Thanks for the all the comments on/off board. Especially for papers describing
this method as it may be handy if the structure is solved. The crystals are
reproducible. They have started to appear after 4 days. I can accelerate it to
a day using just 1.5M NaCl as a reservoir solution, though I
Dear Protein Crystallographers
We again invite proposals for performing crystal-based fragment
screening at Diamond's XChem facility at beamline I04-1, for the next
allocation period (Oct 2017 to April 2018).
*The deadline for proposals is SATURDAY 1st APRIL 5PM.*
*Details of how to
Dear CCP4bb members,
My apologies for posting non crystallography question. This relates to
protein aggregation thus I thought of asking to the board members
experienced in this.
I am working on an Antibody-small molecule conjugation which involves NHS
mediated coupling.
Upon conjugation I've
Details below of a position now open in my lab as part of a project to design
and test inhibitors of protein-protein interactions.
Please Email me with any informal enquiries.
Research Fellow in Structural Molecular Biology
Are you looking to apply your skills in Structural Biology to the
Dear all
First of all, thanks for the replies here and off-list. I reprocessed the data
to 2 A, and modeled two copies of the ligand in each of the two protein NCS
molecules, without using NCS restraints for refinement. I also calculated an SA
omit map and a polder map. In the end, the ligand
