of
humans and animals."


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