Re: [ccp4bb] Issues with latest XDS (20171218)

Thank you Kay! Speaking as a beamline scientist I agree that the instrument should be set up right and things like the distance, beam center, and various angles should be known. However, also speaking as a beamline scientist I feel I should point out that EVERY instrument goes through at

[ccp4bb] cryoNET inaugural symposia

Dear colleagues, I am sending this email to call your atention about the cryoNET inaugural symposia (8-9 Oct 2018) in Copenhagen. CryoNET is a Nordic network in Cryo-electron microscopy that is funded by The Novo Nordisk Foundation in Denmark and the Knut and Alice Wallenberg Foundation in

Re: [ccp4bb] definition of "apo" and alternatives?

Just to make sure: The provided definitions are narrowly specific to *enzymes* - it was not specified what protein evoked the critique. In other cases of apo-use, example apolipoproteins, they are neither enzymes not is the lipid particle what one would commonly associate with a ligand or

Re: [ccp4bb] definition of "apo" and alternatives?

See also the IUPAC reccomandations : https://goldbook.iupac.org/html/A/A00417.html https://goldbook.iupac.org/html/H/H02836.html --- Stefano Trapani Maître de Conférences http://www.cbs.cnrs.fr/index.php/fr/personnel?PERS=Stefano%20Trapani - Centre de

Re: [ccp4bb] definition of "apo" and alternatives?

Hi Johannes, this is normal textbook knowledge, which got perverted over time and misusage. Just check with a serious dictionary like Merrian Webster or even the Wikipedia (see below). Best regards, Xavier https://www.merriam-webster.com/dictionary/apoenzyme

[ccp4bb] definition of "apo" and alternatives?

Dear collegues, a while ago, there was a discussion in the board on the term apo-structure as a way to descibe a native, free, or unbound protein (no ligands). I think the conclusion was that an apo-form is a halo enzyme lacking a cofactor and should not be used as a substitute for "unbound". We

[ccp4bb] Structural Biologist position at Morphic Therapeutic

Please apply directly through our website: https://morphictx.com/careers/opportunities/#research-scientist-in-structural-biology Morphic Therapeutic is seeking a highly skilled and motivated Research Scientist trained in the field of structural biology, biophysics and protein biochemistry. Join

Re: [ccp4bb] Automatic restraints in Refmac too loose?

Can you attach a log file from earlier runs, and one more recent with the less satisfactory restraints Defaults are buried in the logs but often not easy to find.. Eleanor On 31 January 2018 at 10:40, Maria Håkansson wrote: > Hi Garib, > > Any news? > > Best

Re: [ccp4bb] Automatic restraints in Refmac too loose?

Hi Garib, Any news? Best regards, Maria Maria Håkansson, PhD, Crystallization Facility Manager Principal Scientist SARomics Biostructures AB Medicon Village SE-223 81 Lund, Sweden Mobile: +46 (0)76 8585706 Web: www.saromics.com > On 29 Jan 2018, at 19:06, Garib Murshudov

Re: [ccp4bb] Issues with latest XDS (20171218)

Dear all, a new BUILT of XDS is available for academic users at http://xds.mpimf-heidelberg.mpg.de . This reverts to the old distance refinement behavior with its larger radius of convergence, and is relevant for processing data from beamlines where the header distance is not accurate. Thanks