[Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Jutta Ernst
Dear Freesurfer's

I draw a roi to extract the cortical thickness for my two groups and that
worked fine.
Now I'm trying to export the very same roi to use it for further
connectivity analysis.
Can anyone please help me and tell me how to do it?
Thanks in advance!! :-)

Cheers
Jutta
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Re: [Freesurfer] ADNI freesurfer annotation/labels file

2014-05-08 Thread Bruce Fischl
Hi Tanya

what kind of labels do you mean? If it is the cortical parcels they are 
in the label subdir in the *.annot files.

cheers
Bruce
On Wed, 7 May 2014, Tanya wrote:

 Hi Freesurfers,I'd like to work with ADNI freesurfer data to do analysis on
 cortical segments, but could not find the annotation files for these
 studies. Where in the ADNI freesurfer files can I find the annotation/labels
 files containing the labels for each vertex on the cortical surfaces?
 
 Thanks!
 

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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Bruce Fischl
Hi Jutta

we need more details - what format are you trying to conver the ROI to? 
What software are you planning to use to do the connectivity analysis?

cheers
Bruce


On Thu, 8 May 2014, Jutta Ernst wrote:

 
 
 Dear Freesurfer's
 
 I draw a roi to extract the cortical thickness for my two groups and that
 worked fine.
 Now I'm trying to export the very same roi to use it for further
 connectivity analysis.
 Can anyone please help me and tell me how to do it?
 Thanks in advance!! :-)
 
 Cheers
 Jutta
 
 

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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Jutta Ernst

Hi

Nifti would be great and the software would be Data Processing Assistant 
for Resting-State fMRI (/DPARSF/).


Cheers, Jutta


On 05/08/2014 02:38 PM, Bruce Fischl wrote:

Hi Jutta

we need more details - what format are you trying to conver the ROI to?
What software are you planning to use to do the connectivity analysis?

cheers
Bruce


On Thu, 8 May 2014, Jutta Ernst wrote:



Dear Freesurfer's

I draw a roi to extract the cortical thickness for my two groups and that
worked fine.
Now I'm trying to export the very same roi to use it for further
connectivity analysis.
Can anyone please help me and tell me how to do it?
Thanks in advance!! :-)

Cheers
Jutta




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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Bruce Fischl
and what format is your ROI in?
On Thu, 8 May 2014, Jutta Ernst wrote:

 Hi
 
 Nifti would be great and the software would be Data Processing Assistant for
 Resting-State fMRI (DPARSF).
 
 Cheers, Jutta
 
 
 On 05/08/2014 02:38 PM, Bruce Fischl wrote:
 
 Hi Jutta
 
 we need more details - what format are you trying to conver the ROI to? 
 What software are you planning to use to do the connectivity analysis?
 
 cheers
 Bruce
 
 
 On Thu, 8 May 2014, Jutta Ernst wrote:
 
 
 Dear Freesurfer's
 
 I draw a roi to extract the cortical thickness for my two groups and that
 worked fine.
 Now I'm trying to export the very same roi to use it for further
 connectivity analysis.
 Can anyone please help me and tell me how to do it?
 Thanks in advance!! :-)
 
 Cheers
 Jutta
 
 
 
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 contains patient information, please contact the Partners Compliance HelpLin
 e at
 http://www.partners.org/complianceline . If the e-mail was sent to you in er
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 erly
 dispose of the e-mail.
 
 
 

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Re: [Freesurfer] Longitudinal design

2014-05-08 Thread Tudor Popescu
Sorry for the repeat, wasn't sure whether this was received the first time.
Tudor


On 6 May 2014 19:55, Tudor Popescu tud...@gmail.com wrote:

 Dear FS list,

 I have structural data from a learning study (prepost-training scans,
 with 3 groups). Although the training was only one week, I'm guessing from
 an analysis point of view, this still qualifies as longitudinal. I want to
 check for

- the main within-subjects effect of time point (prepost)
- the main between-subjects effect of group (treatment A, treatment B,
control),
- the time x group interaction

 I intend to look at thickness, surface area, volume, and lGI.

