Re: [ccp4bb] Abraham Szöke

[Debanu Das]

Dear Bill,

So sorry to hear this news and the passing of another wonderful
scientist and contributor in our field. It was very interesting
reading your obituary. May his soul rest in peace.

I first heard about John and Abraham as a graduate student and later
on when I joined Sung-Hou for postdoc training. I was interested in
their holographic method for x-ray structure determination as I was
dealing with a case where I had density for the partial molecule from
molecular replacement and experimental structure factors for the
entire protein/DNA complex and was looking at ways to recover density
for the missing portion in addition to experimental phasing.

"Holographic methods in X-ray crystallography. IV. A fast algorithm
and its application to macromolecular crystallography"
http://scripts.iucr.org/cgi-bin/paper?S0108767395002315

Best,
Debanu
---
LinkedIn: www.linkedin.com/in/debanudas
Cal Alumni: cal.berkeley.edu/debanudas


On Sun, Jan 29, 2017 at 8:17 PM, William G. Scott  wrote:
> Dear Colleagues:
>
> Is is with great sadness that I report the recent passing of Abraham Szöke, a 
> friend, colleague, informal mentor, and an exceptionally intelligent and 
> energetic source of boundless intellectual enthusiasm.
>
> Abraham was a physicist at Livermore who helped to design nuclear weapons for 
> a living, but he had many other interests. One of these was X-ray 
> crystallography, and with his wife and collaborator Hanna Szöke, as well as 
> John Somoza, he developed an approach to crystallographic real-space 
> electron-density refinement and optimization, implemented in a program called 
> EDEN, that produces electron density maps with minimal model bias in a robust 
> manner. The source code, along with a brief explanation and extensive user's 
> manual, is freely available:
>
> https://code.google.com/archive/p/edencrystallography/
>
> https://github.com/wgscott/edencrystallography
>
> EDEN is written in C and is easy to compile on any unix platform. A fink 
> package for OS X is also available, as are packages for various linux 
> distributions.
>
> John and I first met Abraham and Hanna Szöke when we were graduate students 
> at Berkeley. A few years later, I had the opportunity to collaborate with 
> them and to put EDEN to the test. A single-particle version of EDEN was also 
> under development, for use with electron microscopy. Abraham had a wide 
> variety of interests in addition to electron density reconstruction, 
> including many novel ideas about the origin of life. He enjoyed a multitude 
> of fruitful and productive collaborations throughout a period most normal 
> people would consider retirement. He passed away on Thursday at age 87 from 
> an opportunistic infection while combatting lymphoma.
>
>
> William G. Scott
> Professor, Department of Chemistry and Biochemistry
> and The Center for the Molecular Biology of RNA
> University of California at Santa Cruz
> Santa Cruz, California 95064
> USA
>
> http://scottlab.ucsc.edu

Re: [ccp4bb] Abraham Szöke

[Napoleao Fonseca Valadares]

I'm really sad to hear that. Rest in peace. 

One of his articles, which has William as the first author, is very 
interesting, well-written, easy to read, and I use it to illustrate and open 
the mind of biochemistry students regarding several important topics. Works 
like a charm. 

RNA Catalysis, Thermodynamics and the Origin of Life 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187163/ 

- Mensagem original -

> De: "William G. Scott" <wgsc...@ucsc.edu>
> Para: CCP4BB@JISCMAIL.AC.UK
> Enviadas: Segunda-feira, 30 de Janeiro de 2017 2:17:10
> Assunto: [ccp4bb] Abraham Szöke

> Dear Colleagues:

> Is is with great sadness that I report the recent passing of Abraham
> Szöke, a friend, colleague, informal mentor, and an exceptionally
> intelligent and energetic source of boundless intellectual
> enthusiasm.

> Abraham was a physicist at Livermore who helped to design nuclear
> weapons for a living, but he had many other interests. One of these
> was X-ray crystallography, and with his wife and collaborator Hanna
> Szöke, as well as John Somoza, he developed an approach to
> crystallographic real-space electron-density refinement and
> optimization, implemented in a program called EDEN, that produces
> electron density maps with minimal model bias in a robust manner.
> The source code, along with a brief explanation and extensive user's
> manual, is freely available:

> https://code.google.com/archive/p/edencrystallography/

> https://github.com/wgscott/edencrystallography

> EDEN is written in C and is easy to compile on any unix platform. A
> fink package for OS X is also available, as are packages for various
> linux distributions.

> John and I first met Abraham and Hanna Szöke when we were graduate
> students at Berkeley. A few years later, I had the opportunity to
> collaborate with them and to put EDEN to the test. A single-particle
> version of EDEN was also under development, for use with electron
> microscopy. Abraham had a wide variety of interests in addition to
> electron density reconstruction, including many novel ideas about
> the origin of life. He enjoyed a multitude of fruitful and
> productive collaborations throughout a period most normal people
> would consider retirement. He passed away on Thursday at age 87 from
> an opportunistic infection while combatting lymphoma.

> William G. Scott
> Professor, Department of Chemistry and Biochemistry
> and The Center for the Molecular Biology of RNA
> University of California at Santa Cruz
> Santa Cruz, California 95064
> USA

> http://scottlab.ucsc.edu

[ccp4bb] Abraham Szöke

[William G. Scott]

Dear Colleagues:

Is is with great sadness that I report the recent passing of Abraham Szöke, a 
friend, colleague, informal mentor, and an exceptionally intelligent and 
energetic source of boundless intellectual enthusiasm.

Abraham was a physicist at Livermore who helped to design nuclear weapons for a 
living, but he had many other interests. One of these was X-ray 
crystallography, and with his wife and collaborator Hanna Szöke, as well as 
John Somoza, he developed an approach to crystallographic real-space 
electron-density refinement and optimization, implemented in a program called 
EDEN, that produces electron density maps with minimal model bias in a robust 
manner. The source code, along with a brief explanation and extensive user's 
manual, is freely available:

https://code.google.com/archive/p/edencrystallography/

https://github.com/wgscott/edencrystallography

EDEN is written in C and is easy to compile on any unix platform. A fink 
package for OS X is also available, as are packages for various linux 
distributions. 

John and I first met Abraham and Hanna Szöke when we were graduate students at 
Berkeley. A few years later, I had the opportunity to collaborate with them and 
to put EDEN to the test. A single-particle version of EDEN was also under 
development, for use with electron microscopy. Abraham had a wide variety of 
interests in addition to electron density reconstruction, including many novel 
ideas about the origin of life. He enjoyed a multitude of fruitful and 
productive collaborations throughout a period most normal people would consider 
retirement. He passed away on Thursday at age 87 from an opportunistic 
infection while combatting lymphoma.


William G. Scott
Professor, Department of Chemistry and Biochemistry
and The Center for the Molecular Biology of RNA
University of California at Santa Cruz
Santa Cruz, California 95064  
USA

http://scottlab.ucsc.edu