_Ghosted Journal Articles Undermine Integrity of  Medicine_ 
(http://www.theoneclickgroup.co.uk/news.php?start=2800&end=2820&view=yes&id=3667#newspost)
 
_http://www.theoneclickgroup.co.uk/news.php?start=2800&end=2820&view=yes&id=
3667#newspost_ 
(http://www.theoneclickgroup.co.uk/news.php?start=2800&end=2820&view=yes&id=3667#newspost)
 
 
ALLIANCE FOR  HUMAN RESEARCH PROTECTION (AHRP)
A Catalyst for Public Debate:  Promoting Openness, Full Disclosure, and 
Accountability 
 
 
For years we have disseminated reports documenting one after  another 
uncovered case of corruption demonstrating that so-called **peer  review** is a 
sham: clinical trials, journal publications, and the practice of  medicine 
have been corrupted by the commercial influence of pharmaceutical  companies. 
 
 
Today's New York Times reports (below) that **court documents  provide a 
paper trail showing that Wyeth contracted with a medical  communications 
company to outline articles, draft them and then solicit top  physicians to 
sign 
their names, even though many of the doctors contributed  little or no 
writing.** 
 
 
It is a sordid example of corruption in medicine, but hardly  unique. In 
this case, 26 ghostwritten articles signed by prominent  academic Obg/ Gyn 
physicians, were published in 18  journals, promoting Wyeth's hormone 
replacement therapy,  Premarin--a treatment that has been linked to increased 
breast  
cancer, stoke, and dementia. 
 
 
The issue of ghostwritten promotional articles, signed by  prominent 
academic scientists at prestigious medical centers, is not a newly  discovered 
form of corruption. It was raised as early as 1998 (Carey, Fontarosa,  et al) 
[1]. 
 
 
Last year, an article in  the Journal of the American Medical Association 
(JAMA) revealed  that Merck commissioned ghostwriters to produce dozens of 
articles pushing  Vioxx, a drug that caused thousands of cardiac deaths. And 
this  year, documents uncovered in an Australian court showed that Merck even 
 commissioned a fake journal published by Elsevier: **The drug  company 
also allegedly produced an entire journal - called The Australasian  Journal of 
Bone and Joint Medicine - and passed it off as an independent peer  review 
publication.** See _HERE_ (http://www.the-scientist.com/blog/print/55671/)  

_http://www.the-scientist.com/blog/print/55671/_ 
(http://www.the-scientist.com/blog/print/55671/) 
 

Eli Lilly paid ghostwriters to push Zyprexa;  and Pfizer-funded 
ghostwriters generated 85 articles about Zoloft in the late  1990s, according 
to the 
British Journal of Psychiatry. [2]


Yet, no meaningful disciplinary action has been taken against anyone:  
academics continue to append their name to ghostwritten articles for cash;  
journals taken no steps to cleanse the medical-scientific literature of  
ghostwritten, hence, fraudulent articles; nor have steps even been taken to  
bring 
transparency to "peer review."


Our view that this is an endemic problem linked to industry's influence  on 
medicine, is corroborated by a spokesman for Wyeth who acknowledged that  
"pharmaceutical companies routinely hired medical writing companies to assist 
 authors in drafting manuscripts." When a High School student pens his name 
to an  article written by someone else, it's called cheating, earning the 
student an F  grade and precluding entry into a reputable college. 


Shouldn't we expect medical professionals at major academic  institutions 
to, at the very least, adhere to academic standards required of  High School 
students?


Dr. Daniel Carlat suggests that the proper collective response from all  of 
the participants in fraud should have been: "We sincerely apologize for  
having deceived the medical community by engaging in ghostwriting without  
disclosure. We have contributed to the erosion of the public's trust in  
medicine, and we regret it." See 
_HERE_ 
(http://carlatpsychiatry.blogspot.com/2009/08/ghostwriting-for-premarin-steroids-on.html)
    
_http://carlatpsychiatry.blogspot.com/2009/08/ghostwriting-for-premarin-ster
oids-on.html_ 
(http://carlatpsychiatry.blogspot.com/2009/08/ghostwriting-for-premarin-steroids-on.html)
 
 
 
References:
 

1. Flanagin A, Carey LA, Fontanarosa PB, Phillips SG, Pace BP, et  al.
(1998) Prevalence of articles with honorary authors and ghost authors in  
peer-reviewed medical journals. JAMA 280: 222-224. 

 
2. Healy D, Cattell D (2003) Interface between  authorship, industry and 
science in the domain of therapeutics. Br J Psychiatry  183: 22-27. 
 
 
Contact: Vera Hassner  Sharav
212-595-8974
[EMAIL PROTECTED] (mailto:[EMAIL PROTECTED]) 
 
 
 
THE NEW YORK TIMES
August 5,  2009
_Medical Papers by Ghostwriters Pushed  Therapy_ 
(http://www.nytimes.com/2009/08/05/health/research/05ghost.html?hp)  
By NATASHA  SINGER


 (http://www.papercut.biz/emailStripper.htm) 




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