[Freesurfer] Qdec - generate stats data table

2012-03-22 Thread Ahmed, F, Me fah...@sun.ac.za
Hello,

I was running the tutorial on Qdec, when I went to generate stats data, it 
started running fine, and then I got the following error message:


aparcstats2table --hemi rh --parc aparc.a2005s --meas area --tablefile 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/qdec/stats_tables//rh.aparc.a2005s.area.stats.dat
 --subjects 140 049 141 084 021 093 080 091 040 017 138 106 108 092 124 129 103 
130 039 123 095 067 004 133 097 073 149 045 136 144 032 131 145 111 102 074 114 
008 128 099
Number of subjects : 40
Building the table..
ERROR: cannot find 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/140/stats/rh.aparc.a2005s.stats
Use --skip flag if you want to continue in such cases

--
aparcstats2table --hemi rh --parc aparc.a2005s --meas volume --tablefile 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/qdec/stats_tables//rh.aparc.a2005s.volume.stats.dat
 --subjects 140 049 141 084 021 093 080 091 040 017 138 106 108 092 124 129 103 
130 039 123 095 067 004 133 097 073 149 045 136 144 032 131 145 111 102 074 114 
008 128 099
Number of subjects : 40
Building the table..
ERROR: cannot find 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/140/stats/rh.aparc.a2005s.stats
Use --skip flag if you want to continue in such cases

--
aparcstats2table --hemi rh --parc aparc.a2005s --meas thickness --tablefile 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/qdec/stats_tables//rh.aparc.a2005s.thickness.stats.dat
 --subjects 140 049 141 084 021 093 080 091 040 017 138 106 108 092 124 129 103 
130 039 123 095 067 004 133 097 073 149 045 136 144 032 131 145 111 102 074 114 
008 128 099
Number of subjects : 40
Building the table..
ERROR: cannot find 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/140/stats/rh.aparc.a2005s.stats
Use --skip flag if you want to continue in such cases

--
aparcstats2table --hemi rh --parc aparc.a2005s --meas meancurv --tablefile 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/qdec/stats_tables//rh.aparc.a2005s.meancurv.stats.dat
 --subjects 140 049 141 084 021 093 080 091 040 017 138 106 108 092 124 129 103 
130 039 123 095 067 004 133 097 073 149 045 136 144 032 131 145 111 102 074 114 
008 128 099
Number of subjects : 40
Building the table..
ERROR: cannot find 
/mnt/hgfs/VBM/freesurfer_EONCS/EONCS/buckner_data/tutorial_subjs/140/stats/rh.aparc.a2005s.stats
Use --skip flag if you want to continue in such cases
Completed creation of aseg and aparc stats data tables.

Is this the same problem as before, where I might have an older bundle of data 
that doesn't contain these certain files? Is there a way I can recreate them 
and continue running the tutorial?

Thanks,
Fatima



  
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[Freesurfer] editing pial surface

2012-03-22 Thread Richter, Julia
Hi freesurfer experts,

I am trying to correct the pial surfaces of my data. I was able to remove 
voxels with the right button of my mouse, but unfortunately, it didn't work out 
to add voxels. Can somebody please help me with that? Do I need a middle button 
on the mouse for it?

Attached you may find a slice of the brain data. The red line (indicating the 
pial surface) and green line (indicating the grey matter/white matter boundary) 
cross, which should not happen in my opinion. Is there any possibility to 
change the lines so that they don't cross anymore?

Cheers, Julia



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[Freesurfer] Robust register

2012-03-22 Thread Ed Gronenschild
Hi,

I would like to use mri_robust_register to co-register
b-volumes to the reference b0-volume in a DTI dataset.
The documentation informs that it is not quite suitable
in case of large intensity differences which apply to
my case. How to proceed? Is a dev version available
for this purpose?

