Re: Immunoregulin for Chelsea
Hi Nina, I'm paying $10 a dose for IR from my vet Do you remember where you got yours and what it cost? I friend of mine wants to start some of her felv+ kitties on IR and is fairly certain that she can get it from one of the vets that her rescue group works with, but I'd like to know where else we might be able to get it. Thanks, Deanne From: Nina [EMAIL PROTECTED] Reply-To: felvtalk@felineleukemia.org To: felvtalk@felineleukemia.org Subject: Re: Immunoregulin for Chelsea Date: Fri, 12 May 2006 22:34:01 -0700 Thanks Deanne, I'm archiving the info and sent a forward to Sally. She lost her sweet baby Chrissy this afternoon, but the other kitty in trouble seems to be improving. I sent her the IR I had in my fridge and I'll let you know what happens if she decides to try it. I'm hoping that the success that Cindy had with administering it subq is not a fluke and that it will work for other kitties that stress out at the vet's office. Maybe that would work for your less-than-cooperative guys when/if the need arises. Nina ACALA PET ISSUES wrote: Chelsea received 1/2 ml I-V injections of immunoregulin aprox every 4 days for about 3 1/2 weeks for a total of 6 doses. We're now cutting back to once a week injections for another 3 weeks, at which time we'll do blood work to determine how her anemia is doing. If she's in the normal range, we'll probably continue with once a month immunoregulin injections for a few more months. If Chelsea is still anemia, we'll stay on once a week immunoregulin for a while longer. Though she was diagnosed with severe, non to poorly regenerative anemia, she's clearly been making red blood cells which I don't believe would have happened without the IR treatments. Really as anemic as Chelsea was, I was doubtful that she would respond to the treatment at all but she seems to be doing very well and is certainly enjoying life. We were lucky, Chelsea is a good patient and is very sweet by nature. It isn't easy to give I-V injections to a cat due to their small veins and it certainly isn't particularly easy on the cat either. I have several other felv+ rescue kitties, a couple of which will not be good candidates for IR treatment when they become symptomatic due to their less-than-cooperative personalities. We'll continue to give Chelsea other immune supportive supplements in addition to Immunoregulin and will hope for her continual improvement. Thanks for all your help, Deanne
Immunoregulin for Chelsea
I wanted to thank everyone for the advise given last month regarding 12 month-old felv+ Chelsea who was suffering from severe anemia. She began responding to treatment fairly quickly and had noticeably improved within the first 2 weeks. Chelsea has now received 6 injections of immunoregulin and has regained her normal energy level and has pink gums again. I took your advise to heart and put her on Droxy and folic acid in addition to the Pet Tinic, Feline Immune Support and Interferon that she had been receiving. She's scheduled for 3 more injections of Immunoregulin to complete the recommended course of treatment. When she gets her last injection, I'll get blood work done again to determine her current hematocrit level. You may remember that it was extremely low - 9.6% when she last had blood drawn on April 15th. I don't know if Chelsea's turn around will be permanent, but she has had a very good month and I'm hopeful that she'll have many more to come. Thanks again, Deanne
Re: Immunoregulin for Chelsea
Chelsea received 1/2 ml I-V injections of immunoregulin aprox every 4 days for about 3 1/2 weeks for a total of 6 doses. We're now cutting back to once a week injections for another 3 weeks, at which time we'll do blood work to determine how her anemia is doing. If she's in the normal range, we'll probably continue with once a month immunoregulin injections for a few more months. If Chelsea is still anemia, we'll stay on once a week immunoregulin for a while longer. Though she was diagnosed with severe, non to poorly regenerative anemia, she's clearly been making red blood cells which I don't believe would have happened without the IR treatments. Really as anemic as Chelsea was, I was doubtful that she