The Department of Biomolecular Mechanisms at the Max Planck Institute
for Medical Research in Heidelberg invites people interested in the
structure and dynamics of macromolecular switches and assemblies to
apply for
doctoral degree (Ph.D.) positions (reference number 13/2008) and
Hi Mo,
Phaser sometimes rejects solutions because of clashes in the crystal
packing, which may be due to differences between the search model and
the target molecule. I would certainly recommend to play around with the
PACK keyword to see whether Phaser will find solutions if more clashes
are
Dear David,
You can use ARP/wARP 7.0.1 (www.arp-warp.org), which should be better
than old arp_waters. Either the ARP/wARP GUI module 'ARP solvent' or a
command line script auto_solvent.sh
Best regards,
Victor
David J. Schuller wrote:
I note that in CCP4 6.1.0, arp_waters has been
There might be people who are interested in this but have not seen it
advertised: there is still place available at a not-too-expensive
fragment-based drug design meeting organised by the Royal Society of Chemistry.
It takes place March 4th and 5th at our place (AstraZeneca, Alderley Park,
We are looking to buy a polarizing filter for our Leica
stereomicroscope that we use to observe crystals. However, I am a
little confused about the types of filters that are available from
photography stores; specifically there are linear and circular
polarizers. I would guess that what I
Edmunds Optics and Prinz sell linear polarizers
of nearly any thread type/combination, as well as unmounted.
Probably cheaper than Leica.
Perhaps search the Edmunds site
http://www.edmundoptics.com/onlinecatalog/browse.cfm?categoryid=166
BR
From: CCP4 bulletin board
CCP4 bulletin board CCP4BB@JISCMAIL.AC.UK wrote on 01/21/2009 05:50:13
PM:
Hi there,
*warning, reading beyond this line might expose you to non CCP4
related topics*
anybody out there who could do the following experiment:
Turn on your microscope and measure the temperature after 30 minutes
Jurgen,
From your question I assume that you are having problems with the
warming up of the crystal tray due to the microscope light.
Did you consider the use of an external cold light source like the
KL1500 LCD?
I do not feel anything warming up.
Which microscope are you using?
The LED
Hi Terje,
I think the circular polarizers are really linear polarizers with a 1/4-wave
retarder (which make the polarized light circular again) sticked to the back.
The reason for them selling the CPs these days is because that digital cameras
will have problem metering with LPs. But for
Dear Jürgen,
Unless you have to spend your money on a microscope immedeately, it is best
to evaluate demo instruments from different vendors on site at the same
time. All vendors will give you a demo instrument for a few hours to
several days.
The new Olympus LED instruments are excellent
Here are some numbers
Matthew.Franklin:
Okay.
Start: 71.9 F
Finish: 73.1 F
Temperature measured with thermocouple Scotch-taped to the center of
the
microscope stage, underneath an empty 96-well plate. Room
thermostat set
to 70.
I should have mentioned that I was thinking about
We have tested the Zeiss LED plate with hanging and sitting drop trays
and found it it unsuitable for looking at crystals. The reason is the
really low contrast with this kind of diffuse illumination. Obviously,
contrast is generated by refraction at crystal/mother liquor
interfaces and
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