Cheers,
Ed
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Re: [Freesurfer] mkheadsurf and smseghead

2012-03-22 Thread Bruce Fischl
Hi Will

Doug is out of email contact until next week, and I suspect he's the best 
one to help you. If you haven't heard by mid week can you repost?

cheers
Bruce
On Thu, 22 
Mar 2012, Will Woods wrote:

 Hi,

 In my previous lab, which I no longer have access to, we ran
 mkheadsurf as part of postprocessing, and it generated smseghead
 files. The latest version of Freesurfer which I recently downloaded
 (with mkheadsurf version v 1.8 2011/03/02 20:16:39 nicks Exp) does not
 generate these files - and moreover the smheadsurf environment
 variable (which defaults to 'smseghead') in the mkheadsurf script does
 not appear to be used for anything in that script. Have I forgotten to
 do something in the earlier processing stages, or have things changed?

 Will
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Re: [Freesurfer] editing pial surface

2012-03-22 Thread Bruce Fischl
Hi Julia

it's really hard to tell from just this image. If the problem is the 
skull strip removing voxels you can use the clone tool to paint them 
back in from another volume like the T1.mgz. Are you sure it's not dura or 
pial vessels? Where in the brain do you mean?

cheers
Bruce

On Thu, 22 Mar 2012, Richter, 
Julia wrote:

 Sorry, this time with attachment :).

 Hi freesurfer experts,

 I am trying to correct the pial surfaces of my data. I was able to remove 
 voxels with the right button of my mouse, but unfortunately, it didn't work 
 out to add voxels. Can somebody please help me with that? Do I need a middle 
 button on the mouse for it?

 Attached you may find a slice of the brain data. The red line (indicating the 
 pial surface) and green line (indicating the grey matter/white matter 
 boundary) cross, which should not happen in my opinion. Is there any 
 possibility to change the lines so that they don't cross anymore?

 Cheers, Julia



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Re: [Freesurfer] mkheadsurf and smseghead

2012-03-22 Thread dgw
Hi Will,

I noticed this as well. I don't know Doug's thinking, but I suspect it 
was just to avoid generating lots of files. The new script overwrites 
the lh.seghead, when smoothing. I would just update your script to use 
lh.seghead instead of lh.smseghead.

HTH
D

Will Woods wrote:
 Hi,
 
 In my previous lab, which I no longer have access to, we ran
 mkheadsurf as part of postprocessing, and it generated smseghead
 files. The latest version of Freesurfer which I recently downloaded
 (with mkheadsurf version v 1.8 2011/03/02 20:16:39 nicks Exp) does not
 generate these files - and moreover the smheadsurf environment
 variable (which defaults to 'smseghead') in the mkheadsurf script does
 not appear to be used for anything in that script. Have I forgotten to
 do something in the earlier processing stages, or have things changed?
 
 Will
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Re: [Freesurfer] editing pial surface

2012-03-22 Thread Louis Nicholas Vinke
Hi Julia,
Are you editing on a Mac?
-Louis

On Thu, 22 Mar 2012, Richter, Julia wrote:

 Hi freesurfer experts,

 I am trying to correct the pial surfaces of my data. I was able to remove 
 voxels with the right button of my mouse, but unfortunately, it didn't work 
 out to add voxels. Can somebody please help me with that? Do I need a middle 
 button on the mouse for it?

 Attached you may find a slice of the brain data. The red line (indicating the 
 pial surface) and green line (indicating the grey matter/white matter 
 boundary) cross, which should not happen in my opinion. Is there any 
 possibility to change the lines so that they don't cross anymore?

 Cheers, Julia



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[Freesurfer] Displaying results from qdec on a single subject

2012-03-22 Thread Emily Rogalski
Hi All,

Is it possible to resample a .sig file from a group thickness analysis in
qdec so that the results could be displayed on a single subject's anatomy
rather than the fsaverage anatomy in tksurfer?