would respond to the treatment at all but she seems to be doing very well and is certainly enjoying life. We were lucky, Chelsea is a good patient and is very sweet by nature. It isn't easy to give I-V injections to a cat due to their small veins and it certainly isn't particularly easy on the cat either. I have several other felv+ rescue kitties, a couple of which will not be good candidates for IR treatment when they become symptomatic due to their less-than-cooperative personalities. We'll continue to give Chelsea other immune supportive supplements in addition to Immunoregulin and will hope for her continual improvement. Thanks for all your help, Deanne From: Nina [EMAIL PROTECTED] Reply-To: felvtalk@felineleukemia.org To: felvtalk@felineleukemia.org Subject: Re: Immunoregulin for Chelsea Date: Fri, 12 May 2006 13:21:33 -0700 Deanne, Thank you for posting about your success with Chelsea. I'm so pleased she's doing better!! I'd like to know the specifics of your protocol/dosage too. Is she getting the IR subq, or IV? A friend from the list that no longer posts (I'm sure most of you remember Sally from San Jose) is having problems of unknown origin with a couple of neg cats and I've been telling her about IR. Any info you could post would be greatly appreciated. Congratulations on Chelsea feeling better! Nina Susan Loesch wrote: How wonderful that Chelsea is doing better!! What is the course of treatment your vet has used for the immunoregulin? I have seen different ones. How far apart and what dosage? Am getting ready to start one of my girls on that - my vet said .2cc per day for 4 days, then .2cc per week for 4 weeks and then .2cc every four months. */ACALA PET ISSUES [EMAIL PROTECTED]/* wrote: I wanted to thank everyone for the advise given last month regarding 12 month-old felv+ Chelsea who was suffering from severe anemia. She began responding to treatment fairly quickly and had noticeably improved within the first 2 weeks. Chelsea has now received 6 injections of immunoregulin and has regained her normal energy level and has pink gums again. I took your advise to heart and put her on Droxy and folic acid in addition to the Pet Tinic, Feline Immune Support and Interferon that she had been receiving. She's scheduled for 3 more injections of Immunoregulin to complete the recommended course of treatment. When she gets her last injection, I'll get blood work done again to determine her current hematocrit level. You may remember that it was extremely low - 9.6% when she last had blood drawn on April 15th. I don't know if Chelsea's turn around will be permanent, but she has had a very good month and I'm hopeful that she'll have many more to come. Thanks again, Deanne
RE: Deanne: ImmunoRegulin for Chelsea?
Thanks Wendy. I've talked to others locally who have had their felv+ cats transfused, none of them said that they would do it again. They all seemed to think that it was a lot to put their cats though in order to buy a little more time. I tend to agree. I had hoped that we'd caught Chelsea's anemia in time for the immunoregulin to take effect. I still have a small amount of hope that she may turn around but the reality of what her blood work shows is hard to ignore. Chelsea had her blood drawn during an in-home visit by my vet Saturday. He was originally scheduled to visit to perform a euthanasia on another of my felv+ kitties MeCa who had developed lymphosarcoma. MeCa crossed over very peacefully, I hope for the same for Chelsea. Short of a miracle, I intend to make her last days as easy on her as possible and will continue with the immunoregulin, interferon and supplements. Thank you for your help and thoughts. Deanne From: wendy [EMAIL PROTECTED] Reply-To: felvtalk@felineleukemia.org To: felvtalk@felineleukemia.org Subject: Deanne: ImmunoRegulin for Chelsea? Date: Mon, 17 Apr 2006 07:10:05 -0700 (PDT) Deanne, Chelsea's blood work does not look good. If you can afford a transfusion, get one for Chelsea. It will buy you some time to see what is going on with her. 9.6 is very, very low. Time is of the essence. Good luck sweetie. I will keep you and Chelsea on my prayer list. Please let us know what happens. :) Wendy --- ACALA PET ISSUES [EMAIL