Dear Ritcha,
You could also try low molecular weight PEG's, e.g. PEG400 in fairly
high concentrations. They often do a good job in solubilizing ligands
and are usually much more crystal-friendly than e.g. DMSO.
Best,
Herman
-Original Message-
From: CCP4 bulletin board
On Fri, 2011-09-16 at 06:37 -0700, William G. Scott wrote:
If you update to 10.7, keep a clone of 10.6 just in case it drives you nuts.
There are all sorts of perverse changes, and (unlike the reversal in
scrolling direction) not a lot of over-ride options.
I guess this is one of them:
I've bitched enough about all things Mac, but this one's just too good
to pass on (from the article that Peter linked to):
The fundamental issue here is Lion's assumption that you don't know
what you're doing, and it's going to ensure you're protected from
cock-ups that, in your ignorance,
Crystal structure of a monomeric retroviral protease solved by protein
folding game players
The paper (Nature SB):
http://www.cs.washington.edu/homes/zoran/NSMBfoldit-2011.pdf
The game:
http://fold.it/portal/
Great! Maybe, they should add an extra term for correlation of Fcalc to
Fobs (or LLG or R) to their game. I wonder, if structures could be
solved ab inition by players, then :-).
Best regards,
Dirk.
Am 19.09.11 12:33, schrieb Kevin Cowtan:
Crystal structure of a monomeric retroviral protease
On Mon, Sep 19, 2011 at 6:39 AM, Dirk Kostrewa
kostr...@genzentrum.lmu.dewrote:
Great! Maybe, they should add an extra term for correlation of Fcalc to
Fobs (or LLG or R) to their game. I wonder, if structures could be solved ab
inition by players, then :-).
Actually, Kam Zhang's group did
Listening to Jobs speak recently, I got the distinct impression that the end of
the era of general desktop computers PC's may be on the horizon. Of course
that's iPad sales rhetoric, but it may be that the public moves away from
general computers and that surely will have implications for
First the C2221 cell is a version of the hexagonal with the 2-fold axes
now aligned along the a=b 2-fold in the hexagonal.
But I dont think you can define NCS properly without some knowledge of
coordinates.
If you have enough anomalous scatterers that might allow you to get a
start.
Does
Of course this has to be the case. I think most of us walk around with with
mobile phones that have memory and processing power more powerful than all of
the computers available before 1990.
Some of the things that seem difficult in Lion and are nanny-state-ish such as
automatic file
That's progress! A century ago we'd need an infinite amount of monkeys
typing on an infinite amount of typewriters to produce a single paper. Now
we need just a finite amount of gamers to produce 7+ models to get one
that looks quite like a folded protein. And it saved an heavy atom soak as
Hi Christine
As Nagarajan mentioned, we do have a UV Pen that we offer at a reasonably
modest price.
However we have not been promoting it because we've been struggling to find
a camera that we can recommend to use with it.
We use it with an old Russian microscope (normal glass optics) and a
On Mon, 2011-09-19 at 14:39 +0300, Adrian Goldman wrote:
Of course this has to be the case. I think most of us walk around with with
mobile phones that have memory and processing power more powerful than all of
the computers available before 1990.
Some of the things that seem difficult in
A postdoctoral research post is available to undertake translational structural
biology work on a kinase target within my research group in the Department of
Biochemistry. My group is located in the state-of-the-art Henry Wellcome
Building with access to excellent facilities for biochemical
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