Thanks,

Emily

-- 
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Assistant Research Professor
Northwestern University
Cognitive Neurology and Alzheimer's Disease Center (CNADC)
320 E Superior Street
Searle Building 11th Floor
Chicago, IL 60611
312-503-1155 phone
312-908-8789 fax
erogal...@gmail.com
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Re: [Freesurfer] Displaying results from qdec on a single subject

2012-03-22 Thread Bruce Fischl
Hi Emily

yes, mri_surf2surf should do this for you.

cheers
Bruce
On Thu, 22 Mar 2012, Emily 
Rogalski wrote:

 Hi All,
 
 Is it possible to resample a .sig file from a group thickness analysis in 
 qdec so
 that the results could be displayed on a single subject's anatomy rather than 
 the
 fsaverage anatomy in tksurfer?
 
 Thanks,
 
 Emily
 
 --
 Emily J Rogalski, PhD
 Assistant Research Professor
 Northwestern University
 Cognitive Neurology and Alzheimer's Disease Center (CNADC)
 320 E Superior Street
 Searle Building 11th Floor
 Chicago, IL 60611
 312-503-1155 phone
 312-908-8789 fax
 erogal...@gmail.com
 

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[Freesurfer] Future of freesurfer

2012-03-22 Thread Nicolas Rannou
Hi all,

I'm  currently compiling/installing freesurfer on mac osx lion, ubuntu
12.04 (will be relased soon) and lots of packages which are required by
freesurfer appear to be outdated.
Is there any step-by-step installation/compilation tutorial somewhere in
the web?

Therefore I have a couple of questions:

Do you plan to update the default libraries to newer versions sometimes
soon?
(I'm not sure for how long building against old packages will build viable?)
Shouldn't freesurfer links against the current release of each library?

Regarding the build system, do you consider switching to cmake? It would
make easier to maintain, keep up to date and deploy freesurfer over mac and
linux?

Best,
Nicolas
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[Freesurfer] calculating DLPFC or frontal lobe grey and white matter volumes

2012-03-22 Thread sam bedford










Dear All



We want to find frontal
lobe grey and white matter volumes in a patient group to compare it
with control group. In particular, we want to see the grey and white matter 
volumes in the dorsolateral prefrontal cortex (DLPFC). However
we seem to be having problems finding this region on the processed
data for white matter volume (after recon-all command). It was previously 
suggested in this
mailing list that we can get grey matter volume for the DLPFC by
combining the following volumes:

 $hemi.G_frontal_middle.label
 $hemi.S_frontal_inferior.label
 $hemi.S_frontal_middle.label
We are wondering how to get white matter volumes in the same
region... 




If getting the DLPFC
volume is difficult then can we  just use the frontal grey and white
matter volumes to make between group comparisons. From aseg and aparc
files in the stats folder, adding all the following values below
would give us  frontal white and grey matter volumes. Or is there a
simpler and less time consuming way to calculate grey and white
matter volume in the frontal lobe?  








Frontal lobes - White Matter volume 




caudalmiddlefrontal
lateralorbitofrontal
medialorbitofrontal
paracentral
parsopercularis 

parsorbitalis 

parstriangularis
precentral
rostralmiddlefrontal
superiorfrontal
frontalpole 




Frontal lobes - Grey Matter volumes




G_and_S_frontomargin 

G_and_S_paracentral
 

G_and_S_subcentral 
 QQQ???
G_and_S_transv_frontopol
 

G_front_inf-Opercular 

G_front_inf-Orbital  

G_front_inf-Triangul   
   

G_front_middle  

G_front_sup
G_precentral  

S_front_inf

S_front_middle 
  

S_front_sup 

Thanks in advance
Sam 


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[Freesurfer] Spot Opened in Boston FreeSurfer course

2012-03-22 Thread Allison Stevens Player
Hi everyone,
We had a last minute drop-out from our Boston FreeSurfer course which 
takes place April 2nd through the 4th. If anyone is interested in taking 
this spot, please let me know.

