[R-sig-phylo] Substitution model for codon alignment

2017-02-23 Thread Bhuller, Ravneet
Hi All,

I want to build a phylogenetic tree using codon alignment which is huge (280 
MB). But there is no online information about suitable substitution models for 
codon alignment: is it HKY or GTR or any other? All the information available 
is about the substitution models for protein or nucleotide sequences. If anyone 
has created a phylogenetic tree based on codon alignment, your help will be 
much appreciated.

Many thanks for your attention.

Kind regards,

Ravneet
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[R-sig-phylo] Negative transition rates in diversitree

2017-02-23 Thread Miguel.Verdu
Hi all

I am fitting multitrait MuSSE models in the diversitree package to study 
correlated evolution between binary variables and some transition rates (qij) 
are negative. What is the meaning of negative transition rates? 

Thanks in advance


Miguel Verdú

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[R-sig-phylo] simulate additive trees based on ultrametric trees

2017-02-23 Thread Juan Antonio Balbuena

  
  
Hi all
I am using core-gen (Keller-Schmidt et al. 2011
  https://www.bioinf.uni-leipzig.de/Publications/PREPRINTS/11-013.pdf)
  to simulate host and parasite phylogenies. For each instance, a
  get a pair of ultrametric trees reflecting the coevolutionary
  history of host and parasite taxa. 

I was wondering what is the best way to simulate gene trees (i.e.
  additive trees) preserving the topology of the ultrametric ones. I
  tried to simulate sequence evolution (1000 nucleotids) under the
  GTR +Γ evolution model, using phylosim, and reconstruct the
  phylogenies by ML and BI. The problem is that the resulting
  phylogenies differ from the original topologies. 

Any help will be much appreciated. Thank you very much for your
  attention.

Juan A. Balbuena

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Juan
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Biology 
University of
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