[ccp4bb] Lecturer/Senior Lecturer in AMR drug discovery at Newcastle University

2023-09-26 Thread Wyatt W. Yue
Dear all

There is an opening at Newcastle University for AMR drug discovery at
lecturer and senior lecturer level.

Target-based structure-guided drug design would play an integral part in
this endeavour, at the intersection of the University's leading strength in
microbiology and medicinal chemistry.

Further info can be found here:
Lecturer/ Senior Lecturer in Antimicrobial Drug Discovery (ncl.ac.uk)


Deadline 22 Nov 2023

Best wishes
Wyatt

*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Funded PhD position in Newcastle University (CRISPR tagging, protein complexes, cryo-EM)

2023-01-25 Thread Wyatt W. Yue
Dear all,
I would be grateful if you would please circulate the below PhD opportunity
to potential candidates in your network. Many thanks.
Wyatt Yue

Professor of Structural Biology

Biosciences Institute

Newcastle University NE2 4HH

Profile: wyattyue.github.io


*CRISPR-mediated tagging of endogenous proteins for structural mapping of
interactions*

A 4-year fully-funded PhD position is available in Wyatt Yue’s lab
 at Newcastle University (UK), under
the MoSMed CDT  programme.

The project builds on the lab's track record in studying metabolic enzyme
complexes, to explore the use of CRISPR gene editing in tagging endogenous
proteins for the isolation of multiprotein complexes, towards cryo-EM
structure determination and mapping of novel interactors.

Details of the project as well as instructions on how to apply can be found
through this link


The studentship is open to UK/EU/international applicants, with
deadline on *23:59
GMT Wednesday 15th Feb 2023*.


Enquiries on the project can be emailed to wyatt@newcastle.ac.uk



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Fwd: Postdoc position in crystallography-driven drug discovery, Yue Lab at Newcastle University

2022-11-11 Thread Wyatt W. Yue
A reminder of the below postdoc position in crystallography-driven drug
discovery at Newcastle University, with deadline in a week (*Friday 18th
November*)
Best wishes

*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io


-- Forwarded message -
From: Wyatt W. Yue 
Date: Tue, 1 Nov 2022 at 18:02
Subject: Postdoc position in crystallography-driven drug discovery, Yue Lab
at Newcastle University
To: , 


Dear all


The Yue lab in Newcastle University is currently advertising one postdoc
position in x-ray crystallography, funded for two years in the first
instance, open to all UK/EU/non-EU/international applicants.



https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate/861857001/



You will be a crystallographer working closely with an industry partner
towards small molecule discovery for a rare misfolding disease. You will
carry out crystallography-based fragment screening and biophysical
validation studies to guide compound design for a metabolic enzyme.



You can find out more about our group here:
https://www.staff.ncl.ac.uk/yuelab/



Any informal enquiries you can contact: wyatt@newcastle.ac.uk



Deadline: Friday 18 November 2022. We aim to hold interviews in the week of
28 Nov - 2 Dec 2022.


*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Postdoc position in crystallography-driven drug discovery, Yue Lab at Newcastle University

2022-11-01 Thread Wyatt W. Yue
Dear all


The Yue lab in Newcastle University is currently advertising one postdoc
position in x-ray crystallography, funded for two years in the first
instance, open to all UK/EU/non-EU/international applicants.



https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate/861857001/



You will be a crystallographer working closely with an industry partner
towards small molecule discovery for a rare misfolding disease. You will
carry out crystallography-based fragment screening and biophysical
validation studies to guide compound design for a metabolic enzyme.



You can find out more about our group here:
https://www.staff.ncl.ac.uk/yuelab/



Any informal enquiries you can contact: wyatt@newcastle.ac.uk



Deadline: Friday 18 November 2022. We aim to hold interviews in the week of
28 Nov - 2 Dec 2022.


*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Funded PhD position in Newcastle University (DEL screening, cryo EM and AI machine learning)

2022-02-15 Thread Wyatt W. Yue
Dear all, I would be grateful if you would please circulate this PhD
opportunity to potential candidates in your network. Many thanks.


*PhD project: Drug discovery at the interface of DEL screening, cryo EM and
AI machine learning*



A 4-year fully-funded PhD position is available in Wyatt Yue’s lab
 at Newcastle University, under the
MoSMed CDT  programme at Newcastle and
Durham (UK).