Details about the course content, the registration fee, and other 
logistics can be found here:
http://surfer.nmr.mgh.harvard.edu/fswiki/CourseDescription

Allison
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[Freesurfer] Checkout release and stable branch

2012-03-22 Thread Nicolas Rannou
Hi all,

I followed the instructions on the wiki but it seems impossible to checkout
the stable and release branches?

[toor@linux:x86_64-Linux]...or/cvsroot/test$cvs -d
:pserver:anonym...@fsvm.nmr.mgh.harvard.edu:/usr/fscvsroot checkout -P -r
stable5 stable
cvs server: cannot find module `stable' - ignored
cvs [checkout aborted]: cannot expand modules


Did their name changed?

Is there a good way with cvs to list the available branches?
('cvs ls' not woking)

Thanks,
Nicolas
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Re: [Freesurfer] Checkout release and stable branch

2012-03-22 Thread Nick Schmansky
the last arg should be 'dev', not 'stable'.

 Hi all,

 I followed the instructions on the wiki but it seems impossible to
 checkout
 the stable and release branches?

 [toor@linux:x86_64-Linux]...or/cvsroot/test$cvs -d
 :pserver:anonym...@fsvm.nmr.mgh.harvard.edu:/usr/fscvsroot checkout -P -r
 stable5 stable
 cvs server: cannot find module `stable' - ignored
 cvs [checkout aborted]: cannot expand modules


 Did their name changed?

 Is there a good way with cvs to list the available branches?
 ('cvs ls' not woking)

 Thanks,
 Nicolas
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Re: [Freesurfer] Checkout release and stable branch

2012-03-22 Thread Nicolas Rannou
Thanks for the quick answer :)

I'm not very familiar with cvs and was assuming 'stable' was only the name
of the directory in which the code would be checked out!

Thanks!
Nicolas

On Thu, Mar 22, 2012 at 3:09 PM, Nick Schmansky
ni...@nmr.mgh.harvard.eduwrote:

 the last arg should be 'dev', not 'stable'.
  Hi all,
 
  I followed the instructions on the wiki but it seems impossible to
  checkout
  the stable and release branches?
 
  [toor@linux:x86_64-Linux]...or/cvsroot/test$cvs -d
  :pserver:anonym...@fsvm.nmr.mgh.harvard.edu:/usr/fscvsroot checkout -P
 -r
  stable5 stable
  cvs server: cannot find module `stable' - ignored
  cvs [checkout aborted]: cannot expand modules
 
 
  Did their name changed?
 
  Is there a good way with cvs to list the available branches?
  ('cvs ls' not woking)
 
  Thanks,
  Nicolas
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 is
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 e-mail
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[Freesurfer] make_average_subject failure

2012-03-22 Thread Klein, Holger
Dear Freesurfers,

Command line: make_average_subject --out average --subjects ... (n=60)

.
.
.
.
.
Applying LTAtransformInterp (resample_type 1)
writing to
/Volumes/Macintosh/freesurfer/Kontrollen//average/tmp/make_average_vol-tmp-15056/orig-A2/WE.mgh...
ERROR: failure writing
/Volumes/Macintosh/freesurfer/Kontrollen//average/tmp/make_average_vol-tmp-15056/orig-A2/WE.mgh
/Volumes/Macintosh/freesurfer/Kontrollen
ERROR: mri_convert failed.
ERROR: make_average_volume


Surface averaging was done without any problem, but the volume averaging


Any clue what's wrong?

Thanks in advance
Holger
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Re: [Freesurfer] ERROR: comparison in expression (FS with SGE)

2012-03-22 Thread Matt Glasser
I'm dredging this 2 year old post up for the benefit of Google and anyone
else who wonders about the cause of this.  It is a non-fatal error (for
FreeSurfer, but perhaps not other things) that is caused by having set the
variable:

POSIXLY_CORRECT=1

It causes bc (on Debian/Ubuntu) systems to fail when making comparisons
like:

echo '3.5  2.5' | bc -l

I am guessing (because this is what I was doing) that the poster was using
fsl_sub to launch FreeSurfer jobs in SGE.  fsl_sub sets this flag for some
reason, but commenting it out seems not to cause any problems.

