The random coil region is the area around 8 ppm (+/- 0.5 ppm) in the proton dimension where the protons of protein backbone amides located in coils, rather than ordered alpha or beta secondary structure, lye. Are your 1D experiments of proteins, RNA, DNA, or small molecules? I would guess that this effect will occur anywhere where there are many intense signals, such as a solvent signal.
Regards, Edward On Wed, Oct 15, 2008 at 9:42 PM, Tyler Reddy <[EMAIL PROTECTED]> wrote: > Also, what is this 'random coil' region of an NMR spectrum? Are you > referring to > areas of higher noise like near the water peak or between peaks versus a > 100% > noise region of the spectrum? > > >> This would save NMR time and it would be sufficient for a model-free >> analysis if done carefully. Remember that the RMSD value in the >> random coil region is higher than the empty parts of the spectrum, so >> don't forget to get some estimates by measuring in there. >> >> Regards, >> >> Edward >> > > > > _______________________________________________ relax (http://nmr-relax.com) This is the relax-users mailing list [email protected] To unsubscribe from this list, get a password reminder, or change your subscription options, visit the list information page at https://mail.gna.org/listinfo/relax-users
