moving apps in bluetooth.

2017-12-22 Thread Billy Inglis
hi guys, can a bluetooth keyboard be used to move apps on iphone5s?, and 
can the keyboard be also use for creating folders?, Billy


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Re: Attention to people with RP

2017-12-22 Thread Mohib Anwar Rafay
1 million? It would be out of reach of a person!

On 12/22/17, Dulce Muccio Weisenborn  wrote:
> NPR said perhaps one million for both eyes.
>
> -Original Message-
> From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf
> Of Mohib Anwar Rafay
> Sent: Friday, December 22, 2017 1:13 AM
> To: viphone@googlegroups.com
> Subject: Re: Attention to people with RP
>
> just wondering what will be the expensis incurred for this treatment?
>
> On 12/21/17, Marie  wrote:
>> I am including some information I received yesterday concerning a gene
>> therapy treatment which has been approved by the FDA for people with
>> Retinitis Pigmentosa. I am sending it to all the lists I currently belong
>> to
>> because it needs to get to as many RP sufferers as possible.
>> Marie
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>>
>> First Gene Therapy to Treat Blindness
>>
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring
>> treatment
>> for people with RPE65 mutations and will help advance other gene
>> therapies
>> currently in development.
>>
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval
>> of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing
>> for
>> patients with vision loss due to mutations in the RPE65 gene and a
>> watershed
>> moment for the inherited retinal disease field, says the Foundation
>> Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding for the therapy.
>>
>> The groundbreaking treatment is the first gene therapy for the eye and
>> for
>> any inherited disease to be approved by the FDA. The treatment restores
>> vision by delivering working copies of the RPE65 gene directly into the
>> retina, thereby compensating for the nonfunctional, mutated genes.
>>
>> “We are thrilled for the patients whose lives will change dramatically
>> because of this treatment,” says David Brint, Foundation Fighting
>> Blindness
>> chairman. “We are also pleased to have this concrete example of the
>> strength
>> of the Foundation’s strategy of identifying and investing early in
>> promising
>> treatments. Doing so helps attract industry investment that can usher
>> promising treatments through clinical trials and ultimately FDA
>> approval.”
>>
>> LUXTURNA is the result of more than two decades of research and
>> development
>> at the University of Florida, the University of Pennsylvania, Children’s
>> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
>> Blindness’ seed investment allowed researchers to take the therapy
>> through
>> the early investigational stages critical to any treatment development.
>>
>> “LUXTURNA will be life-changing for people with an inherited retinal
>> disease
>> caused by RPE65 mutations. For them, the treatment means alife of
>> independence. Also important is the momentum this approval provides to
>> other
>> gene-based therapies — for the eye and other diseases — now in the
>> clinic,”
>> says Benjamin Yerxa, PhD, Foundation CEO.
>>
>> An additional noteworthy milestone is the demonstrated value of a new
>> clinical endpoint devised by the Spark Therapeutics team to measure
>> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
>> (informally called the maze), measured the impact of the treatment beyond
>> the traditional visual acuity measure — the eye chart. This new clinical
>> endpoint moves vision measures beyond the eye chart, which is
>> particularly
>> significant for people with low or no vision.
>>
>> Spark Therapeutics, which holds the biologics license for LUXTURNA and
>> conducted the clinical trials that showed its safety and efficacy, will
>> also
>> manage the treatment rollout. Spark has announced that in order to ensure
>> the treatment is safely administered, it will only be available through a
>> small number of centers of clinical excellence across the country. Spark
>> has
>> also expressed its commitment to educating third-party payers about the
>> value of LUXTURNA and to working to help ensure treatment access to all
>> eligible patients.
>>
>> Anyone in need of more information about LUXTURNA should contact Spark
>> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
>> information is Spark’s website: www.Sparktx.com.
>>
>>
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>>
>> First Gene Therapy to Treat Blindness
>>
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring
>> treatment
>> for people with RPE65 mutations and will help advance other gene
>> therapies
>> currently in development.
>>
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval
>> of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing
>> for
>> patients with vision loss due to mutations in the RPE65 gene and a
>> 

Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread Mike Arrigo
While I'm not sure that it was an attempt by Apple to get people to 
purchase a newer model of phone, they should have disclosed that they 
were doing this when the update was released, or at least given the 
user a choice as to whether the phone would be slowed down, so Apple 
was not totally innocent here.

Original message:

Apple's iPhone slowdown sparks lawsuit alleging fraud
The plaintiffs contend that an Apple software tweak that slows down older
iPhones was a ploy to spur upgrades to pricier models.
December 22, 2017 8:25 AM PST



Apple disclosed Wednesday that it updated the software of older iPhones to
slow them down when the battery can't keep up with the phone's computer.
Sarah Tew/CNET
Apple's controversial iPhone slowdown is drawing legal fire.
A pending lawsuit against Apple says a software tweak that slows some older
iPhones to counteract problems found in aging batteries is a fraud designed
to spur upgrades to the latest model.
Apple didn't immediately respond to a message seeking comment.
After years of complaints from consumers that their iPhones seem slower once
a new model is released, Apple on Wednesday disclosed it was indeed slowing
the performance of some older iPhones under particular circumstances. When
batteries age, become very cold or operate at low power, their currents can
spike when the phone's computer tries to hit higher speeds. Rather than
having a phone shut down automatically to protect itself, Apple said that
last year it tweaked its iOS software for some older iPhones so they slow
down instead.
The lawsuit, filed Thursday in the Northern District of Illinois, Eastern
division, represents five people who claim the company purposefully updated
the phones' operating system to dampen its performance as a way of
"fraudulently forcing iPhone owners to purchase the latest model from
Apple," according to a release from attorney James Vlahakis of Lombard,
Illinois-based Atlas Consumer Law.
The plaintiffs allege this fraud applies to updates to the iPhone 5, iPhone
6 and certain iPhone 7 models.
Apple's disclosure this week didn't include the iPhone 5. The company said
the software update applied to the iPhone 6 and 6 Plus, 6S and 6S Plus and
SE, and earlier this year was extended to the iPhone 7 and 7 Plus. It will
be applied to other Apple devices in the future, the company said.
In the past, Apple has routinely said it doesn't purposely slow phones to
encourage customers to replace them. Apple said in a statement earlier this
week that the goal of the battery-related slowing was "to deliver the best
experience for customers."