Peace,

Matt.

-Original Message-
From: freesurfer-boun...@nmr.mgh.harvard.edu
[mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Xue, Feng
Sent: Sunday, March 14, 2010 1:37 PM
To: Bruce Fischl
Cc: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] ERROR: comparison in expression (FS with SGE)

Thanks! I would check them later.

On Mon, Mar 15, 2010 at 1:24 AM, Bruce Fischl
fis...@nmr.mgh.harvard.edu wrote:
 if it was a syntax error then recon-all wouldn't have finished, so I'm not
 sure what's going on. You should visually inspect the surfaces and
 segmentations to make sure they are all ok.

 cheers,
 Bruce

 On Mon, 15 Mar 2010, Xue, Feng wrote:

 Sorry, I didn't notice that the reply address was not the list, I've
 done re-post it.

 Is there any method to check whether it is ok? For SGE, it might only
 write errors to dot e files instead of warnings.

 It seemed like a shell syntax error, however, I don't have that
 experience to check the recon-all script.

 On Sun, Mar 14, 2010 at 11:24 PM, Bruce Fischl
 fis...@nmr.mgh.harvard.edu wrote:

 can you post this to the list? There are others better qualified to say
 what's going on. But if everything finished ok is there really a
problem?
 Maybe this is just a warning?
 On Sun, 14 Mar 2010, Xue, Feng wrote:

 Hi Bruce,

 Thanks for your reply. The recon-all.log said it finished without
 error. please find the whole scripts root in the attachment.
 I'm also running a raw testing with one subject and without
SGEMaybe
 I can report the result the day after tomorrow.

 BTW, I found in my 64bit Debian nodes, I repeated got the error as
below
 (standard_in) 2: Error: comparison in expression
 but in 32bit, I met both.

 for the GMail security restriction, I changed recon-all.cmd in the
 attachment to recon-all.cmds.

 On Sat, Mar 13, 2010 at 11:58 PM, Bruce Fischl
 fis...@nmr.mgh.harvard.edu wrote:

 what does the recon-all.log say? Did the recon finish correctly? Does
 this
 happen if you just run it on the command line?
 Bruce

 On Sat, 13 Mar 2010, Xue, Feng wrote:

 Dear Bruce  FS experts,

 Please forgive my re-post, for I havn't got any response from last
 post.
 I do appreciate if anyone could give me a hint or suggestion.

 ++

 We are running freesurfer with Sun GridEngine. Currently, we
 repeatedly got this error in SGE's job error log file on some data
 when doing recon_all:

 $ cat recon_xf.e437
 (standard_in) 2: Error: comparison in expression
 $ cat recon_xf.e431
 (standard_in) 2: comparison in expression

 I also checked the recon-all-status.log file, but not error was
found.

 Has anyone met this problem? Is it critical?
 Thanks in advance.

 --
 Best Regards

 Xue, Feng Phd. candidate
 Major in Developmental Cognitive Neuroscience

 National Key Laboratory of Cognitive Neuroscience and Learning
 Beijing Normal University
 Beijing, China. 100875
 Tel: +86-13810154455
 web: http://psychbrain.bnu.edu.cn
 ==
 Welcome to MuDuo JinSheng BBS @ Beijing Normal University
 telnet://bbs.mdjs.org
 http://bbs.mdjs.org
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-- 
Best Regards

Xue, Feng Phd. candidate
Major in Developmental Cognitive Neuroscience

National Key Laboratory of Cognitive Neuroscience and Learning
Beijing Normal University
Beijing, China. 100875
Tel: +86-13810154455
web: http://psychbrain.bnu.edu.cn
==
Welcome to MuDuo JinSheng BBS @ Beijing Normal University
telnet://bbs.mdjs.org
http://bbs.mdjs.org

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Re: [Freesurfer] make_average_subject failure

2012-03-22 Thread Bruce Fischl

did you run out of disk space? Does that path exist?