 I read on the 
 wikihttp://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalProcessingthat FS 
 is currently not optimal for longitudinal analyses. I intend my
 FreeSurfer analysis to supplement a VBM analysis done in FSL. In case it is
 in fact a good idea to do this, my questions (not covered in the
 'longitudinal' wiki page) are:

 1) Can QDEC be used for such an analysis, and if so, what would be
 different as compared to a cross-sectional (no temporal/within factor)
 study?

 2) Also, is the pre-processing stage any different?

 3) In FSL, for longitudinal designs you do stats on images obtained as the
 difference between consecutive time points. Does this have to be done in
 FreeSurfer as well, and if so, is it done at the recon-all level or only at
 the stats (QDEC) level?

 Thanks!

 Tudor



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Re: [Freesurfer] Longitudinal design

2014-05-08 Thread Bruce Fischl
Hi Tudor

I'll leave ths stats question to Martin or Jorge, but I'm not sure why the 
wiki would say out longitudinal stream is not optimal. It is certainly as 
optimal as we have had the resources to make it, although there are a long 
list of things we would still like to do.

cheers
Bruce

On Thu, 8 May 2014, 
Tudor Popescu wrote:

 Sorry for the repeat, wasn't sure whether this was received the first time.
 Tudor
 
 
 On 6 May 2014 19:55, Tudor Popescu tud...@gmail.com wrote:
   Dear FS list,
 
 I have structural data from a learning study (prepost-training scans,
 with 3 groups). Although the training was only one week, I'm guessing
 from an analysis point of view, this still qualifies as longitudinal.
 I want to check for
  *  the main within-subjects effect of time point (prepost)
  *  the main between-subjects effect of group (treatment A, treatment
 B, control),
  *  the time x group interaction
 I intend to look at thickness, surface area, volume, and lGI.
 
 I read on the wiki that FS is currently not optimal for longitudinal
 analyses. I intend my FreeSurfer analysis to supplement a VBM analysis
 done in FSL. In case it is in fact a good idea to do this, my
 questions (not covered in the 'longitudinal' wiki page) are:
 
 1) Can QDEC be used for such an analysis, and if so, what would be
 different as compared to a cross-sectional (no temporal/within factor)
 study?
 
 2) Also, is the pre-processing stage any different?
 
 3) In FSL, for longitudinal designs you do stats on images obtained as
 the difference between consecutive time points. Does this have to be
 done in FreeSurfer as well, and if so, is it done at the recon-all
 level or only at the stats (QDEC) level?
 
 Thanks!
 
 Tudor
 
 
 
 

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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Bruce Fischl
then you probably want to use mri_label2vol to sample it into the volume. 
If the output name has the extension .nii it will be in nifti format

cheers
Bruce



On Thu, 8 May 2014, Jutta Ernst wrote:

 It's a label file...


 On 05/08/2014 02:56 PM, Bruce Fischl wrote:
 and what format is your ROI in?
 On Thu, 8 May 2014, Jutta Ernst wrote:

 Hi

 Nifti would be great and the software would be Data Processing Assistant for
 Resting-State fMRI (DPARSF).

 Cheers, Jutta


 On 05/08/2014 02:38 PM, Bruce Fischl wrote:

 Hi Jutta

 we need more details - what format are you trying to conver the ROI to?
 What software are you planning to use to do the connectivity analysis?

 cheers
 Bruce


 On Thu, 8 May 2014, Jutta Ernst wrote:


 Dear Freesurfer's

 I draw a roi to extract the cortical thickness for my two groups and that
 worked fine.
 Now I'm trying to export the very same roi to use it for further
 connectivity analysis.
 Can anyone please help me and tell me how to do it?
 Thanks in advance!! :-)

 Cheers
 Jutta



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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Jutta Ernst
It's a label file...


On 05/08/2014 02:56 PM, Bruce Fischl wrote:
 and what format is your ROI in?
 On Thu, 8 May 2014, Jutta Ernst wrote:

 Hi

 Nifti would be great and the software would be Data Processing Assistant for
 Resting-State fMRI (DPARSF).

