On 22 Aug 2016, at 21:22, Thomas W. Blackwell <tbla...@umich.edu> wrote:
>
> I would try downloading the file and indexing your local copy.
That is indeed what the OP did:
>> $ bcftools index geno.TRA.bcf
>> Segmentation fault
> Unless I'm mistaken, nothing in the bcftools documentation
> indicates that it should work over an http: connection.
I don't think the documentation says anything in particular about this. But in
fact this works fine if you are using HTSlib's libcurl-based networking and
your web server allows you to do HTTP PUT. I'm not sure that this is
particularly useful for most people's existing local pipelines, though it may
turn out to be helpful for indexing data accessed via clouds.
John
--
The Wellcome Trust Sanger Institute is operated by Genome Research
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