On Thu, 22 Mar 2012, Klein, Holger wrote:


Dear Freesurfers, 
Command line: make_average_subject --out average --subjects ... (n=60) 

.
.
.
.
.
Applying LTAtransformInterp (resample_type 1)
writing 
to/Volumes/Macintosh/freesurfer/Kontrollen//average/tmp/make_average_vol-tmp-15056/o
rig-A2/WE.mgh...
ERROR: failure 
writing/Volumes/Macintosh/freesurfer/Kontrollen//average/tmp/make_average_vol-tmp-15056/o
rig-A2/WE.mgh
/Volumes/Macintosh/freesurfer/Kontrollen
ERROR: mri_convert failed.
ERROR: make_average_volume


Surface averaging was done without any problem, but the volume averaging 

Any clue what's wrong?

Thanks in advance
Holger

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[Freesurfer] QDEC with cluster-wise p=.1

2012-03-22 Thread Jeff Sadino
Hello FreeSurfers,

I want to do several cluster-wise corrections at a p value of .1,
preferably in QDEC.  To create the new template cluster, I am using this
command:
mri_mcsim --o test --base mc-z --surf fsaverage lh --nreps 1 --fwhm 10
Is there a way that I can tell mri_mcsim to do a threshold of 1.00 (p=.1)
and only the abs sign?

Thank you,
Jeff Sadino
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[Freesurfer] Jacobian Questions

2012-03-22 Thread Jeff Sadino
Hello,

Since the jacobian files contain only positive numbers, is there any way to
make a distinction between a brain area that needs to be stretched bigger
to fit the template versus a brain area that needs to be squished smaller?

fsaverage is comprised of 40 subjects, but I wonder if the jacobian is most
accurate only for my subjects that have the same age as the fsaverage mean?
 If so, then the younger subjects would need to be squished and the older
subjects would need to be stretched.  But since the jacobian is always
positive, then on a scatterplot of jacobian versus age, this would look
like a hump centered on the fsaverage mean age.  Am I on the right track
with this?

Thank you,
Jeff
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[Freesurfer] Cortical Normalization Questions

2012-03-22 Thread Jeff Sadino
Hello,

For cortical thickness normalizations, Bruce said not to normalize based on
a HBM abstract (
http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg06646.html).
 Is this still the consensus?

For cortical volume, it is pretty standard to normalize to eTIV.

For cortical surface area (jacobian), I couldn't find any information on
the wiki.  Does anyone have any recommendations?

Thank you,
Jeff
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Re: [Freesurfer] Jacobian Questions

2012-03-22 Thread Bruce Fischl

Hi Jeff

1 means compressed and 1 means expanded. You can take the log if you want 
to turn it into the real line. I'm not sure age matters that much for the 
white matter surface, although it would for the pial one


cheers
Bruce

On Thu, 22 Mar 2012, Jeff Sadino 
wrote:



Hello,
Since the jacobian files contain only positive numbers, is there any way to 
make a
distinction between a brain area that needs to be stretched bigger to fit the
template versus a brain area that needs to be squished smaller?

fsaverage is comprised of 40 subjects, but I wonder if the jacobian is most
accurate only for my subjects that have the same age as the fsaverage mean?  If 
so,
then the younger subjects would need to be squished and the older subjects would
need to be stretched.  But since the jacobian is always positive, then on a
scatterplot of jacobian versus age, this would look like a hump centered on the
fsaverage mean age.  Am I on the right track with this?

