Dear all,
I have a set of 200 methyltransferase protein structures. For protein - ligand
interactions study, I would like to classify the proteins in to different
groups. I have tried to classify the proteins based on sequence but it is not
satisfactory in view point of structures. Based on the previous suggestions I
have used the DALI server results like Z-score, RMS deviation for grouping. I
am ended up 35-40 groups for 200 structures. However, The results are not still
not convincing enough.
I have also tried, Pymol - superimpose and Chimera - structure based sequence
alignment, but both the program are crashing for 200 structures.
I will be thankful to you, if you suggest any alternative idea or online tools.
Thank you in advance.
With regardsAbdul Ajees
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