 Cheers, Jutta


 On 05/08/2014 02:38 PM, Bruce Fischl wrote:

 Hi Jutta

 we need more details - what format are you trying to conver the ROI to?
 What software are you planning to use to do the connectivity analysis?

 cheers
 Bruce


 On Thu, 8 May 2014, Jutta Ernst wrote:


 Dear Freesurfer's

 I draw a roi to extract the cortical thickness for my two groups and that
 worked fine.
 Now I'm trying to export the very same roi to use it for further
 connectivity analysis.
 Can anyone please help me and tell me how to do it?
 Thanks in advance!! :-)

 Cheers
 Jutta



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 addressed. If you believe this e-mail was sent to you in error and the e-mai
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 contains patient information, please contact the Partners Compliance HelpLin
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 http://www.partners.org/complianceline . If the e-mail was sent to you in er
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 erly
 dispose of the e-mail.




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[Freesurfer] 2x3 ANOVA question

2014-05-08 Thread sabin khadka
Hi all,
I am trying to run 2x3 factorial model correcting for age, sex and intracranial 
volume. Just to give you insight in my data I have my fsgd file as 

GroupDescriptorFile 1
Title DOSS analysis 2x3 factorial
Class MaleGroup1Low

Class MaleGroup1Medium
Class MaleGroup1High
Class MaleGroup2Low
Class MaleGroup2Medium
Class MaleGroup2HighClass FemaleGroup1Low

Class FemaleGroup1Medium
Class FemaleGroup1High
Class FemaleGroup2Low
Class FemaleGroup2Medium
Class FemaleGroup2High
Variables Age normVol
Input SUB001 MaleGroup1Low 18 0.4

And also my contrast files as 

Group1Group2.mtx
[1 1 1 -1 -1 -1 1 1 1 -1 -1 -1]/3

MainEffectState.mtx
0.5 -0.5 0 0.5 -0.5 0 0.5 -0.5 0 0.5 -0.5 0
0 0.5 -0.5 0 0.5 -0.5 0 0.5 -0.5 0 0.5 -0.5

HighvLow.mtx
-0.5 0 0.5 -0.5 0 0.5 -0.5 0 0.5 -0.5 0 0.5
HighvMed.mtx
0 -0.5 0.5 0 -0.5 0.5 0 -0.5 0.5 0 -0.5 0.5

GroupxState-interaction.mtx
0.5 -0.5 0 -0.5 0 0.5 0.5 -0.5 0 -0.5 0 0.5
0.5 0 -0.5 -0.5 0 0.5 0.5 0 -0.5 -0.5 0 0.5

I'd appreciate if anyone could please let me know that my design is correct.

Thanks for help.

-Sabin
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Re: [Freesurfer] Fwd: extracting rois for connectivity analysis

2014-05-08 Thread Jutta Ernst
Thank you, that solved it :-)cheers

 Am 08.05.2014 um 15:56 schrieb Bruce Fischl fis...@nmr.mgh.harvard.edu:
 
 then you probably want to use mri_label2vol to sample it into the volume. 
 If the output name has the extension .nii it will be in nifti format
 
 cheers
 Bruce
 
 
 
 On Thu, 8 May 2014, Jutta Ernst wrote:
 
 It's a label file...
 
 
 On 05/08/2014 02:56 PM, Bruce Fischl wrote:
 and what format is your ROI in?
 On Thu, 8 May 2014, Jutta Ernst wrote:
 
 Hi
 
 Nifti would be great and the software would be Data Processing Assistant 
 for
 Resting-State fMRI (DPARSF).
 
 Cheers, Jutta
 
 
 On 05/08/2014 02:38 PM, Bruce Fischl wrote:
 
 Hi Jutta
 
 we need more details - what format are you trying to conver the ROI to?
 What software are you planning to use to do the connectivity analysis?
 
 cheers
 Bruce
 
 
 On Thu, 8 May 2014, Jutta Ernst wrote:
 
 
 Dear Freesurfer's
 
 I draw a roi to extract the cortical thickness for my two groups and that
 worked fine.
 Now I'm trying to export the very same roi to use it for further
 connectivity analysis.
 Can anyone please help me and tell me how to do it?
 Thanks in advance!! :-)
 
 Cheers
 Jutta
 
 
 
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 is
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 e-mai
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 HelpLin
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 er
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 prop
 erly
 dispose of the e-mail.
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Re: [Freesurfer] problem with pial surface reconstruction using T1 (MPRAGE) and T2 (SPACE) weighted images

2014-05-08 Thread Bruce Fischl

Hi Emil

how do the surfaces look before you apply the T2 deformation? And how do 
they look visualized over the T2 instead of the T1?


cheers
Bruce

On Thu, 8 May 2014, Emil H.J. Nijhuis 
wrote:



Hi,

I have been using Freesurfer v5.3 to perform surface reconstruct for 1mm
isotropic T1 (MPRAGE) and T2 (SPACE) weighted images from a Siemens 3T Trio
scanner with a 32-channel head coil. Unfortunately for half of my subjects I
receive an rather odd pial surface artefact, while the 'white' surfaces do
not suffer from the same issue.