PROTECTED] wrote: Chelsea got her first ImmunoRegulin shot yesterday. She also had blood drawn, after which she collapsed but later revived. She is still eating but is very weak. Below are the results of her bloodwork, it doesn't look good at all at this point. I'm giving her pet tinic, oral interferon and a product called Feline Immune System Support from Standard Process. The bloodwork showed no Hemobart, should I still ask for Doxycycline? My vet really isn't comfortable with Epogen, is there anything that I can tell him to change his mind? From: Online Manager [EMAIL PROTECTED] Subject: Marshfield Laboratory Results Date: Sat, 15 Apr 2006 22:31:56 -0500 --- Name:CHRISTMAN, FELINE CHELSEA (DEANNE) ID #: 3181189CA Species: FELINE Accn#: 82653812 Age: 12 months ApproximateDOB: 04/15/2005 Approximate Patient Location: SLENNGender: Female Veterinarian: RICHARD SLENN Breed: Domestic Short Hair FLAG - TEST - RESULTS -- UNITS --- REF RANGE -- Hemogram-CleVet (CLVCLT) Collection: 04/15/06 13:00 *L Red Blood Cell Count 1.41 x10^6/uL (5.80 - 11.00) *L Hemoglobin2.8 g/dL (8.6 - 16.0) *Result verified by repeat analysis. BLM 04/15/06 22:50 *L Hematocrit9.6 % (28.0 - 47.0) *Result verified by repeat analysis. BLM 04/15/06 22:50 H Mean Corpuscular Volume 68.0 fL(37.7 - 50.0) H Mean Corpuscular Hemoglob19.7 pg(12.3 - 17.2) L Mean Corpuscular Hgb Conc29.0 g/dL (31.1 - 36.0) Red Cell Distribution Wid19.6 % (17.0 - 24.0) Platelet Count * x10^3/uL (160 - 660) * PLT estimate from smear appears to be 100,000 - 175,000 /uL. White Blood Cell Count5.6 x10^3/uL (3.7 - 20.5) Seg. Neutrophil Absolute 1.96 x10^3/uL (1.30 - 15.70) Banded Neutrophil Absolut0.00 x10^3/uL (0.00 - 0.30) Lymphocyte Absolute #3.36 x10^3/uL (1.00 - 7.90) Act Lymphocyte Absolute #0.00 x10^3/uL (0.00 - 0.10) Monocyte Absolute # 0.17 x10^3/uL (0.00 - 1.00) Eosinophil Absolute #0.11 x10^3/uL (0.10 - 2.00) Basophil Absolute # 0.00 x10^3/uL (0.00 - 0.10) Other Absolute # 0.00 x10^3/uL (0.00 - 0.00) Blast Absolute # 0.00 x10^3/uL (0.00 - 0.00) Promyelocyte Absolute # 0.00 x10^3/uL (0.00 - 0.00) Myelocyte Absolute # 0.00 x10^3/uL (0.00 - 0.00) Metamyelocyte Absolute # 0.00 x10^3/uL (0.00 - 0.00) *Pathologist review. Result to follow in 1-2 days. 04/15/06 22:47 FINAL Report Marshfield Laboratories 1000 N. Oak Avenue, Marshfield WI 54449 --- Name:CHRISTMAN, FELINE CHELSEA (DEANNE) ID #: 3181189CA Species: FELINE Accn#: 82653812 Age
Re: ImmunoRegulin for Chelsea?
Chelsea got her first ImmunoRegulin shot yesterday. She also had blood drawn, after which she collapsed but later revived. She is still eating but is very weak. Below are the results of her bloodwork, it doesn't look good at all at this point. I'm giving her pet tinic, oral interferon and a product called Feline Immune System Support from Standard Process. The bloodwork showed no Hemobart, should I still ask for Doxycycline? My vet really isn't comfortable with Epogen, is there anything that I can tell him to change his mind? From: Online Manager [EMAIL PROTECTED] Subject: Marshfield Laboratory Results Date: Sat, 15 Apr 2006 22:31:56 -0500 --- Name:CHRISTMAN, FELINE CHELSEA (DEANNE) ID #: 3181189CA Species: FELINE Accn#: 82653812 Age: 12 months ApproximateDOB: 04/15/2005 Approximate Patient Location: SLENNGender: Female Veterinarian: RICHARD SLENN Breed: Domestic Short Hair FLAG - TEST - RESULTS -- UNITS --- REF RANGE -- Hemogram-CleVet (CLVCLT) Collection: 04/15/06 13:00 *L Red Blood Cell Count 1.41x10^6/uL (5.80 - 11.00) *L Hemoglobin2.8g/dL (8.6 - 16.0) *Result verified by repeat analysis. BLM 04/15/06 22:50 *L Hematocrit9.6% (28.0 - 47.0) *Result verified by repeat analysis. BLM 04/15/06 22:50 H Mean Corpuscular Volume 68.0fL(37.7 - 50.0) H Mean Corpuscular Hemoglob19.7pg(12.3 - 17.2) L Mean Corpuscular Hgb Conc29.0g/dL (31.1 - 36.0) Red Cell Distribution Wid19.6% (17.0 - 24.0) Platelet Count *x10^3/uL (160 - 660) * PLT estimate from smear appears to be 100,000 - 175,000 /uL. White Blood Cell Count5.6x10^3/uL (3.7 - 20.5) Seg. Neutrophil Absolute 1.96x10^3/uL (1.30 - 15.70) Banded Neutrophil Absolut0.00x10^3/uL (0.00 - 0.30) Lymphocyte Absolute #3.36x10^3/uL (1.00 - 7.90) Act Lymphocyte Absolute #0.00x10^3/uL (0.00 - 0.10) Monocyte Absolute # 