Original Article at:
https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#ftag=C
AD-09-10aai5b




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Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread Andy Baracco
I think that it is simply a case of folks looking for money or some kind of 
freeby, like an upgrade to an iPhone 8 or 10. Also, there are lawyers who 
are always sniffing for blood in the water.


Andy

- Original Message - 
From: "Aleeha Dudley" 

To: 
Sent: Friday, December 22, 2017 11:27 AM
Subject: Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET


I’m sorry, but this sounds like a pile of crap to me. I would rather a 
company slow my device if the battery is unsafe than allow it to run at the 
same speed it would as new and then…. Samsung Note 7, anyone? All joking 
aside, I would rather have a safe, slower functioning product than one that 
shuts off at random times.

Aleeha


On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:

Apple's iPhone slowdown sparks lawsuit alleging fraud
The plaintiffs contend that an Apple software tweak that slows down older
iPhones was a ploy to spur upgrades to pricier models.
December 22, 2017 8:25 AM PST

Apple disclosed Wednesday that it updated the software of older iPhones to
slow them down when the battery can't keep up with the phone's computer.
Sarah Tew/CNET
Apple's controversial iPhone slowdown is drawing legal fire.
A pending lawsuit against Apple says a software tweak that slows some 
older
iPhones to counteract problems found in aging batteries is a fraud 
designed

to spur upgrades to the latest model.
Apple didn't immediately respond to a message seeking comment.
After years of complaints from consumers that their iPhones seem slower 
once
a new model is released, Apple on Wednesday disclosed it was indeed 
slowing

the performance of some older iPhones under particular circumstances. When
batteries age, become very cold or operate at low power, their currents 
can

spike when the phone's computer tries to hit higher speeds. Rather than
having a phone shut down automatically to protect itself, Apple said that
last year it tweaked its iOS software for some older iPhones so they slow
down instead.
The lawsuit, filed Thursday in the Northern District of Illinois, Eastern
division, represents five people who claim the company purposefully 
updated

the phones' operating system to dampen its performance as a way of
"fraudulently forcing iPhone owners to purchase the latest model from
Apple," according to a release from attorney James Vlahakis of Lombard,
Illinois-based Atlas Consumer Law.
The plaintiffs allege this fraud applies to updates to the iPhone 5, 
iPhone

6 and certain iPhone 7 models.
Apple's disclosure this week didn't include the iPhone 5. The company said
the software update applied to the iPhone 6 and 6 Plus, 6S and 6S Plus and
SE, and earlier this year was extended to the iPhone 7 and 7 Plus. It will
be applied to other Apple devices in the future, the company said.
In the past, Apple has routinely said it doesn't purposely slow phones to
encourage customers to replace them. Apple said in a statement earlier 
this

week that the goal of the battery-related slowing was "to deliver the best
experience for customers."

Original Article at:
https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#ftag=C
AD-09-10aai5b


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To 

Any one having issues signing into the new Skype version 8.12.2

2017-12-22 Thread Mr. Ed
Hi,

Has anyone had trouble signing into the new Skype version 8.12.2? 

If you can log in how is the new Skype?

Mr. Ed

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RE: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread M. Taylor
Hello Aleeha,

Of course, I agree with you but I think the issue is that Apple has been 
telling people that such a practice did not occur.  

It's the dishonesty that people take issue with.

Just be upfront with everyone, and most will appreciate the honesty.

Case in point, there is a software bug with iPhone 8 that, at present, only 
occurs on iPhone 8.  It is not a significant bug, but, a bug, nevertheless.

When I and many others asked Apple about this bug, they denied it even though, 
later, they acknowledged it.  

The problem is that they knew of the bug at the time when we all reported it.

I will not go into details of the bug, at this time but it's difficult not to 
get angry at a company that deliberately lies to its customers.

Just some food for thought, as it were.

Mark

-Original Message-
From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf Of 
Aleeha Dudley
Sent: Friday, December 22, 2017 11:27 AM
To: viphone@googlegroups.com
Subject: Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

I’m sorry, but this sounds like a pile of crap to me. I would rather a company 
slow my device if the battery is unsafe than allow it to run at the same speed 
it would as new and then…. Samsung Note 7, anyone? All joking aside, I would 
rather have a safe, slower functioning product than one that shuts off at 
random times.
Aleeha 

> On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:
> 
> Apple's iPhone slowdown sparks lawsuit alleging fraud The plaintiffs 
> contend that an Apple software tweak that slows down older iPhones was 
> a ploy to spur upgrades to pricier models.
> December 22, 2017 8:25 AM PST
> 
> Apple disclosed Wednesday that it updated the software of older 
> iPhones to slow them down when the battery can't keep up with the phone's 
> computer.
> Sarah Tew/CNET
> Apple's controversial iPhone slowdown is drawing legal fire. 
> A pending lawsuit against Apple says a software tweak that slows some 
> older iPhones to counteract problems found in aging batteries is a 
> fraud designed to spur upgrades to the latest model.
> Apple didn't immediately respond to a message seeking comment.  
> After years of complaints from consumers that their iPhones seem 
> slower once a new model is released, Apple on Wednesday disclosed it 
> was indeed slowing the performance of some older iPhones under 
> particular circumstances. When batteries age, become very cold or 
> operate at low power, their currents can spike when the phone's 
> computer tries to hit higher speeds. Rather than having a phone shut 
> down automatically to protect itself, Apple said that last year it 
> tweaked its iOS software for some older iPhones so they slow down instead.
> The lawsuit, filed Thursday in the Northern District of Illinois, 
> Eastern division, represents five people who claim the company 
> purposefully updated the phones' operating system to dampen its 
> performance as a way of "fraudulently forcing iPhone owners to 
> purchase the latest model from Apple," according to a release from 
> attorney James Vlahakis of Lombard, Illinois-based Atlas Consumer Law.
> The plaintiffs allege this fraud applies to updates to the iPhone 5, 
> iPhone
> 6 and certain iPhone 7 models.  
> Apple's disclosure this week didn't include the iPhone 5. The company 
> said the software update applied to the iPhone 6 and 6 Plus, 6S and 6S 
> Plus and SE, and earlier this year was extended to the iPhone 7 and 7 
> Plus. It will be applied to other Apple devices in the future, the company 
> said.
> In the past, Apple has routinely said it doesn't purposely slow phones 
> to encourage customers to replace them. Apple said in a statement 
> earlier this week that the goal of the battery-related slowing was "to 
> deliver the best experience for customers."
> 
> Original Article at:
> https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#
> ftag=C
> AD-09-10aai5b
> 
> 
> --
> The following information is important for all members of the V iPhone list.
> 
> If you have any questions or concerns about the running of this list, or if 
> you feel that a member's post is inappropriate, please contact the owners or 
> moderators directly rather than posting on the list itself.
> 
> Your V iPhone list moderator is Mark Taylor.  Mark can be reached at:  
> mk...@ucla.edu.  Your list owner is Cara Quinn - you can reach Cara at 
> caraqu...@caraquinn.com
> 
> The archives for this list can be searched at:
> http://www.mail-archive.com/viphone@googlegroups.com/
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The 

Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread Aleeha Dudley
The Samsung comment was merely a joke…. As I alluded to in the following 
sentence. I understand that it was a different situation, I was merely saying 
that without regulations on devices, as batteries get older, similar situations 
with overheating batteries could happen. 

> On Dec 22, 2017, at 2:51 PM, Cristóbal  wrote:
> 
> I don’t' know about the merits of these particular law suits, but you're 
> making a straw man argument. The Samsung problem had nothing to do with this. 
> Something entirely different.
> What people may argue and I may be inclined to agree with is by slowing 
> devices down, the manufacturer is not so subtly nudging folks into upgrading 
> their device when a less expensive option was available the entire time. I 
> mean pay $60 to $100 for a battery swap or $600 and up for a whole new phone?
> Sure, I guess some folks may go out and buy a whole new computer when their 
> PC begins to get all slow and buggy, but how many of us take the time to 
> first go through less expensive options first? Replace this or upgrade 
> components that or simply start from scratch by reformatting the machine all 
> together. 
> Besides, who's to say that Apple knows best on how you should use your 
> device? This will probably freak out libertarians to no end. 
> I will say, I just recently replaced the battery on my business 5S and while 
> it's still a four year old phone now, I have noticed an improvement in 
> overall snappiness with VoiceOver. I use it for the most basic of tasks. 
> Mainly making and receiving calls with maybe a few extra apps like a timer 
> for working out or cooking or Pandora, but all in all, improved battery 
> aside, VO and iOS performance isn't as sluggish. I have no need to replace or 
> upgrade my 5S and with my new battery, I can probably get some more good use 
> out of it now. I’m going to ride this bad boy until the wheels fall off.
> 
> -Original Message-
> From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf Of 
> Aleeha Dudley
> Sent: Friday, December 22, 2017 11:27 AM
> To: viphone@googlegroups.com
> Subject: Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET
> 
> I’m sorry, but this sounds like a pile of crap to me. I would rather a 
> company slow my device if the battery is unsafe than allow it to run at the 
> same speed it would as new and then…. Samsung Note 7, anyone? All joking 
> aside, I would rather have a safe, slower functioning product than one that 
> shuts off at random times.
> Aleeha 
> 
>> On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:
>> 
>> Apple's iPhone slowdown sparks lawsuit alleging fraud The plaintiffs 
>> contend that an Apple software tweak that slows down older iPhones was 
>> a ploy to spur upgrades to pricier models.
>> December 22, 2017 8:25 AM PST
>> 
>> Apple disclosed Wednesday that it updated the software of older 
>> iPhones to slow them down when the battery can't keep up with the phone's 
>> computer.
>> Sarah Tew/CNET
>> Apple's controversial iPhone slowdown is drawing legal fire. 
>> A pending lawsuit against Apple says a software tweak that slows some 
>> older iPhones to counteract problems found in aging batteries is a 
>> fraud designed to spur upgrades to the latest model.
>> Apple didn't immediately respond to a message seeking comment.  
>> After years of complaints from consumers that their iPhones seem 
>> slower once a new model is released, Apple on Wednesday disclosed it 
>> was indeed slowing the performance of some older iPhones under 
>> particular circumstances. When batteries age, become very cold or 
>> operate at low power, their currents can spike when the phone's 
>> computer tries to hit higher speeds. Rather than having a phone shut 
>> down automatically to protect itself, Apple said that last year it 
>> tweaked its iOS software for some older iPhones so they slow down instead.
>> The lawsuit, filed Thursday in the Northern District of Illinois, 
>> Eastern division, represents five people who claim the company 
>> purposefully updated the phones' operating system to dampen its 
>> performance as a way of "fraudulently forcing iPhone owners to 
>> purchase the latest model from Apple," according to a release from 
>> attorney James Vlahakis of Lombard, Illinois-based Atlas Consumer Law.
>> The plaintiffs allege this fraud applies to updates to the iPhone 5, 
>> iPhone
>> 6 and certain iPhone 7 models.  
>> Apple's disclosure this week didn't include the iPhone 5. The company 
>> said the software update applied to the iPhone 6 and 6 Plus, 6S and 6S 
>> Plus and SE, and earlier this year was extended to the iPhone 7 and 7 
>> Plus. It will be applied to other Apple devices in the future, the company 
>> said.
>> In the past, Apple has routinely said it doesn't purposely slow phones 
>> to encourage customers to replace them. Apple said in a statement 
>> earlier this week that the goal of the battery-related slowing was 

Re: help with iphone, audio description, movies

2017-12-22 Thread elayneh

after looking on the app store I can't find this app. help please


On 12/15/2017 9:50 AM, mi...@eastlink.ca wrote:

hi the app is cald acctiveview the new starwars is not on the app yet though. 
hth. from Mich.

