Pyramid is a great framework for building Web Applications in Python.  Your 
"project" isn't a web application - it's a suite of applications, some on 
the web, and would require lots of engineering talent.  Many of them could 
not be built in Pyramid or Erlang ( Smartphone apps, HTML/AJAX, etc ); 
you'd need to have a good understanding of server administration and 
scaling to properly handle the bandwidth as well.

That being said:
- Erlang is the best overall choice for VOIP, chat, and other high 
concurrency systems.
- Pyramid is the better choice of Erlang-vs-Pyramid for the web apps ( 
Enclyclopedia, dictionary, many of the html pages the house the rest ). 
 You'll be able to write and deploy much faster than Erlang.
- As things scale, you might find yourself having a Service Oriented 
Architecture with "internal APIs", written in Erlang, that your Python app 
talks to.  



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