0.17x10^3/uL (0.00 - 1.00) Eosinophil Absolute #0.11x10^3/uL (0.10 - 2.00) Basophil Absolute # 0.00x10^3/uL (0.00 - 0.10) Other Absolute # 0.00x10^3/uL (0.00 - 0.00) Blast Absolute # 0.00x10^3/uL (0.00 - 0.00) Promyelocyte Absolute # 0.00x10^3/uL (0.00 - 0.00) Myelocyte Absolute # 0.00x10^3/uL (0.00 - 0.00) Metamyelocyte Absolute # 0.00x10^3/uL (0.00 - 0.00) *Pathologist review. Result to follow in 1-2 days. 04/15/06 22:47 FINAL Report Marshfield Laboratories 1000 N. Oak Avenue, Marshfield WI 54449 --- Name:CHRISTMAN, FELINE CHELSEA (DEANNE) ID #: 3181189CA Species: FELINE Accn#: 82653812 Age: 12 months ApproximateDOB: 04/15/2005 Approximate Patient Location: SLENNGender: Female --- FLAG - TEST - RESULTS -- UNITS --- REF RANGE -- Differential-CleVet (CLVDIF) Collection: 04/15/06 13:00 Segmented Neutrophils 35% Lymphocytes60% Monocytes 3% Eosinophils 2% Polychromatophilia 1+ *H Nucleated Red Blood Cells 6/100WBC (0 - 0) No Mycoplasma haemofelis (formerly Hemobartonella felis) seen. LJM 04/15/06 23:30 *RBC agglutination may falsely decrease RBC number and increase MCV and MCH. RBC appear agglutinated. From: Belinda [EMAIL PROTECTED] Reply-To: felvtalk@felineleukemia.org To: felvtalk@felineleukemia.org Subject: Re: ImmunoRegulin for Chelsea? Date: Fri, 14 Apr 2006 17:00:06 -0700 First thing is to determine what is causing the anemia, giving doxy even when hemobart isn't found is a good idea, hemo is VERY hard to detect and the doxy will almost always take care of it and won't hurt Chelsea if she doesn't have hemo but will save her life if she does. Blood transfusions, and epogen depending onwhat is causing the anemia can really help. Also vitamin B complex and folic acid are needed to build blood. Prednisolone can help if it is similar to what Bailey has. --
ImmunoRegulin for Chelsea?
Hi, Any advise would be appreciated greatly. One of my 11 month old felv+ cats - Chelsea - who has been on a course of clavamox until a couple of days ago for a slight fever and lethargy has just developed very pale gums. They weren't pale 2 weeks ago when she last saw the vet. I know that pale gums are indicative of anemia. I'm trying to convince a vet to try Immunoregulin. Has anyone had much success with this therapy? Chelsea already gets interferon orally. Thanks, Deanne
Re: ImmunoRegulin for Chelsea?
Thanks Nina, I've got a vet appt for Chelsea on Saturday. I'll have them check for Hemobartinella. She didn't have pale gums two weeks ago when she saw a vet for her fever/lethargy. She still has a bounce in her step so I hope that whatever may be causing this, we'll have time to treat it. Deanne From: Nina [EMAIL PROTECTED] Reply-To: felvtalk@felineleukemia.org To: felvtalk@felineleukemia.org Subject: Re: ImmunoRegulin for Chelsea? Date: Thu, 13 Apr 2006 15:45:38 -0700 Deanne, Do you know what the cause of the anemia is? Did they do any other tests to try to determine why she's anemic, or did they just prescribe the Clavamox to see if it helped? When my Grace developed anemic symptoms, she was put on Clavamox, (or maybe it was Amoxi), at first too. It helped a little, for a little while, but she kept getting weaker. I found a specialty clinic and an Internist that ran several other tests, including one for blood parasites, (Hemobartinella). Even though the test was neg, we put Grace on Doxycycline, (a broader spectrum abx that would help if it was Hemobart). It did help her recover, I guess we'll never really know why. I haven't tried IR, but I've heard really good things from others on the list about it. It sometimes gets to the point where trying something unconventional is worth the risk, when doing nothing is not an option. Prayers that Chelsea turns around quickly. Nina ACALA PET ISSUES wrote: Hi, Any advise would be appreciated greatly. One of my 11 month old felv+ cats - Chelsea - who has been on a course of clavamox until a couple of days ago for a slight fever and lethargy has just developed very pale gums. They weren't pale 2 weeks ago when she last saw the vet. I know that pale gums are indicative of anemia. I'm trying to convince a vet to try Immunoregulin. Has anyone had much success with this therapy? Chelsea already gets interferon orally. Thanks, Deanne
