Thicker brain sections tied to spirituality, study  finds
(Reuters, January 31, 2014) 
For people at high risk of depression because of a family history,  
spirituality may offer some protection for the brain, a new study hints. 
Parts of the brain's outer layer, the cortex, were thicker in high-risk 
study  participants who said religion or spirituality was "important" to them 
versus  those who cared less about religion. 
"Our beliefs and our moods are reflected in our brain and with new imaging  
techniques we can begin to see this," Myrna Weissman told Reuters Health. 
"The  brain is an extraordinary organ. It not only controls, but is 
controlled by our  moods." 
Weissman, who worked on the new study, is a professor of psychiatry and  
epidemiology at Columbia University and chief of the Clinical-Genetic  
Epidemiology department at New York State Psychiatric institute. 
While the new study suggests a link between brain thickness and religiosity 
 or spirituality, it cannot say that thicker brain regions cause people to 
be  religious or spiritual, Weissman and her colleagues note in JAMA 
Psychiatry. 
It might hint, however, that religiosity can enhance the brain's resilience 
 against depression in a very physical way, they write. 
Previously, the researchers had found that people who said they were  
religious or spiritual were at lower risk of depression. They also found that  
people at higher risk for depression had thinning cortices, compared to those  
with lower depression risk. 
The cerebral cortex is the brain's outermost layer made of gray matter that 
 forms the organ's characteristic folds. Certain areas of the cortex are  
important hubs of neural activity for processes such as sensory perception,  
language and emotion. 
For the new study, the researchers twice asked 103 adults between the ages 
of  18 and 54 how important religion or spirituality was to them and how 
often they  attended religious services over a five-year period. 
In addition to being asked about spirituality, the participants' brains 
were  imaged once to see how thick their cortices were. 
All the participants were the children or grandchildren of people who  
participated in an earlier study about depression. Some had a family history of 
 
depression, so they were considered to be at high risk for the disorder. 
Others  with no history served as a comparison group. 
Overall, the researchers found that the importance of religion or  
spirituality to an individual - but not church attendance - was tied to having 
a  
thicker cortex. The link was strongest among those at high risk of  
depression. 
"What we're doing now is looking at the stability of it," Weissman said. 
Her team is taking more images of the participants' brains to see whether 
the  size of the cortex changes with their religiosity or spirituality. 
"This is a way of replicating and validating the findings," she said. "That 
 work is in process now." 
Dr. Dan Blazer, the J.P. Gibbons Professor of Psychiatry at Duke University 
 Medical Center in Durham, North Carolina, said the study is very 
interesting but  is still exploratory. 
"I think this tells us it's an area to look at," Blazer, who was not in
volved  in the new study, said. "It's an area of interest but we have to be  
careful." 
For example, he said there could be other areas of the brain linked to  
religion and spirituality. Also, spirituality may be a marker of something 
else,  such as socioeconomic status. 
Blazer added that it's an exciting time, because researchers are actively  
looking at links between the brain, religion and risk of depression. 
"We've seen this field move from a time when there were virtually no 
studies  done at all," he said. 
Weissman said the mind and body are intimately connected. 
"What this means therapeutically is hard to say," she added.  
____________________________________

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