The project builds on the lab's track record in structural studies of human
metabolic enzymes, to discover chemical starting points for inhibitor
design, through working closely with medicinal (Mike Waring) and
computational (Daniel Cole) chemists at the university, as well as an AI
drug discovery company (Standigm Inc).



The student will receive training in protein biophysics and cryo-EM (Yue),
and have hands-on experience in DNA-encoded library screening (Waring),
protein-ligand simulations (Cole), and machine learning compound design
(Standigm).



Details of the project as well as instructions on how to apply can be found
here: NBDTP (ncl.ac.uk)




The studentship is open to UK/EU/international applicants, with
deadline on *23:59
GMT Wednesday 2nd March*.



Enquiries on the project can be emailed to wyatt@newcastle.ac.uk



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] PhD opportunity at the interface of structural biology and mitochondrial pathology (Newcastle University) - deadline 14th Jan 2022

2022-01-02 Thread Wyatt W. Yue
Want to research at the interface of structural biology and genetic
diseases?

Interested in studying the cell’s waste recycling system (autophagy)?

Looking for a PhD project combining crystallography, cryo-EM, interactome
and cell-based techniques?

There is a fully-funded 4-year PhD opportunity available in the Yue Lab
 and Rob Taylor’s group

at
Newcastle University, through the MRC-funded Dimen_DTP
 programme.

Open to UK/EU/international applicants – apply by the deadline 14 Jan 2022

www.findaphd.com/phds/projectdetails.aspx?PJID=138540


Best wishes

*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Fwd: 3 postdoc positions on structure-based drug discovery in the Yue lab at Newcastle University

2021-12-05 Thread Wyatt W. Yue
A reminder of the below 3 postdoc openings in the Yue lab at Newcastle
University
7 more days to apply
Deadline Monday 13 December

-- Forwarded message -
From: Wyatt W. Yue 
Date: Mon, 29 Nov 2021 at 11:10
Subject: 3 postdoc positions on structure-based drug discovery in the Yue
lab at Newcastle University
To: , 

Dear all,

The Yue Lab, recently relocated to Newcastle, is recruiting 3 postdoc
positions offering exciting opportunities in different flavours of
structural biology/drug discovery, interacting closely with clinicians,
industry, and patient groups.

All are two-year positions in the first instance,
UK/EU/non-EU/international applicants all welcome.

Deadline: *Monday 13 December*. We aim to fill these positions by Q1 2022.

https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate/711931801/ (job ID:
11461) You will drive a structure-based drug discovery project in an
academic setting, funded by LifeArc and Action Medical Research, working
closely with medicinal chemists in Oxford and clinical scientists in UCL
towards hit-to-lead inhibitor optimisation for a rare epileptic disorder.
(Skills: crystallography, SPR, activity assays, CETSA; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate-in-Structure-Based-Drug-Design/711711601/
(job ID: 11462) You will run an academic-industrial collaboration with
Bicycle Therapeutics, towards structural and biophysical characterisation
of bicyclic peptides in complex with novel therapeutic targets in
immune-metabolism/oncology. (Skills: different expression approaches,
crystallography, SPR; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate-in-AI-&-fragment-based-drug-discovery/743752301/
(job ID: 13927) You will lead an early-stage discovery project funded by a
patient foundation, towards small molecule therapy for Friedreich’s ataxia
targeting a multi-protein complex. You will work closely with an AI company
in hit finding, and run validation studies to guide compound design through
machine learning (Skills: ITC, SPR, cryo-EM & x-ray, activity assays).

You can find out more about our group here:
https://www.staff.ncl.ac.uk/yuelab/

Any informal enquiries you can contact: wyatt@newcastle.ac.uk





*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] 3 postdoc positions on structure-based drug discovery in the Yue lab at Newcastle University

2021-11-29 Thread Wyatt W. Yue
Dear all,

The Yue Lab, recently relocated to Newcastle, is recruiting 3 postdoc
positions offering exciting opportunities in different flavours of
structural biology/drug discovery, interacting closely with clinicians,
industry, and patient groups.

All are two-year positions in the first instance,
UK/EU/non-EU/international applicants all welcome.