From: Gianni
Sent: Friday, December 15, 2017 9:45 AM
To: viphone@googlegroups.com
Subject: iphone, audio description, movies

Hi,
I would like to go the movies, the new star wars is cool. But is there an app 
on the iphone that provides audio description?



Gianni


Skype: giannijuve
Sent from my iPhone


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RE: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread Cristóbal
I don’t' know about the merits of these particular law suits, but you're making 
a straw man argument. The Samsung problem had nothing to do with this. 
Something entirely different.
What people may argue and I may be inclined to agree with is by slowing devices 
down, the manufacturer is not so subtly nudging folks into upgrading their 
device when a less expensive option was available the entire time. I mean pay 
$60 to $100 for a battery swap or $600 and up for a whole new phone?
Sure, I guess some folks may go out and buy a whole new computer when their PC 
begins to get all slow and buggy, but how many of us take the time to first go 
through less expensive options first? Replace this or upgrade components that 
or simply start from scratch by reformatting the machine all together. 
Besides, who's to say that Apple knows best on how you should use your device? 
This will probably freak out libertarians to no end. 
I will say, I just recently replaced the battery on my business 5S and while 
it's still a four year old phone now, I have noticed an improvement in overall 
snappiness with VoiceOver. I use it for the most basic of tasks. Mainly making 
and receiving calls with maybe a few extra apps like a timer for working out or 
cooking or Pandora, but all in all, improved battery aside, VO and iOS 
performance isn't as sluggish. I have no need to replace or upgrade my 5S and 
with my new battery, I can probably get some more good use out of it now. I’m 
going to ride this bad boy until the wheels fall off.

-Original Message-
From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf Of 
Aleeha Dudley
Sent: Friday, December 22, 2017 11:27 AM
To: viphone@googlegroups.com
Subject: Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

I’m sorry, but this sounds like a pile of crap to me. I would rather a company 
slow my device if the battery is unsafe than allow it to run at the same speed 
it would as new and then…. Samsung Note 7, anyone? All joking aside, I would 
rather have a safe, slower functioning product than one that shuts off at 
random times.
Aleeha 

> On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:
> 
> Apple's iPhone slowdown sparks lawsuit alleging fraud The plaintiffs 
> contend that an Apple software tweak that slows down older iPhones was 
> a ploy to spur upgrades to pricier models.
> December 22, 2017 8:25 AM PST
> 
> Apple disclosed Wednesday that it updated the software of older 
> iPhones to slow them down when the battery can't keep up with the phone's 
> computer.
> Sarah Tew/CNET
> Apple's controversial iPhone slowdown is drawing legal fire. 
> A pending lawsuit against Apple says a software tweak that slows some 
> older iPhones to counteract problems found in aging batteries is a 
> fraud designed to spur upgrades to the latest model.
> Apple didn't immediately respond to a message seeking comment.  
> After years of complaints from consumers that their iPhones seem 
> slower once a new model is released, Apple on Wednesday disclosed it 
> was indeed slowing the performance of some older iPhones under 
> particular circumstances. When batteries age, become very cold or 
> operate at low power, their currents can spike when the phone's 
> computer tries to hit higher speeds. Rather than having a phone shut 
> down automatically to protect itself, Apple said that last year it 
> tweaked its iOS software for some older iPhones so they slow down instead.
> The lawsuit, filed Thursday in the Northern District of Illinois, 
> Eastern division, represents five people who claim the company 
> purposefully updated the phones' operating system to dampen its 
> performance as a way of "fraudulently forcing iPhone owners to 
> purchase the latest model from Apple," according to a release from 
> attorney James Vlahakis of Lombard, Illinois-based Atlas Consumer Law.
> The plaintiffs allege this fraud applies to updates to the iPhone 5, 
> iPhone
> 6 and certain iPhone 7 models.  
> Apple's disclosure this week didn't include the iPhone 5. The company 
> said the software update applied to the iPhone 6 and 6 Plus, 6S and 6S 
> Plus and SE, and earlier this year was extended to the iPhone 7 and 7 
> Plus. It will be applied to other Apple devices in the future, the company 
> said.
> In the past, Apple has routinely said it doesn't purposely slow phones 
> to encourage customers to replace them. Apple said in a statement 
> earlier this week that the goal of the battery-related slowing was "to 
> deliver the best experience for customers."
> 
> Original Article at:
> https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#
> ftag=C
> AD-09-10aai5b
> 
> 
> --
> The following information is important for all members of the V iPhone list.
> 
> If you have any questions or concerns about the running of this list, or if 
> you feel that a member's post is inappropriate, please contact the owners or 
> moderators directly rather than 

Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread GARY WILLIAMS
Me too 

Sent from my iPhone

> On Dec 22, 2017, at 2:27 PM, Aleeha Dudley  wrote:
> 
> I’m sorry, but this sounds like a pile of crap to me. I would rather a 
> company slow my device if the battery is unsafe than allow it to run at the 
> same speed it would as new and then…. Samsung Note 7, anyone? All joking 
> aside, I would rather have a safe, slower functioning product than one that 
> shuts off at random times.
> Aleeha 
> 
>> On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:
>> 
>> Apple's iPhone slowdown sparks lawsuit alleging fraud
>> The plaintiffs contend that an Apple software tweak that slows down older
>> iPhones was a ploy to spur upgrades to pricier models.
>> December 22, 2017 8:25 AM PST
>> 
>> Apple disclosed Wednesday that it updated the software of older iPhones to
>> slow them down when the battery can't keep up with the phone's computer. 
>> Sarah Tew/CNET 
>> Apple's controversial iPhone slowdown is drawing legal fire. 
>> A pending lawsuit against Apple says a software tweak that slows some older
>> iPhones to counteract problems found in aging batteries is a fraud designed
>> to spur upgrades to the latest model.  
>> Apple didn't immediately respond to a message seeking comment.  
>> After years of complaints from consumers that their iPhones seem slower once
>> a new model is released, Apple on Wednesday disclosed it was indeed slowing
>> the performance of some older iPhones under particular circumstances. When
>> batteries age, become very cold or operate at low power, their currents can
>> spike when the phone's computer tries to hit higher speeds. Rather than
>> having a phone shut down automatically to protect itself, Apple said that
>> last year it tweaked its iOS software for some older iPhones so they slow
>> down instead.  
>> The lawsuit, filed Thursday in the Northern District of Illinois, Eastern
>> division, represents five people who claim the company purposefully updated
>> the phones' operating system to dampen its performance as a way of
>> "fraudulently forcing iPhone owners to purchase the latest model from
>> Apple," according to a release from attorney James Vlahakis of Lombard,
>> Illinois-based Atlas Consumer Law. 
>> The plaintiffs allege this fraud applies to updates to the iPhone 5, iPhone
>> 6 and certain iPhone 7 models.  
>> Apple's disclosure this week didn't include the iPhone 5. The company said
>> the software update applied to the iPhone 6 and 6 Plus, 6S and 6S Plus and
>> SE, and earlier this year was extended to the iPhone 7 and 7 Plus. It will
>> be applied to other Apple devices in the future, the company said. 
>> In the past, Apple has routinely said it doesn't purposely slow phones to
>> encourage customers to replace them. Apple said in a statement earlier this
>> week that the goal of the battery-related slowing was "to deliver the best
>> experience for customers." 
>> 
>> Original Article at:
>> https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#ftag=C
>> AD-09-10aai5b
>> 
>> 
>> -- 
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>> 
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> 
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Re: Really confused about how to move apps now since updating to iOS 11

2017-12-22 Thread 'Carol Pearson' via VIPhone
Yes, Mary, I found it pretty baffling at first but now really like it 
and use with ease.


You will get there, honestly.

Perhaps you could try to write down your steps and we could look at 
what's going wrong.


I certainly was sometimes trying to do the old way with the double tap 
and hold.


I hope you sort it soon but do come back if you still have problems. I 
found it infuriating that I couldn't do this basic task for a few days.


Happy Christmas to you and all!

Carol P - UK

On 11/2/2017 5:17 AM, Sieghard Weitzel wrote:


Hi Mary,

It sounds like you go on the app you want to move, start editing mode 
but then right away go to the folder where you want to put the app. 
You forget the one step which is after you start editing mode and 
while you are still focused on the app you want to move you flick down 
to drag and double tap that.


As somebody pointed out, in iOS 10 this used to be called “Move”, the 
nice thing is that in iOS 11 you can drag/move multiple apps at once. 
After you start editing mode and have focus on the first app flick to 
Drag and double tap, now go to another app you want to move or maybe 
you want to create a new folder and also flick down to Drag and double 
tap. Each time you do this Voiceover says you added this to the drag 
session and once you have all the apps marked, now go to the folder 
you want to add them to, flick to Add to Folder and double tap.


It works like a charm and I have not heard anybody say it wasn’t 
working and now in iOS 11.1 the “edit” option is there again, prior to 
11.1 you had to double tap and hold on an app like in the old days and 
now with devices which support 3D Touch quite a few people who maybe 
tend to tap their screen quite hard had problems with this because 
instead of starting editing mode they would invoke the 3D Touch 
shortcut menu.


*From:* viphone@googlegroups.com [mailto:viphone@googlegroups.com] *On 
Behalf Of *Mary Otten

*Sent:* Wednesday, November 1, 2017 8:46 PM
*To:* viphone@googlegroups.com
*Subject:* Re: Really confused about how to move apps now since 
updating to iOS 11


 The problem seems to be that once I put focus on the News folder, the 
ad to folder thing just isn’t there. I get an option to add the folder 
to the drag session, which I certainly don’t want to do. It’s just 
screwed up.

Mary

Sent from my iPhone


On Nov 1, 2017, at 7:33 PM, Richard Turner 
> wrote:


Hi Mary,

Drag is the new move.

So, flick to drag after you start editing and double tap.

Then, go to the folder you want to drop it into and flick down
until you get to add newsline to folder.

Then you may here "drop ready" and then double tap and it should work.

HTH,

Richard



(Sent from the iPod Touch 6)


On Nov 1, 2017, at 7:18 PM, Mary Otten > wrote:

I am thoroughly confused as to how I move apps now since I
updated. I wanted to get the NFB-Newsline into my News folder.
So I started edit mode. But then when I flick all I see is
drag. But double tapping and trying to move doesn’t get the
job done. What the heck are you supposed to do to move file
into a folder. Color me confused.

Sent from my iPhone

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Re: Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread Aleeha Dudley
I’m sorry, but this sounds like a pile of crap to me. I would rather a company 
slow my device if the battery is unsafe than allow it to run at the same speed 
it would as new and then…. Samsung Note 7, anyone? All joking aside, I would 
rather have a safe, slower functioning product than one that shuts off at 
random times.
Aleeha 

> On Dec 22, 2017, at 1:41 PM, M. Taylor  wrote:
> 
> Apple's iPhone slowdown sparks lawsuit alleging fraud
> The plaintiffs contend that an Apple software tweak that slows down older
> iPhones was a ploy to spur upgrades to pricier models.
> December 22, 2017 8:25 AM PST
> 
> Apple disclosed Wednesday that it updated the software of older iPhones to
> slow them down when the battery can't keep up with the phone's computer. 
> Sarah Tew/CNET 
> Apple's controversial iPhone slowdown is drawing legal fire. 
> A pending lawsuit against Apple says a software tweak that slows some older
> iPhones to counteract problems found in aging batteries is a fraud designed
> to spur upgrades to the latest model.  
> Apple didn't immediately respond to a message seeking comment.  
> After years of complaints from consumers that their iPhones seem slower once
> a new model is released, Apple on Wednesday disclosed it was indeed slowing
> the performance of some older iPhones under particular circumstances. When
> batteries age, become very cold or operate at low power, their currents can
> spike when the phone's computer tries to hit higher speeds. Rather than
> having a phone shut down automatically to protect itself, Apple said that
> last year it tweaked its iOS software for some older iPhones so they slow
> down instead.  
> The lawsuit, filed Thursday in the Northern District of Illinois, Eastern
> division, represents five people who claim the company purposefully updated
> the phones' operating system to dampen its performance as a way of
> "fraudulently forcing iPhone owners to purchase the latest model from
> Apple," according to a release from attorney James Vlahakis of Lombard,
> Illinois-based Atlas Consumer Law. 
> The plaintiffs allege this fraud applies to updates to the iPhone 5, iPhone
> 6 and certain iPhone 7 models.  
> Apple's disclosure this week didn't include the iPhone 5. The company said
> the software update applied to the iPhone 6 and 6 Plus, 6S and 6S Plus and
> SE, and earlier this year was extended to the iPhone 7 and 7 Plus. It will
> be applied to other Apple devices in the future, the company said. 
> In the past, Apple has routinely said it doesn't purposely slow phones to
> encourage customers to replace them. Apple said in a statement earlier this
> week that the goal of the battery-related slowing was "to deliver the best
> experience for customers." 
> 
> Original Article at:
> https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#ftag=C
> AD-09-10aai5b
> 
> 
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Re: Amazon Prime Video voice and audio description

