Hey,

I recently came across this app that might be of help: http://www.bemyeyes.org
I almost forgot about it, since I don’t have an iPhone,
but after watching “erbsen auf halb 6” recently, blindness is on the back of my 
mind.
Next time I want to watch that movie with my eyes closed.
But I digress.

I’m not sure how I would feel about tutoring, since I know next to nothing 
about bioinformatics.
I don’t even know what a microarray is or what you enrich with it. I know what 
DNA is and I can maybe fold a protein for you.
On the other hand, I’m looking for some part-time remote way to make some 
money, and I like teaching and technology.

Cheers,
Pepijn

On 19 Jan 2015, at 15:07, Guido Wesdorp <johnnydeb...@gmail.com> wrote:
> 
> Hallo allen,
> 
> Na een klein gevecht met de admin interface (waarbij ik dus verloren heb) heb 
> ik beloofd het onderstaand even voor iemand te posten.
> 
> Groeten,
> 
> Guido
> 
> Hi,
>  
> I am a visually impaired bioinformatics graduate student using microarray 
> data for my master’s thesis aimed at deciphering the mechanism by which the 
> yeast wild type can suppress the rise of free reactive oxygen species (ROS) 
> induced by caloric restriction (CR) thus extending lifespan but the Atg15 and 
> Erg6 knockout mutant cannot.
>  
> Since my remaining vision is very limited I need very high magnification.  
> But that makes my visual field very small.  Therefore I need somebody to 
> teach me how to use these programming environments, especially for microarray 
> analysis, next generation sequencing and constructing gene and pathway 
> interaction networks.  This is very difficult for me to figure out without 
> assistance because Zoomtext, my magnification and text to speech software, on 
> which I am depending because I am almost blind, has problems reading out 
> aloud many programming related websites to me.  And even those websites it 
> can read, it can only read sequentially from left to right and then from top 
> to bottom.  Unfortunately, this way of acquiring, finding, selecting and 
> processing new information and answering questions is too tiresome, 
> exhausting, ineffective and especially way too time consuming for graduating 
> with a PhD in bioinformatics before my funding runs out despite being 
> severely limited by my visual disability.  I would also need help with 
> writing a good literature review and applying the described techniques to my 
> own yeast Affymetrix microarray dataset because I cannot see well enough to 
> find all relevant publications on my own.
>  
> Some examples for specific tasks I urgently need help with are:
>  
> 1.    GO enrichment analysis, e.g. learning how to use the TopGo R package to 
> perform statistical analysis on GO enrichments.
>  
> 2.    Analyzing and comparing the three publically available microarray 
> datasets that can be accessed at:
> A.    http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE41860 
> <http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE41860>
> B.    http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38635 
> <http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38635>
> C.   http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9217 
> <http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE9217>
>  
> 3.    Learning how to use the Affymetrix microarray analysis software for the 
> Yeast 2 and Yeast S98 chip, which can be found 
> athttp://www.affymetrix.com/support/technical/libraryfilesmain.affx 
> <http://www.affymetrix.com/support/technical/libraryfilesmain.affx>
>  
> 4.    For Cytoscape I need somebody, who can teach me how to execute the 
> tutorials at the following links because due to my very limited vision field 
> I cannot see tutorial and program interface simultaneously.
> A.    
> http://opentutorials.cgl.ucsf.edu/index.php/Tutorial:Introduction_to_Cytoscape_3.1-part2#Importing_and_Exploring_Your_Data
>  
> <http://opentutorials.cgl.ucsf.edu/index.php/Tutorial:Introduction_to_Cytoscape_3.1-part2#Importing_and_Exploring_Your_Data>
> B.    
> http://opentutorials.cgl.ucsf.edu/index.php/Tutorial:Filtering_and_Editing_in_Cytoscape_3
>  
> <http://opentutorials.cgl.ucsf.edu/index.php/Tutorial:Filtering_and_Editing_in_Cytoscape_3>
> C.   
> http://cytoscape.org/manual/Cytoscape2_8Manual.html#Import%20Fixed-Format%20Network%20Files
>  
> <http://cytoscape.org/manual/Cytoscape2_8Manual.html#Import%20Fixed-Format%20Network%20Files>
> D.   http://wiki.cytoscape.org/Cytoscape_User_Manual/Network_Formats 
> <http://wiki.cytoscape.org/Cytoscape_User_Manual/Network_Formats>
>  
> Since I am legally blind the rehab agency is giving me money to pay tutors 
> for this purpose.  Could you please help me getting in touch regarding this 
> with anybody, who could potentially be interested in teaching me one on one 
> thus saving me time for acquiring new information and skills, which I need to 
> finish my thesis on time, so that I can remain eligible for funding to 
> continue in my bioinformatics PhD program despite being almost blind?  The 
> tutoring can be done remotely via TeamViewer 5 and Skype.  Hence, it does not 
> matter where my tutors are physically located.  Currently I have tutors in 
> Croatia and UK.  But since they both work full time jobs while working on 
> their PhD dissertation they only have very limited time to teach me online.  
> Could you therefore please forward this request for help to anybody, who 
> could potentially be interested or, who could connect me to somebody, who 
> might be, because my graduation and career depend on it? Who else would you 
> recommend me to contact regarding this?  Where else could I post this because 
> I am in urgent need for help?
>  
> Could you please contact me directly via email at thomas.f.ha...@gmail.com 
> <mailto:thomas.f.ha...@gmail.com> and/or Skype at tfh002 because my text to 
> speech software has problems to read out this website aloud to me? 
> 
> I thank you very much in advance for your thoughts, ideas, suggestions, 
> recommendations, advice, time, help, efforts and support. 
> 
> With very warm regards,
>  
> Thomas Hahn <>
> 1)    
> 
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