Deadline: *Monday 13 December*. We aim to fill these positions by Q1 2022.



https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate/711931801/ (job ID:
11461) You will drive a structure-based drug discovery project in an
academic setting, funded by LifeArc and Action Medical Research, working
closely with medicinal chemists in Oxford and clinical scientists in UCL
towards hit-to-lead inhibitor optimisation for a rare epileptic disorder.
(Skills: crystallography, SPR, activity assays, CETSA; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-Associate-in-Structure-Based-Drug-Design/711711601/
(job ID: 11462) You will run an academic-industrial collaboration with
Bicycle Therapeutics, towards structural and biophysical characterisation
of bicyclic peptides in complex with novel therapeutic targets in
immune-metabolism/oncology. (Skills: different expression approaches,
crystallography, SPR; bit of cryo-EM)

https://jobs.ncl.ac.uk/job/Newcastle-Research-AssistantAssociate-in-AI-&-fragment-based-drug-discovery/743752301/
(job ID: 13927) You will lead an early-stage discovery project funded by a
patient foundation, towards small molecule therapy for Friedreich’s ataxia
targeting a multi-protein complex. You will work closely with an AI company
in hit finding, and run validation studies to guide compound design through
machine learning (Skills: ITC, SPR, cryo-EM & x-ray, activity assays).



You can find out more about our group here:
https://www.staff.ncl.ac.uk/yuelab/

Any informal enquiries you can contact: wyatt@newcastle.ac.uk





*Wyatt Yue*

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] Two postdoc positions in Newcastle University on structural biology & drug discovery

2021-09-16 Thread Wyatt W. Yue
Dear all


The Yue lab has recently moved to the Newcastle University Biosciences
Institute, and is now up and running! www.staff.ncl.ac.uk/yuelab/


We are currently recruiting two postdoc positions in structure-guided drug
discovery.

1.   Want to work on a hit-to-lead translational project in rare
metabolic disease, funded by LifeArc & Action Medical Research? Research
Associate - Rare Disease Drug Discovery (ncl.ac.uk)


2.   Want to work at the academia-pharma interface, in collaboration
with Bicycle Therapeutics, towards rational design of bicyclic
peptides? Research
Associate in Structure Based Drug Design (ncl.ac.uk)


Both positions (of two years initially) are ideally suited to
early/mid-stage structural biologists who are excited by a career in drug
discovery (with opportunities to write papers, apply for grants, and
disseminate data), and are driven to work in a team and collaborative
environment.


Closing date: 8th October 2021


Informal enquiries to wyatt@newcastle.ac.uk


Wyatt Yue

Professor of Structural Biology

Biosciences Institute

Faculty of Medical Sciences

Newcastle University NE2 4HH

Group: www.staff.ncl.ac.uk/yuelab/

Profile: wyattyue.github.io



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1

This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list 
hosted by www.jiscmail.ac.uk, terms & conditions are available at 
https://www.jiscmail.ac.uk/policyandsecurity/


[ccp4bb] X-ray/EM postdoc position in SGC Oxford, to study rare diseases at the academic-pharma interface

2019-04-15 Thread Wyatt W. Yue
Dear all,

I am writing to circulate a postdoc position currently available in my
group at SGC University of Oxford:



https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/140142-Postdoctoral-Research-Scientist---Structural-Biology-in-Metabolic-Diseases
(deadline *29th Apr, 12pm UK*)



Building on our glycogen research in the past few years (Bilyard et al
 2018 Nature, Froese et
al  2015 Hum Mol
Genet, Chaikuad et al  2011
PNAS), we are seeking a structural biologist (x-ray/EM) to determine the
molecular mechanism of glycogen biosynthesis, with a view to drug discovery
for the group of rare diseases known as glycogen storage disorders.



He/she will forge close interactions with medicinal chemists and cell
biologists at Pfizer rare disease research unit (Cambridge MA). This is
ideally suited for early/mid-stage researchers who are excited by a career
in drug discovery at the interface of academia and pharma (with
opportunities to write papers, apply for grants, and disseminate data).