2017-12-22 Thread bpabbott9
. I’m just curious whether or not audio description is available in Canada.

I have not been able to turn it on either using my iPhone or my computer or 
even getting cited help. I called Amazon about the problem and they are 
supposed to be calling me back I know that the show Bosch is supposed to be 
described and I know that the audio description is supposed to be found under 
subtitles and audio however it does not seem to show up in any of my devices. 
When I try running Bosch I am not getting the audio description.

I’m wondering if anybody can tell me whether it is or is not available in 
Canada thanks for this and to everyone have a wonderful holiday.

Barry

Sent from Bäry Abbott's  iPhone

> On Dec 21, 2017, at 3:42 PM, Aleeha Dudley  wrote:
> 
> Hi, 
> Assuming you’re talking about Apple TV, there is no way to disable the text 
> to speech that Amazon provides. I find it somewhat annoying.
> Not sure about your audio description question, as I don’t use Prime video 
> all that much.
> Aleeha 
> 
>> On Dec 21, 2017, at 11:00 AM, Tom Rash  wrote:
>> 
>> Is there anyway to turn off Prime Video’s voice?  She talks over the 
>> beginning of the movie.  Also anyone having trouble with audio description?  
>> Sometimes I have to turn it on for each episode.  I can’t read those 
>> settings with voice over or the Prime Video voice.
>>  
>>  
>> 
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Apple's iPhone slowdown sparks fraud lawsuit - CNET

2017-12-22 Thread M. Taylor
Apple's iPhone slowdown sparks lawsuit alleging fraud
The plaintiffs contend that an Apple software tweak that slows down older
iPhones was a ploy to spur upgrades to pricier models.
December 22, 2017 8:25 AM PST
 
Apple disclosed Wednesday that it updated the software of older iPhones to
slow them down when the battery can't keep up with the phone's computer. 
Sarah Tew/CNET 
Apple's controversial iPhone slowdown is drawing legal fire. 
A pending lawsuit against Apple says a software tweak that slows some older
iPhones to counteract problems found in aging batteries is a fraud designed
to spur upgrades to the latest model.  
Apple didn't immediately respond to a message seeking comment.  
After years of complaints from consumers that their iPhones seem slower once
a new model is released, Apple on Wednesday disclosed it was indeed slowing
the performance of some older iPhones under particular circumstances. When
batteries age, become very cold or operate at low power, their currents can
spike when the phone's computer tries to hit higher speeds. Rather than
having a phone shut down automatically to protect itself, Apple said that
last year it tweaked its iOS software for some older iPhones so they slow
down instead.  
The lawsuit, filed Thursday in the Northern District of Illinois, Eastern
division, represents five people who claim the company purposefully updated
the phones' operating system to dampen its performance as a way of
"fraudulently forcing iPhone owners to purchase the latest model from
Apple," according to a release from attorney James Vlahakis of Lombard,
Illinois-based Atlas Consumer Law. 
The plaintiffs allege this fraud applies to updates to the iPhone 5, iPhone
6 and certain iPhone 7 models.  
Apple's disclosure this week didn't include the iPhone 5. The company said
the software update applied to the iPhone 6 and 6 Plus, 6S and 6S Plus and
SE, and earlier this year was extended to the iPhone 7 and 7 Plus. It will
be applied to other Apple devices in the future, the company said. 
In the past, Apple has routinely said it doesn't purposely slow phones to
encourage customers to replace them. Apple said in a statement earlier this
week that the goal of the battery-related slowing was "to deliver the best
experience for customers." 

Original Article at:
https://www.cnet.com/news/apple-iphone-slowdown-sparks-fraud-lawsuit/#ftag=C
AD-09-10aai5b


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Re: T9 keyboard

2017-12-22 Thread 'Carol Pearson' via VIPhone
Yes, I'm going to do that during my break away from home, when I'm 
playing around but using my phone to good effect.


Thanks.

Carol P - UK

On 10/19/2017 12:50 AM, Michael Maslo wrote:

Hello

There are no real gestures per say. There are three finger gestures. 
 three finger down and up which go through the choices of words 
available. If you ever used the old fashion t9 keyboard on the old 
phones it is based upon that. Once you get used of it you would like 
it a lot. I wish I could explain it better. My suggestion is to try it 
for yourself and see for yourself.  Oct 18, 2017 at 15:06, <'Carol 
Pearson' via VIPhone > wrote:


I looked at it in the App Store but wasn't quite sure how difficult it was for 
someone who can't see at all  Can anyone give me any idea of some of the 
gestures that you have to use. That might be useful to me



Carol P
Sent from my iPhone using MBraille

On 18 Oct 2017, at 8:57 pm, christopher hallsworth  wrote:

Hello, same here, the app's official name is "Type Nine", and is a few bucks, 
but well worth it. And yes, the VoiceOver improvements in the latest update is wonderful.

