Re: [monochrom] Increased glucose levels and blood pressure in IVF-conceived children

[Robert Schöftner]

peter hauser schrieb:

aus
"Nature Clinical Practice Endocrinology & Metabolism (2008) 4, 303-304"

Ceelen  et al. retrospectively investigated whether children conceived 
following in vitro fertilization (IVF) were at increased risk of developing 
cardiometabolic problems.

The researchers compared 225 children born after IVF with a control group of 
225 spontaneously conceived children matched for age and sex. All children 
(mean age at the time of follow-up 12.3 years, range 8–18 years) were born to 
parents with suboptimal fertility. All participants' blood pressure, skinfold 
thickness and body weight and height were recorded. A subset of 131 pubertal 
children from each group provided blood samples for measurement of indicators 
of insulin resistance.

Systolic and diastolic blood pressures, the sum of skin-fold thicknesses and 
fasting glucose levels were all significantly higher in children conceived 
following IVF than in controls. No significant differences were found between 
the two groups in fasting insulin concentrations, insulin resistance, or height 
and weight measurements. Multivariate regression analysis showed that blood 
pressure and fasting glucose levels remained significantly increased in 
IVF-conceived children after controlling for confounding factors.
  
sehr Interessant war die Sendung "Abenteuer Wissen" diese Woche zum 
Thema Epigenetik  und (auch) In 
Vitro Fertilisation. In TR gabs auch was zu dem Thema: 
http://www.heise.de/tr/Riskante-Befruchtung-im-Reagenzglas--/artikel/69552


sers
 Robert

[monochrom] Increased glucose levels and blood pressure in IVF-conceived children

[peter hauser]

aus
"Nature Clinical Practice Endocrinology & Metabolism (2008) 4, 303-304"

Ceelen  et al. retrospectively investigated whether children conceived 
following in vitro fertilization (IVF) were at increased risk of developing 
cardiometabolic problems.

The researchers compared 225 children born after IVF with a control group of 
225 spontaneously conceived children matched for age and sex. All children 
(mean age at the time of follow-up 12.3 years, range 8–18 years) were born to 
parents with suboptimal fertility. All participants' blood pressure, skinfold 
thickness and body weight and height were recorded. A subset of 131 pubertal 
children from each group provided blood samples for measurement of indicators 
of insulin resistance.

Systolic and diastolic blood pressures, the sum of skin-fold thicknesses and 
fasting glucose levels were all significantly higher in children conceived 
following IVF than in controls. No significant differences were found between 
the two groups in fasting insulin concentrations, insulin resistance, or height 
and weight measurements. Multivariate regression analysis showed that blood 
pressure and fasting glucose levels remained significantly increased in 
IVF-conceived children after controlling for confounding factors.
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