Informal enquiries to: wyatt@sgc.ox.ac.uk

Visit our group page: *https://www.thesgc.org/groupprofile/9491
*



Assoc Prof Wyatt Yue
SGC University of Oxford
www.thesgc.org/wyatt



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1


[ccp4bb] Postdoc position in structural biology of metabolic enzymes & complexes, SGC University of Oxford

2019-02-17 Thread Wyatt W. Yue
Dear all,



We seek a post-doctoral scientist with strong background and track record
in structural biology (crystallography/EM), to drive an industry-funded
project studying glycogen metabolism and associated disorders.


https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/139434-Postdoctoral-Research-Scientist-%C2%96-Structural-Biology-in-Metabolic-Diseases


Closing date:  *noon GMT, 11th March 2019*


Informal enquiries to: wyatt@sgc.ox.ac.uk

Visit our group page: *https://www.thesgc.org/groupprofile/9491
*



Assoc Prof Wyatt Yue
SGC University of Oxford
www.thesgc.org/wyatt



To unsubscribe from the CCP4BB list, click the following link:
https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB=1


[ccp4bb] Research Technician (Structural biology) position at SGC, University of Oxford

2018-05-29 Thread Wyatt W. Yue
 Dear all,

We are advertising a research technician position in the Metabolism and
Organelle Biogenesis group at the SGC University of Oxford, which processes
a variety of human medically-relevant proteins/complexes in recombinant
expression systems, for structural and biophysical studies.

Closing date: Monday 11th Jun 2018, 12pm UK


Interested candidates please apply via University of Oxford job page:

*https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/134758-Laboratory-Technician---Protein-Structural-Biology
<https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/134758-Laboratory-Technician---Protein-Structural-Biology>*


Visit our SGC group page:

*http://www.thesgc.org/groupprofile/9491
<http://www.thesgc.org/groupprofile/9491>*


Informal inquiries to:

wyatt@sgc.ox.ac.uk

Follow us on Twitter:
https://twitter.com/YueLabSGC


-

Assoc Prof Wyatt W. Yue

Structural Genomics Consortium

Nuffield Department of Medicine

University of Oxford OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt


[ccp4bb] Research Technician (Structural biology) position at SGC, University of Oxford

2017-08-23 Thread Wyatt W. Yue
Dear all,

We are advertising a research technician position in the Metabolism and
Organelle Biogenesis group at SGC University of Oxford, which processes a
variety of human medically-relevant proteins in recombinant expression
systems, and purifies the proteins for structural and biophysical studies.

Closing date: Wednesday 6th Sept 2017, 12pm UK


Interested candidates please apply via University of Oxford job page that
is accessible from here:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/130724-Laboratory-Technician-Protein-Structural-Biology


Visit our SGC group page:

*http://www.thesgc.org/groupprofile/9491
<http://www.thesgc.org/groupprofile/9491>*


Informal inquiries to:

wyatt@sgc.ox.ac.uk



-

Assoc Prof Wyatt W. Yue

Structural Genomics Consortium

Nuffield Department of Medicine

University of Oxford OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt


[ccp4bb] Postdoc position at SGC Univ of Oxford, on structural biology of meganucleases

2017-07-08 Thread Wyatt W. Yue
Dear all

We are recruiting a Postdoctoral Scientist, with experience in structural
biology of protein-nucleic acid complexes, to join the research group led
by Associate Professor Wyatt Yue at the Structural Genomics Consortium
(SGC), University of Oxford.

In collaboration with Precision Biosciences Inc, the group is launching a
project, funded by a Wellcome Trust Pathfinder award, on structure-based
engineering of meganucleases for therapeutic genome editing in
trinucleotide repeat disorders.

You will hold a PhD (or be near completion) in protein biochemistry or
structural biology, have experience in purification, crystallization and
structure determination of protein-nucleic acid complexes, and be able to
work as part of a team interacting with industrial scientists. This is a
full-time post offered for a fixed-term of 18 months in the first instance.