> On 16 Oct 2017, at 22:38, Michael Maslo  wrote:
>
> Hi list,
>
> I wanted to make people awareOf a keyboard which was discussed on list 
before. It is called t9 keyboard. They have had a update and it has made it more 
accessible with voice over. Using this keyboard I can type faster than I ever 
typed before. It is using the old t9 method of typing but a lot faster and easier 
to use. I really like it a lot and recommend it a lot.
>
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RE: Attention to people with RP

2017-12-22 Thread Dulce Muccio Weisenborn
NPR said perhaps one million for both eyes.

-Original Message-
From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf Of 
Mohib Anwar Rafay
Sent: Friday, December 22, 2017 1:13 AM
To: viphone@googlegroups.com
Subject: Re: Attention to people with RP

just wondering what will be the expensis incurred for this treatment?

On 12/21/17, Marie  wrote:
> I am including some information I received yesterday concerning a gene
> therapy treatment which has been approved by the FDA for people with
> Retinitis Pigmentosa. I am sending it to all the lists I currently belong to
> because it needs to get to as many RP sufferers as possible.
> Marie
> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>
> First Gene Therapy to Treat Blindness
>
> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
> for people with RPE65 mutations and will help advance other gene therapies
> currently in development.
>
> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval of
> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing for
> patients with vision loss due to mutations in the RPE65 gene and a watershed
> moment for the inherited retinal disease field, says the Foundation Fighting
> Blindness. The Foundation was an important early investor in LUXTURNA,
> providing $10 million in critical seed funding for the therapy.
>
> The groundbreaking treatment is the first gene therapy for the eye and for
> any inherited disease to be approved by the FDA. The treatment restores
> vision by delivering working copies of the RPE65 gene directly into the
> retina, thereby compensating for the nonfunctional, mutated genes.
>
> “We are thrilled for the patients whose lives will change dramatically
> because of this treatment,” says David Brint, Foundation Fighting Blindness
> chairman. “We are also pleased to have this concrete example of the strength
> of the Foundation’s strategy of identifying and investing early in promising
> treatments. Doing so helps attract industry investment that can usher
> promising treatments through clinical trials and ultimately FDA approval.”
>
> LUXTURNA is the result of more than two decades of research and development
> at the University of Florida, the University of Pennsylvania, Children’s
> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
> Blindness’ seed investment allowed researchers to take the therapy through
> the early investigational stages critical to any treatment development.
>
> “LUXTURNA will be life-changing for people with an inherited retinal disease
> caused by RPE65 mutations. For them, the treatment means alife of
> independence. Also important is the momentum this approval provides to other
> gene-based therapies — for the eye and other diseases — now in the clinic,”
> says Benjamin Yerxa, PhD, Foundation CEO.
>
> An additional noteworthy milestone is the demonstrated value of a new
> clinical endpoint devised by the Spark Therapeutics team to measure
> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
> (informally called the maze), measured the impact of the treatment beyond
> the traditional visual acuity measure — the eye chart. This new clinical
> endpoint moves vision measures beyond the eye chart, which is particularly
> significant for people with low or no vision.
>
> Spark Therapeutics, which holds the biologics license for LUXTURNA and
> conducted the clinical trials that showed its safety and efficacy, will also
> manage the treatment rollout. Spark has announced that in order to ensure
> the treatment is safely administered, it will only be available through a
> small number of centers of clinical excellence across the country. Spark has
> also expressed its commitment to educating third-party payers about the
> value of LUXTURNA and to working to help ensure treatment access to all
> eligible patients.
>
> Anyone in need of more information about LUXTURNA should contact Spark
> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
> information is Spark’s website: www.Sparktx.com.
>
>
> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>
> First Gene Therapy to Treat Blindness
>
> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
> for people with RPE65 mutations and will help advance other gene therapies
> currently in development.
>
> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval of
> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing for
> patients with vision loss due to mutations in the RPE65 gene and a watershed
> moment for the inherited retinal disease field, says the Foundation Fighting
> Blindness. The Foundation was an important early investor in LUXTURNA,
> providing $10 million in critical seed funding for the therapy.
>
> The groundbreaking treatment is the first gene therapy for the 

RE: Attention to people with RP

2017-12-22 Thread Dulce Muccio Weisenborn

FDA just approved the gene-editing procedure.  The company will name its price 
in January, which is thought to be a million dollars for both eyes.
-Original Message-
From: viphone@googlegroups.com [mailto:viphone@googlegroups.com] On Behalf Of 
Deidre Muccio
Sent: Friday, December 22, 2017 7:02 AM
To: viphone@googlegroups.com
Subject: Re: Attention to people with RP

Sparks therapeutics? I don't see any big-name research hospitals like Johns 
Hopkins or other retina foundation based clinics. Little strange. No technical 
details here.

