Re: Jaundice and meconium; Minimum service levels

2002-03-13 Thread Kleimar

Yes I agree Leigh, it is the jaundice in the first 24 hrs that is concerning 
with this baby and hopefully the concern with meconium passage was not a red 
herring. It does seems that the obvious potential causes of hemolysis in the 
baby (and hence, jaundice): Rh factor and ABO incompatibility were ruled out 
by the mother's blood group and type: B+. There could be several other 
syndromes involved all of which are quite rare (Gilbert's syndrome comes to 
mind, never seen it just read about it, in relation to early jaundice). 
However, it seems that starting simple and as gentle as possible can be a 
good thing (removing the mec), while keeping a careful eye on the baby. Was 
there  any reason for the baby to have experience bruising or hemmorhage? 
Kirsten, was this the end of the story? Was the delayed passage of mec in the 
first day responsibel for the jaundice? And while I know any jaundice in the 
first 24 hrs is a concern, how extensive was it? The only baby I personally 
have seen who had some jaundice on the first day which increased over the 
next week was with a mom who developed fulminating HELLP syndrome in labor 
(we had transfered to the hospital for failure to progress at 3-4 cm but no 
concerning BP's). On arrival at the hospital her BP was more elevated than it 
had been but still less than 140/90. When it didn't dip after she had an 
epidural the OB ordered PIH labs (actually apologizing for being conservative 
and CYA). She was as surprised as all of us when they can back elevated. Here 
we use mag sulfate for preventing seizures, so our poor mom had to put up 
with the side effects during pushing (she went to complete in 2 hours after 
getting the epidural). She birthed her lovely 8 lb baby in about 45 minutes. 
There was heavy mec at birth and baby did need some resusc. but was really 
quite fine (Apgars 7/9). The hospital staff were fastidious about checking 
the baby for jaundice and when he did yellow up on the first day checked his 
bilirubin levels, they were not at a level requiring therapy but they were 
high and went higher. The parents actually refused phototherapy, and the baby 
did recover after losing weight down to 7lb in the first week, and causing us 
all some concern (they discharged on day 2, we visited on day 3 and called in 
the pediatrician to assess the baby, bili levels were high and borderline 
(sorry I can't remember the numbers or the units)) but the parents were 
convinced all would be ok, and it was, once the milk really came in, but he 
was always pooping (right from birth) and peeing and nursing around the 
clock. Long story. 

I  searched the net for associations of newborn jaundice and HELLP syndrome, 
and all I found was an association, but no explanation. I am assuming that 
one of the enzymes that causes hemolysis in the mum can cross the placenta 
and cause hemolysis in the baby, but I am making that up. Does anyone know or 
does no one know? Associating jaundice with the baby of a mom with 
fulmimating HELLP  seemed to be tacit knowledge on the postnatal ward at the 
hospital, but maybe they check bili levels on all their babies (I am sure 
they check on all those jaundiced in the first 24 hrs). This mom too had no 
blood incaompatibility problem she is A+.

marilyn
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Re: Jaundice and meconium

2002-03-10 Thread Kleimar

Dear Kirsten: I am with you in that the jaundice by 24hrs seems a little 
early to be blaming it on unpassed mec. I have seen p(a)eds here (USA, 
Seattle and one in California) give suppositories to babies who are a little 
lethargic and  yellow on  days 4 or 5, however the first 24 hrs is a 
different story. But it couldn't be ABO or Rh incompatibility: you ruled that 
out.  marilyn
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Re: Jaundice and meconium

2002-03-10 Thread Mary Murphy

Maybe the problem is in the phrase looking jaundiced. Its not a very
scientific basis on which to diagnose a pathological problem.  Don't know
about the meconium 's effect at such an early time. I await further input.
Cheers, MM


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Re: Jaundice and meconium

2002-03-10 Thread Andrea Quanchi

Kirsten, Quickly and off the top of my head

Bilirubin is reabsorbed from the bowel raising bilirubin levels in the 
foetus but is cleared from the system by the placenta and the developing 
foetal liver etc. After birth the placenta is lost to the neonate making 
it solely responsible for its own clearance of bilirubin.  The sooner 
mec is passed then this source of reabsorption is lost and this is one 
very important reason why early breastfeeding is so important. Can 
bilirubin levels rise enough from this source alone to make the baby 
jaundice in the first 24 hours? Possible but less likely than other 
reasons such as ABO which is more usual in the first 24 hours.  Good 
source of info Blackburn  Loper (1992) Maternal. Fetal  neonata 
Physiology: A clinical perspective,  Saunders

Andrea Quanchi

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RE: Jaundice and meconium

2002-03-10 Thread Johnston

Dear Kirsten
I am going to give my nod to the OB nurses in this case.  If I saw a baby 
at 24 hours, who has not yet passed decent amounts of meconium, I would be 
asking why.  Particularly if jaundice is present.  There may be other 
causes, such as Abo or another blood incompatibility factor, but mec can 
contribute.  I would not use a thermometer or suppository, but I would 
massage around the baby's anus with my finger and some gentle oil.  By 
holding bub's legs up against his abdo, you can assist the baby's efforts 
to push it out.  If this doesn't work you have to wonder if there could be 
an obstruction, and watch for meconium ileus. (Animal mothers are often 
observed to lick their baby's bottoms, and encourage bowel actions that 
way.)

Early suckling gives the baby colostrum which has a laxative effect. 
 Babies who don't get the colostrum early in their lives may become 
jaundiced for no other reason than delayed meconium passage.

Best wishes from another aussie who spent a considerable time in USA with a 
green card, and experienced maternity services as a consumer.

Joy Johnston


-Original Message-
From:   Kirsten Blacker [SMTP:[EMAIL PROTECTED]]
Sent:   Monday, March 11, 2002 4:11 AM
To: [EMAIL PROTECTED]
Subject:Jaundice and meconium

HI all,

A question for the more phyisiologically minded amongst us. I was caring 
for
a mother-baby the other day. At about 24 hours of age the baby already was
looking jaundiced, and had not pooped. The OB nurses I work with seem to
think that BECAUSE the baby had not yet passed mec, that was why he was
looking jaundiced, which just didn't sit right with me, particularly at 24
hours of age. So they stimulated the rectum with a thermometer, and got a
nice cot full of the best black stuff, which made them happy. They told mum
t hen that everything should be fine because the baby had pooped now. I
reinforced to mum frequent breastfeeding, and also quickly reviewed blood
group for ABO incompatability (mum was B+).
ANYWAY, my question is, particularly at such an early age was the 
connection
reasonable? The theory seemed to be that the bilirubin was being reabsorbed
from the gut and causing jaundice, which doesn't sound 'right' to me.
Thoughts, oh wise ones?

Kirsten Blacker
infliciting her crazy Australian ways on the unsuspecting American public 
in
Minnesota, USA.
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