Further particulars, including details on how to apply and links to further
information, can be accessed online:

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/129660-Postdoctoral-Research-Scientist-%E2%80%93-Metabolism-and-Organelle-Biogenesis-(Wellcome-Trust-Pathfinder)

Closing date: *12:00 noon (UK) on 13 July 2017 (Thursday next week)*

Informal enquiries can be made to wyatt@sgc.ox.ac.uk

Visit Wyatt Yue’s SGC home page: http://www.thesgc.org/wyatt


[ccp4bb] Reminder: Structural biologist in metabolic diseases, SGC University of Oxford

2017-04-06 Thread Wyatt W. Yue
Dear all,

A reminder of the below job opening at SGC University of Oxford.
We are looking for an enthusiastic structural biologist with experience in
drug discovery.
Deadline in a week's time (13th April 12pm GMT+1)

Wyatt Yue

On 15 March 2017 at 12:32, Wyatt W. Yue <yuewai...@gmail.com> wrote:

> Dear all
>
> We are recruiting a structural biologist at senior/postdoctoral level, to
> join the metabolic research team at the SGC University of Oxford, led by
> Assoc Prof Wyatt Yue.
>
> You will be part of a dynamic and focused team, elucidating the molecular
> mechanism and small molecule therapy for the causative gene products of
> common (e.g. diabetes, obesity, endocrinology) and rare (e.g. inborn errors
> of metabolism) disorders.
>
>
>- You have a PhD in structural biology/biochemistry
>- You have experience in structure-based drug discovery
>- You have interest in the field of metabolic diseases
>- You are a self-starter, team player and completer/finisher who
>enjoys a challenge
>
> Interested applicants please refer to job description and apply online via
> the page (Vacancy ID: 127848):
>
> https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/
> 127848-Structural-Biologist-in-Metabolic-and-Rare-Diseases
>
>
>
> Closing date: *12.00 midday (UK) on Thursday 13 April 2017*
>
>
> Informal enquiries to wyatt@sgc.ox.ac.uk
>
> Visit Wyatt Yue’s SGC home page: http://www.thesgc.org/wyatt
>


[ccp4bb] Structural biologist in metabolic diseases, SGC University of Oxford

2017-03-15 Thread Wyatt W. Yue
Dear all

We are recruiting a structural biologist at senior/postdoctoral level, to
join the metabolic research team at the SGC University of Oxford, led by
Assoc Prof Wyatt Yue.

You will be part of a dynamic and focused team, elucidating the molecular
mechanism and small molecule therapy for the causative gene products of
common (e.g. diabetes, obesity, endocrinology) and rare (e.g. inborn errors
of metabolism) disorders.


   - You have a PhD in structural biology/biochemistry
   - You have experience in structure-based drug discovery
   - You have interest in the field of metabolic diseases
   - You are a self-starter, team player and completer/finisher who enjoys
   a challenge

Interested applicants please refer to job description and apply online via
the page (Vacancy ID: 127848):

https://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/127848-Structural-Biologist-in-Metabolic-and-Rare-Diseases



Closing date: *12.00 midday (UK) on Thursday 13 April 2017*


Informal enquiries to wyatt@sgc.ox.ac.uk

Visit Wyatt Yue’s SGC home page: http://www.thesgc.org/wyatt


[ccp4bb] Research Technician (Structural biology) position at University of Oxford

2015-07-01 Thread Wyatt W. Yue
Dear all,

We are advertising a research technician position in the Metabolic and Rare
Diseases group at SGC University of Oxford, which processes a variety of
human medically-relevant proteins in recombinant expression systems, and
purifies the proteins for structural and biophysical studies.


Closing date: Wednesday 15th July 2015, 12pm GMT


Interested candidates please apply via University of Oxford job page that
is accessible here (vacation ID 118978):

http://www.thesgc.org/careers/oxford/sgc-oxford-laboratory-technician-%E2%80%93-protein-structural-biology


Visit the SGC Metabolic  Rare Diseases group page:

http://www.thesgc.org/science/mob


Informal inquiries to:

wyatt@sgc.ox.ac.uk

-

Assoc Prof Wyatt W. Yue

PI in Metabolic  Rare Diseases

Structural Genomics Consortium

Nuffield Department of Medicine

University of Oxford OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt


[ccp4bb] Deadline Reminder: Postdoc position in structural biology of multiprotein complexes, SGC University of Oxford

2015-03-09 Thread Wyatt W. Yue
Dear all,



*A reminder of the following application deadline (16th March, 12pm GMT):*


We seek a post-doctoral scientist with strong background in structural
biology and protein-protein interactions, to drive an industry-funded
project studying the molecular mechanism of iron-sulphur cluster assembly
and associated genetic disorders.


