On 15 Jun 2015, at 17:46, Lo, Chien-Chi <chien...@lanl.gov> wrote: > Samtools (v1.2) merge doesn’t output any file of my two bam file and no > message throwing out. It just hang there and reserved ~2.0g memory. However, > 0.1.18 version finish the merging in ~2 mins. > > The two sorted bam files are 449M and 448M in size.
Do your bam files have many many headers? Samtools 1.2 merge could run for a very long time on such headers on some platforms [1]; thanks to Nathan Weeks, this problem has been fixed and the next samtools release should merge such files as fast as 0.1.x samtools. Giuseppe Aprea <giuseppe.ap...@gmail.com> wrote previously: > I am trying to merge 4 sorted bam files with samtools (v 1.2) but I get the > following error: > > 39656 Segmentation fault (core dumped) samtools merge merging.bam > *.sorted.realigned.nodup.sorted.bam Giuseppe's problem appears to be different, and it would indeed be useful to see a stack trace. John [1] https://github.com/samtools/samtools/pull/337 -- The Wellcome Trust Sanger Institute is operated by Genome Research Limited, a charity registered in England with number 1021457 and a company registered in England with number 2742969, whose registered office is 215 Euston Road, London, NW1 2BE. ------------------------------------------------------------------------------ _______________________________________________ Samtools-help mailing list Samtools-help@lists.sourceforge.net https://lists.sourceforge.net/lists/listinfo/samtools-help