How Spirituality Protects the Brain Against  Depression
Traci Pedersen ("Psych Central," January 19, 2014) 
Engaging in regular meditation or another spiritual practice is linked to a 
 thickening of the brain cortex, according to new research published in 
JAMA  Psychiatry. 
This discovery could lead to new insights as to why these activities help  
guard against depression, particularly in those who are genetically 
predisposed  to the mental health disorder. 
Major depression is characterized by a depressed mood for most of the day 
and  a loss of interest in normal activities and relationships. The disease 
affects  about 6.7% of the U.S. population over age 18, according to the 
National  Institute of Mental Health. 
This is the first published study investigating whether there is any 
physical  evidence in the brain linked to the protective effects of 
spirituality 
and  religion against depression. 
The research involved 103 adults at either high or low risk of depression,  
based on family history. Magnetic resonance imaging findings revealed 
thicker  cortices in those participants who placed a high importance on 
religion 
or  spirituality than those who did not. 
Furthermore, the relatively thicker cortex was found in exactly the same  
regions of the brain that had otherwise shown thinning in people at high risk 
 for depression. 
“The new study links this extremely large protective benefit of 
spirituality  or religion to previous studies which identified large expanses 
of 
cortical  thinning in specific regions of the brain in adult offspring of 
families 
at high  risk for major depression,” said Dr. Lisa Miller, professor and 
director of  Clinical Psychology and director of the Spirituality Mind Body 
Institute at  Teachers College, Columbia University. 
Prior research conducted by Miller and her team revealed a 90 percent  
decrease in major depression in adults who placed spirituality or religiosity 
at 
 high importance and whose parents suffered from depression. 
The findings showed that although regular attendance at church was not  
necessary, a strong personal importance placed on spirituality or religion was  
most protective against major depression in people who were at high 
familial  risk. 
Although more research is needed, the results suggest that spirituality or  
religion may protect against major depression by thickening the brain 
cortex and  counteracting the cortical thinning that would typically occur with 
major  depression.

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