The command line I have used was:

recon-all -all -subjid subjectid -T2  subjectdir/mri/orig/T2.mgz -T2pial
-3T

Are you familiar with this issue and do you have some advice for me?

Thank you very much for your help.

Yours sincerely,

 Emil

--
--
Emil H.J. Nijhuis, PhD
Researcher - Division of Diagnostic and Interventional Neuroradiology
University Hospital Basel
Petersgraben 4
CH 4031 Basel Switzerland



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[Freesurfer] Information on automatic segmentation method

2014-05-08 Thread dorothee schoemaker
Hi,

From what I understand, Freesurfer's automatic segmentation pipeline is
partly based on a training set of subjects manually segmented. Is there a
way to get more information on which protocol/guideline was used to
manually segment (or define anatomical boundaries) these subjects at the
baseline? I am unable to find this information...

Thank you in advance for your assistance!
Dorothée.
-- 
*PhD candidate in Clinical Psychology*
*McGill University*
*McGill Centre for Studies in Aging*
*Montreal, CANADA*
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[Freesurfer] Information on automatic segmentation method

2014-05-08 Thread Dorothee Schoemaker
Hi,

From what I understand, Freesurfer's automatic segmentation pipeline is partly 
based on a training set of subjects manually segmented. Is there a way to get 
more information on which protocol/guideline was used to manually segment (or 
define anatomical boundaries) these subjects at the baseline? I am unable to 
find this information...

Thank you in advance for your assistance!
Dorothée.
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Re: [Freesurfer] Information on automatic segmentation method

2014-05-08 Thread Bruce Fischl

Hi Dorothy

yes, this is referred to in our 2002 Neuron paper - we use the CMA 
segmentation procedure/definitions  (see the references in that paper)


cheers
Bruce


On Thu, 8 May 2014, dorothee schoemaker wrote:


Hi,
From what I understand, Freesurfer's automatic segmentation pipeline is
partly based on a training set of subjects manually segmented. Is there a
way to get more information on which protocol/guideline was used to manually
segment (or define anatomical boundaries) these subjects at the baseline? I
am unable to find this information...

Thank you in advance for your assistance!
Dorothée.
--
PhD candidate in Clinical PsychologyMcGill University
McGill Centre for Studies in Aging
Montreal, CANADA

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[Freesurfer] nonlinear models in longitudinal analysis

2014-05-08 Thread Jodie Davies-Thompson
Dear Freesurfer experts,

I am attempting to do a longitudinal analysis of cortical thickness with 3 
timepoints. So far, I have successfully completed the analysis for 
long_mris_slopes comparing timepoint 1 to timepoint 2, timepoint 2 to timepoint 
3, and a linear increase for timepoint 1 to 2 to 3.

However, I am primarily interested in finding regions which show a) an increase 
between timepoint 1 and 2, but no difference between 2 and 3, and b) no 
difference between timepoint 1 and 2, but an increase between 2 and 3. 

Would the correct way of 'modelling' these two in the qdec file be:

a)
fsid fsid-base years
day1 base 0
day2 base 3
day3 base 3

and b)
fsid fsid-base years
day1 base 0
day2 base 0
day3 base 3

All the best,
Jodie

-
---
Jodie Davies-Thompson, Postdoctoral Fellow
Department of Ophthalmology  Visual Sciences
UBC/VGH Eye Care Centre
2550 Willow Street
Vancouver, BC, V5Z 3N9
Canada
Tel: 604-875-4111 ext 69003


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[Freesurfer] flash v.s. mprage

2014-05-08 Thread Gregory Kirk
looking at the docs available it seems that in general
flash is prefered but it seems that for cortical thickness studies you
may still favor the mprage ? all with good parameter setting of course.

thanks in advance for any clarifying comments you may have

Greg
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