Also, what is this 'random coil' region of an NMR spectrum? Are you 
referring to
areas of higher noise like near the water peak or between peaks versus a 100%
noise region of the spectrum?


> This would save NMR time and it would be sufficient for a model-free
> analysis if done carefully.  Remember that the RMSD value in the
> random coil region is higher than the empty parts of the spectrum, so
> don't forget to get some estimates by measuring in there.
>
> Regards,
>
> Edward
>




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