Samtools (v1.2) merge doesn’t output any file of my two bam file and no message 
throwing out. It just hang there and reserved ~2.0g memory.  However, 0.1.18 
version finish the merging in ~2 mins.

The two sorted bam files are 449M and 448M in size.

v1.2
samtools merge  out.bam tmp/tmp.0000.bam tmp/tmp.0001.bam

Version: 0.1.18
samtools merge  out.bam tmp/tmp.0000.bam tmp/tmp.0001.bam

  real 2m26.713s
  user 2m20.100s
  sys 0m6.530s

Any insight or similar issue with error message from community?

Thanks,
Chienchi


From: Giuseppe Aprea <giuseppe.ap...@gmail.com<mailto:giuseppe.ap...@gmail.com>>
Date: Friday, February 6, 2015 at 10:13 AM
To: 
"samtools-help@lists.sourceforge.net<mailto:samtools-help@lists.sourceforge.net>"
 
<samtools-help@lists.sourceforge.net<mailto:samtools-help@lists.sourceforge.net>>
Subject: [Samtools-help] samtools merge

Hi all.

Is there any known limitation for bam merging?

I am trying to merge 4 sorted bam files with samtools (v 1.2) but I get the 
following error:


39656 Segmentation fault      (core dumped) samtools merge merging.bam 
*.sorted.realigned.nodup.sorted.bam


*.sorted.realigned.nodup.sorted.bam are 4 files with sizes: 6.1G, 6.2G, 3.9G 
and 4.0G


Any suggestion, please?


Thanks in advance,

Giuseppe
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