Sorry for the repeat, wasn't sure whether this was received the first time. Tudor
On 6 May 2014 19:55, Tudor Popescu <tud...@gmail.com> wrote: > Dear FS list, > > I have structural data from a learning study (pre&post-training scans, > with 3 groups). Although the training was only one week, I'm guessing from > an analysis point of view, this still qualifies as longitudinal. I want to > check for > > - the main within-subjects effect of time point (pre&post) > - the main between-subjects effect of group (treatment A, treatment B, > control), > - the time x group interaction > > I intend to look at thickness, surface area, volume, and lGI. > > I read on the > wiki<http://surfer.nmr.mgh.harvard.edu/fswiki/LongitudinalProcessing>that FS > is currently not optimal for longitudinal analyses. I intend my > FreeSurfer analysis to supplement a VBM analysis done in FSL. In case it is > in fact a good idea to do this, my questions (not covered in the > 'longitudinal' wiki page) are: > > 1) Can QDEC be used for such an analysis, and if so, what would be > different as compared to a cross-sectional (no temporal/within factor) > study? > > 2) Also, is the pre-processing stage any different? > > 3) In FSL, for longitudinal designs you do stats on images obtained as the > difference between consecutive time points. Does this have to be done in > FreeSurfer as well, and if so, is it done at the recon-all level or only at > the stats (QDEC) level? > > Thanks! > > Tudor > > >
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