Penelitian begini, sekarang ini lazimnya dilakukan orang kafir
dan bukan oleh orang Islam yang memang rata-rata dungu-dungu
kayak anjing...
Orang Islam lebih rajin, sekarang ini bikin onar
kayak ketika ada kartun yang diterbitkan di Denemark itu, dan saling
berbunuhan seperti di Darfur, Iraq, Pakistan dll.
Islam itu, saya bilang dan saya ulang adalah laknat buat umat
manusia....
BBC NEWS
How HIV can sabotage human cells
Scientists have learned more details of the process which turns human
cells into factories for viruses such as HIV.
It is known that viruses are able to hijack the genetic machinery of
cells for their own ends.
Teams from Cambridge and Oxford Universities have witnessed the
process in action, and have identified the crucial role of key
elements.
The study, published in Nature, may eventually lead to new treatments
for HIV, and other infections.
Very many years of further research would be needed before
this research finding will benefit HIV-positive patients
Christopher Gadd
Genes provide cells with a code which they use to manufacture the
proteins needed to replicate themselves.
The latest study shows how viruses like HIV are able to undermine this
process.
As a result, cells misread the genetic code and instead of producing
healthy new cells, they begin to produce new copies of the virus.
Misreading
The process which the viruses employ is known as ribosomal
frameshifting. The ribosome is the structure within the cell where
protein synthesis takes place.
The genetic code contained in the DNA is read by ribosomes in chunks
of three individual components.
The researchers have shown that viruses such as HIV have signals that
force the ribosome to back up by just one component.
This is enough to produce a completely different sequence of genetic
chunks - and results in the cell beginning to produce proteins that
the virus can use to reproduce itself.
The researchers were able to capture images of frameshifting in
action using electron microscopy.
Researcher Dr Ian Brierley said the work might prove useful in
designing new ways to combat viruses such as HIV which deploy this
line of sabotage.
He said: "Other researchers have shown that inhibition of
frameshifting can block HIV replication; these new images improve our
understanding of frameshifting which might contribute to the design of
antiviral strategies."
Professor Julia Goodfellow, of the Biotechnology and Biological
Sciences Research Council, which part-funded the study, said: "The
treatments and therapies that we now take for granted are based on
decades of work by scientists furthering our understanding of natural
processes.
"The work to explore fundamental biology today is laying the
foundation for potential medical applications over the next 20 years."
Christopher Gadd, of the HIV information service NAM, said the latest
research had been carried out not on HIV, but on the virus that causes
the respiratory condition Sars.
He said: "This process may eventually become a target for research
into new HIV drugs.
"But after over 20 years of the epidemic, the 20 anti-HIV drugs
currently licensed only target three different sites in the virus's
life cycle.
"Although drugs targeting other parts of HIV's life cycle may be only
a few years away, very many years of further research would be needed
before this research finding will benefit HIV-positive patients, if at
all." Story from BBC NEWS:
http://news.bbc.co.uk/go/pr/fr/-/2/hi/health/4757363.stm
Published: 2006/05/10 23:02:06 GMT
© BBC MMVI
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