Thank you,
Jeff

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Re: [Freesurfer] Cortical Normalization Questions

2012-03-22 Thread Bruce Fischl

Hi Jeff

yes, I think this is still our recommendation for thickness, although 
perhaps David Salat can verify. As far as surface area, you might get 
Anderson Winkler to send you a preprint of his newly accepted paper on 
surface area comparisons and how to do them properly. I would have said 
normalize by the 2/3 root of ICV (maybe David can comment on this as well)


cheers
Bruce


On Thu, 22 Mar 2012, Jeff Sadino wrote:


Hello,
For cortical thickness normalizations, Bruce said not to normalize based on a 
HBM
abstract
(http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg06646.html).  Is
this still the consensus?

For cortical volume, it is pretty standard to normalize to eTIV.

For cortical surface area (jacobian), I couldn't find any information on the 
wiki.
 Does anyone have any recommendations?

Thank you,
Jeff

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Re: [Freesurfer] Cortical Normalization Questions

2012-03-22 Thread Michael Harms

Hi Jeff,
I personally like the idea of using average thickness as a covariate to
control for a reduction in whole brain thickness, and have used that
approach in a paper.  If the Abstract that you mentioned indicated that
this is flawed, I'd be curious to know what the reason was...

cheers,
-MH

On Thu, 2012-03-22 at 21:00 -0400, Bruce Fischl wrote:
 Hi Jeff
 
 yes, I think this is still our recommendation for thickness, although 
 perhaps David Salat can verify. As far as surface area, you might get 
 Anderson Winkler to send you a preprint of his newly accepted paper on 
 surface area comparisons and how to do them properly. I would have said 
 normalize by the 2/3 root of ICV (maybe David can comment on this as well)
 
 cheers
 Bruce
 
 
 On Thu, 22 Mar 2012, Jeff Sadino wrote:
 
  Hello,
  For cortical thickness normalizations, Bruce said not to normalize based on 
  a HBM
  abstract
  (http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg06646.html). 
   Is
  this still the consensus?
  
  For cortical volume, it is pretty standard to normalize to eTIV.
  
  For cortical surface area (jacobian), I couldn't find any information on 
  the wiki.
   Does anyone have any recommendations?
  
  Thank you,
  Jeff
  
 
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Re: [Freesurfer] Cortical Normalization Questions

2012-03-22 Thread Bruce Fischl
Yes, I think Mike's approach is a good one also, although you have to be clear 
about the somewhat different hypothesis you are testing



On Mar 22, 2012, at 9:15 PM, Michael Harms mha...@conte.wustl.edu wrote:

 
 Hi Jeff,
 I personally like the idea of using average thickness as a covariate to
 control for a reduction in whole brain thickness, and have used that
 approach in a paper.  If the Abstract that you mentioned indicated that
 this is flawed, I'd be curious to know what the reason was...
 
 cheers,
 -MH
 
 On Thu, 2012-03-22 at 21:00 -0400, Bruce Fischl wrote:
 Hi Jeff
 
 yes, I think this is still our recommendation for thickness, although 
 perhaps David Salat can verify. As far as surface area, you might get 
 Anderson Winkler to send you a preprint of his newly accepted paper on 
 surface area comparisons and how to do them properly. I would have said 
 normalize by the 2/3 root of ICV (maybe David can comment on this as well)
 
 cheers
 Bruce
 
 
 On Thu, 22 Mar 2012, Jeff Sadino wrote:
 
 Hello,
 For cortical thickness normalizations, Bruce said not to normalize based on 
 a HBM
 abstract
 (http://www.mail-archive.com/freesurfer@nmr.mgh.harvard.edu/msg06646.html). 
  Is
 this still the consensus?
 
 For cortical volume, it is pretty standard to normalize to eTIV.
 
 For cortical surface area (jacobian), I couldn't find any information on 
 the wiki.
 Does anyone have any recommendations?
 
 Thank you,
 Jeff
 
 
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