On 10 Mar 2021, at 21:04, Remik Ziemlinski <rziemlin...@snapgene.com> wrote:
> The attached file worked with version 1.9, but is failing with 1.10 and 1.11. 
>  Is the file valid? Is there a regression after v1.9?
> [...]
> # output from version 1.9
> @HD VN:1.6 SO::unsorted
> @SQ    SN:reference    LN:5495

Your @HD line is delimited by spaces instead of tabs, which is invalid. The 
extra colon is not exactly helping either: it's syntactically valid and can be 
read in fine, but the value of ":unsorted" will be considered invalid by 
anything that actually looks at the SO value.

    John

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