Christian Heimes added the comment:

New patch with typo fixes and update for recent modification in the 
make_flags() function.

The patch was motivated by use cases like Barry's issue with 3rd party software 
that accidentally messes with Python scripts like lsb_release. Your use case 
(testing) is valid but not the main focus here. Unmodified mode doesn't fit the 
bill either, Python can still import system wide packages or modifications from 
a venv.

Apropos venv, I need to check how the option is affected by venv.

Added file:

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