Age Question/Longevity Histio

2002-11-20 Thread Valerie Young
My heart just breaks to see the roll call of histio victims - and I know
there are many more to come.  Many of the names are familiar to me only
through this list, some I have known personally.

I was just wondering, if about 1 in 6 berners dies from histio, and if we
took the histio deaths out of the longevity statistics, I wonder what the
average age would be then?  That figure may make the importance of the
histio genetic study a little more obvious.

Valerie




Re: Age Question/Longevity Histio

2002-11-20 Thread Pat Long

Valerie,

I think you'll be very surprised! The average age at time of death for 
histio was 89.7 months, and the overall average was 84.43 months. So if we 
remove histio as part of the average age calculation, the average age at 
time of death - would go down! But if we find a way to prevent histio, then 
those dogs would live even longer, thereby increasing the average lifespan.

The cancer that really hurts us is lymphoma. Cancer, number of dogs, average 
age at time of death (in months) from the 2000 BMDCA health survey:

Malignant histio	43	 89.7
Lymphosarcoma		12	 78
Hemangiosarcoma		 7	113
Lymphoma		 7	 98.5
Osteosarcoma		 6	 93.3
Mast cell	 	 5	 81.7

Pat Long ( Luther)
Berwyn PA

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Re: Age Question/Longevity Histio

2002-11-20 Thread Ruth Reynolds
 The cancer that really hurts us is lymphoma.


It is my understanding that lymphoma is the most common cancer in dogs in
general.  I'm not sure if there is a heritable component to it or not.  It's
really hard to determine this when a dog dies of it and produces  the breed
average for it.  I don't know that it would really be determinable even if
the dog produced a higher than average incidence of it.  But in such a case
I'd be leaning in the direction of a heritable component to its occurence.

Ruth Reynolds




Re: Age Question/Longevity Histio

2002-11-20 Thread BernerFolk
In a message dated 11/20/2002 2:41:50 PM Eastern Standard Time, 
[EMAIL PROTECTED] writes:

 Cancer, number of dogs, average 
  age at time of death (in months) from the 2000 BMDCA health survey:
  
  Malignant histio 43   89.7
  Lymphosarcoma12   78
  Hemangiosarcoma   7  113
  Lymphoma  7   98.5
  Osteosarcoma  6   93.3
  Mast cell 5   81.7

The youngest average here is 6-1/2 yrs for lymphosarcoma... but we know we 
loose enough dogs young to bring the average to 7 yrs.  Pat does the curve 
tell us anything?  SOMETHING takes a sizeable number of our dogs young..
-Sherri Venditti




Re: Age Question/Longevity Histio

2002-11-20 Thread gwebara

On Wed, 20 Nov 2002 13:50:24 -0600 Ruth Reynolds [EMAIL PROTECTED]
writes:
 It is my understanding that lymphoma is the most common cancer in 
 dogs in
 general.  I'm not sure if there is a heritable component to it or 
 not.  It's
 really hard to determine this when a dog dies of it and produces  
 the breed
 average for it.  I don't know that it would really be determinable 
 even if
 the dog produced a higher than average incidence of it.  But in such 
 a case
 I'd be leaning in the direction of a heritable component to its 
 occurence

Ruth excuse my ignorance, but wasn't the study done by Dr. Padgett done
to determine the hereditability of cancer in Bernese and wasn't it
concluded that only histio and mast cell were hereditary?

Susan Ablon
Gweebarra BMD
Balch Springs, Tx
http://www.pageweb.com/gwebara




Re: Age Question/Longevity Histio

2002-11-20 Thread T Thompson


Hi Susan and all,



Susan wrote:


Ruth excuse my ignorance, but wasn't the study done by Dr. Padgett done
to determine the hereditability of cancer in Bernese and wasn't it
concluded that only histio and mast cell were hereditary?



** yes, that is what he has concluded so far.  however, he also said at the 
Symposium that he suspects hemangiosarcoma as being inherited, but does not 
yet have sufficient information

terry thompson
missoula, montana



Re: Age Question/Longevity Histio

2002-11-20 Thread Ruth Reynolds
 Ruth excuse my ignorance, but wasn't the study done by Dr. Padgett done to
determine the hereditability of cancer in Bernese and wasn't it concluded
that only histio and mast cell were hereditary


No, you'll have to forgive MY ignorance Susan.  That might have been a
conclusion that was drawn by the research team. I can't say.  Regardless, I
do not consider that or any other study to be a definitive study to
eliminate heredity as a factor in other cancers in our breed.  In fact, I
suspect in time we'll find out there are other cancers which are indeed
hereditary in our breed.

Ruth Reynolds




RE: Age Question/Longevity Histio

2002-11-20 Thread Pat Long Paul Dangel

I had some ISP problems, I'm playing catch-up here, forgive me if things
have already been answered.

Dr. Padgett and a group studied several types of cancer, and were able
to conclude at that time that only histio and mast cell definitely had a
hereditary basis in the breed. He is studying hemangiosarcoma and one
other type of cancer at the present time, and he is not yet ready to
make any hard and fast conclusions.

Pat Long ( Luther)
Berwyn PA