Deidre


> On Dec 22, 2017, at 1:13 AM, Mohib Anwar Rafay  wrote:
> 
> just wondering what will be the expensis incurred for this treatment?
> 
>> On 12/21/17, Marie  wrote:
>> I am including some information I received yesterday concerning a gene
>> therapy treatment which has been approved by the FDA for people with
>> Retinitis Pigmentosa. I am sending it to all the lists I currently belong to
>> because it needs to get to as many RP sufferers as possible.
>> Marie
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>> 
>> First Gene Therapy to Treat Blindness
>> 
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
>> for people with RPE65 mutations and will help advance other gene therapies
>> currently in development.
>> 
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing for
>> patients with vision loss due to mutations in the RPE65 gene and a watershed
>> moment for the inherited retinal disease field, says the Foundation Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding for the therapy.
>> 
>> The groundbreaking treatment is the first gene therapy for the eye and for
>> any inherited disease to be approved by the FDA. The treatment restores
>> vision by delivering working copies of the RPE65 gene directly into the
>> retina, thereby compensating for the nonfunctional, mutated genes.
>> 
>> “We are thrilled for the patients whose lives will change dramatically
>> because of this treatment,” says David Brint, Foundation Fighting Blindness
>> chairman. “We are also pleased to have this concrete example of the strength
>> of the Foundation’s strategy of identifying and investing early in promising
>> treatments. Doing so helps attract industry investment that can usher
>> promising treatments through clinical trials and ultimately FDA approval.”
>> 
>> LUXTURNA is the result of more than two decades of research and development
>> at the University of Florida, the University of Pennsylvania, Children’s
>> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
>> Blindness’ seed investment allowed researchers to take the therapy through
>> the early investigational stages critical to any treatment development.
>> 
>> “LUXTURNA will be life-changing for people with an inherited retinal disease
>> caused by RPE65 mutations. For them, the treatment means alife of
>> independence. Also important is the momentum this approval provides to other
>> gene-based therapies — for the eye and other diseases — now in the clinic,”
>> says Benjamin Yerxa, PhD, Foundation CEO.
>> 
>> An additional noteworthy milestone is the demonstrated value of a new
>> clinical endpoint devised by the Spark Therapeutics team to measure
>> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
>> (informally called the maze), measured the impact of the treatment beyond
>> the traditional visual acuity measure — the eye chart. This new clinical
>> endpoint moves vision measures beyond the eye chart, which is particularly
>> significant for people with low or no vision.
>> 
>> Spark Therapeutics, which holds the biologics license for LUXTURNA and
>> conducted the clinical trials that showed its safety and efficacy, will also
>> manage the treatment rollout. Spark has announced that in order to ensure
>> the treatment is safely administered, it will only be available through a
>> small number of centers of clinical excellence across the country. Spark has
>> also expressed its commitment to educating third-party payers about the
>> value of LUXTURNA and to working to help ensure treatment access to all
>> eligible patients.
>> 
>> Anyone in need of more information about LUXTURNA should contact Spark
>> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
>> information is Spark’s website: www.Sparktx.com.
>> 
>> 
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>> 
>> First Gene Therapy to Treat Blindness
>> 
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
>> for people with RPE65 mutations and will help advance other gene therapies
>> currently in development.
>> 
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration 

Re: Attention to people with RP

2017-12-22 Thread Deidre Muccio
Sparks therapeutics? I don't see any big-name research hospitals like Johns 
Hopkins or other retina foundation based clinics. Little strange. No technical 
details here.

Deidre


> On Dec 22, 2017, at 1:13 AM, Mohib Anwar Rafay  wrote:
> 
> just wondering what will be the expensis incurred for this treatment?
> 
>> On 12/21/17, Marie  wrote:
>> I am including some information I received yesterday concerning a gene
>> therapy treatment which has been approved by the FDA for people with
>> Retinitis Pigmentosa. I am sending it to all the lists I currently belong to
>> because it needs to get to as many RP sufferers as possible.
>> Marie
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>> 
>> First Gene Therapy to Treat Blindness
>> 
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
>> for people with RPE65 mutations and will help advance other gene therapies
>> currently in development.
>> 
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing for
>> patients with vision loss due to mutations in the RPE65 gene and a watershed
>> moment for the inherited retinal disease field, says the Foundation Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding for the therapy.
>> 
>> The groundbreaking treatment is the first gene therapy for the eye and for
>> any inherited disease to be approved by the FDA. The treatment restores
>> vision by delivering working copies of the RPE65 gene directly into the
>> retina, thereby compensating for the nonfunctional, mutated genes.
>> 
>> “We are thrilled for the patients whose lives will change dramatically
>> because of this treatment,” says David Brint, Foundation Fighting Blindness
>> chairman. “We are also pleased to have this concrete example of the strength
>> of the Foundation’s strategy of identifying and investing early in promising
>> treatments. Doing so helps attract industry investment that can usher
>> promising treatments through clinical trials and ultimately FDA approval.”
>> 
>> LUXTURNA is the result of more than two decades of research and development
>> at the University of Florida, the University of Pennsylvania, Children’s
>> Hospital of Philadelphia, and Spark Therapeutics. The Foundation Fighting
>> Blindness’ seed investment allowed researchers to take the therapy through
>> the early investigational stages critical to any treatment development.
>> 
>> “LUXTURNA will be life-changing for people with an inherited retinal disease
>> caused by RPE65 mutations. For them, the treatment means alife of
>> independence. Also important is the momentum this approval provides to other
>> gene-based therapies — for the eye and other diseases — now in the clinic,”
>> says Benjamin Yerxa, PhD, Foundation CEO.
>> 
>> An additional noteworthy milestone is the demonstrated value of a new
>> clinical endpoint devised by the Spark Therapeutics team to measure
>> LUXTURNA’s impact. The new measure, a multi-luminance mobility test
>> (informally called the maze), measured the impact of the treatment beyond
>> the traditional visual acuity measure — the eye chart. This new clinical
>> endpoint moves vision measures beyond the eye chart, which is particularly
>> significant for people with low or no vision.
>> 
>> Spark Therapeutics, which holds the biologics license for LUXTURNA and
>> conducted the clinical trials that showed its safety and efficacy, will also
>> manage the treatment rollout. Spark has announced that in order to ensure
>> the treatment is safely administered, it will only be available through a
>> small number of centers of clinical excellence across the country. Spark has
>> also expressed its commitment to educating third-party payers about the
>> value of LUXTURNA and to working to help ensure treatment access to all
>> eligible patients.
>> 
>> Anyone in need of more information about LUXTURNA should contact Spark
>> Therapeutics at 1-833-SPARK-PS (833-772-7577). Another resource for
>> information is Spark’s website: www.Sparktx.com.
>> 
>> 
>> Foundation Fighting Blindness Celebrates Historic FDA Approval of
>> 
>> First Gene Therapy to Treat Blindness
>> 
>> Foundation’s early investment in LUXTURNA™ boosts vision-restoring treatment
>> for people with RPE65 mutations and will help advance other gene therapies
>> currently in development.
>> 
>> (Columbia, MD) — Today’s U.S. Food and Drug Administration (FDA) approval of
>> voretigene neparvovec, to be marketed as LUXTURNA, will be life-changing for
>> patients with vision loss due to mutations in the RPE65 gene and a watershed
>> moment for the inherited retinal disease field, says the Foundation Fighting
>> Blindness. The Foundation was an important early investor in LUXTURNA,
>> providing $10 million in critical seed funding