Please apply online:


http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/117257-Postdoctoral-Research-Scientist-Structural-Biology-in-Rare-Diseases


Closing date: Monday 16th March 2015, 12pm GMT


Visit the SGC Metabolic  Rare Diseases group page:
http://www.thesgc.org/science/mob


Informal enquiries to: wyatt@sgc.ox.ac.uk



-

Dr Wyatt W. Yue

Principal Investigator, Metabolic  Rare Diseases

Structural Genomics Consortium

University of Oxford

UK OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt


[ccp4bb] Postdoc position in structural biology of multiprotein complexes, SGC University of Oxford

2015-02-24 Thread Wyatt W. Yue
Dear all,



We seek a post-doctoral scientist with strong background in structural
biology and protein-protein interactions, to drive an industry-funded
project studying the molecular mechanism of iron-sulphur cluster assembly
and associated genetic disorders.


http://www.ndm.ox.ac.uk/current-job-vacancies/vacancy/117257-Postdoctoral-Research-Scientist-Structural-Biology-in-Rare-Diseases


Closing date: Monday 16th March 2015, 12pm GMT


Visit the SGC Metabolic  Rare Diseases group page:
http://www.thesgc.org/science/mob


Informal enquiries to: wyatt@sgc.ox.ac.uk



-

Dr Wyatt W. Yue

Principal Investigator, Metabolic  Rare Diseases

Structural Genomics Consortium

University of Oxford

UK OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt


Re: [ccp4bb] Two Postdoc positions at the University of Oxford, SGC

2013-02-06 Thread Wyatt W. Yue
Gentle reminder of the following openings at SGC Oxford (deadline 7th
February noon). Thanks.

On 14 January 2013 17:51, Wyatt W. Yue yuewai...@googlemail.com wrote:

 Dear all,

 We are seeking two post-doc scientists in the Metabolic  Rare Diseases
 group at the Structural Genomics Consortium (SGC), University of Oxford:

 1. *Protein crystallographer*, driving multiple gene-to-structure
 projects to understand inborn errors of metabolism:


 https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=106057

 2. Industry-funded *Protein biochemist/structural biologist*, working on
 mechanism and small molecule development for protein misfolding disorders:


 https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=106055


 The successful candidates will
 - benefit from the SGC high-throughput platform for structural/biochemical
 characterization
 - work closely with an established network of geneticists, clinicians and
 drug developers
 - have regular access to the nearby Diamond synchrotron for data collection

 Visit the SGC Metabolic  Rare Diseases group: http://www.thesgc.org/wyatt

 Informal enquiries to: wyatt@sgc.ox.ac.uk

 Application deadline:* Noon 7th Feb 2013 (GMT)*
 *
 *
 *
 *

 

 Dr Wyatt W. Yue

 Principal Investigator, Metabolic  Rare Diseases

 Structural Genomics Consortium

 University of Oxford

 UK OX3 7DQ

 +44 (0)1865 617757

 http://www.thesgc.org/wyatt



[ccp4bb] Two Postdoc positions at the University of Oxford, SGC

2013-01-14 Thread Wyatt W. Yue
Dear all,

We are seeking two post-doc scientists in the Metabolic  Rare Diseases
group at the Structural Genomics Consortium (SGC), University of Oxford:

1. *Protein crystallographer*, driving multiple gene-to-structure projects
to understand inborn errors of metabolism:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=106057

2. Industry-funded *Protein biochemist/structural biologist*, working on
mechanism and small molecule development for protein misfolding disorders:

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=106055


The successful candidates will
- benefit from the SGC high-throughput platform for structural/biochemical
characterization
- work closely with an established network of geneticists, clinicians and
drug developers
- have regular access to the nearby Diamond synchrotron for data collection

Visit the SGC Metabolic  Rare Diseases group: http://www.thesgc.org/wyatt

Informal enquiries to: wyatt@sgc.ox.ac.uk

Application deadline:* Noon 7th Feb 2013 (GMT)*
*
*
*
*



Dr Wyatt W. Yue

Principal Investigator, Metabolic  Rare Diseases

Structural Genomics Consortium

University of Oxford

UK OX3 7DQ

+44 (0)1865 617757

http://www.thesgc.org/wyatt