Re: [ccp4bb] open review?

2022-06-27 Thread Debanu Das
Hi James, I think it is quite different for publications/open publications (investigator initiated submissions on outcomes of grant-funded research, which are meant for public dissemination, even though all patentable IP is still employed-owned, whether a university, a national lab or a company)

Re: [ccp4bb] open review?

2022-06-27 Thread James Holton
Hey Debanu, Hmm. Last time I did it I didn't have to go through any IP lawyers to upload a pre-print to biorxiv.  What I was thinking of is something similar to that.  Researchers, on their own, deciding to upload their applications and reviews.  What would be the motivation? Well, I imagine

Re: [ccp4bb] arginine sidechain planarity issues

2022-06-27 Thread James Holton
It's the library: https://doi.org/10.1107/S2059798320013534 And it is not something that is terribly easy to fix. Arginine just has internal clashes so that plane is only flat sometimes. This is a lot of what led to the "Conformation Dependent Library", which I don't think is set up under

Re: [ccp4bb] open review?

2022-06-27 Thread John R Helliwell
Dear Debanu The UNESCO initiative as I mentioned is very interesting. I will offer alerts at key moments. At International Data Week in S Korea just concluded the Plenary session was on Open Science around the World. Africa, Latin America, S Korea and Malaysia talks all were defining open

Re: [ccp4bb] open review?

2022-06-27 Thread Debanu Das
Thinking about it some more, I think all the materials (patentable IP or trade secrets, which in the US are IP and under Defense of Trade Secrets Act) of a researcher are owned by the university. So just getting across tech transfer/IP of individual univs would be a massive hurdle before thinking

[ccp4bb] Postdoctoral Scientist for Protein Crystallography SRF at the CMD Oxford

2022-06-27 Thread Lizbé Koekemoer
Good evening We are seeking to appoint a Postdoctoral fellow for the Protein Crystallography Small Research Facility (PX-SRF), under the supervision of Professor Frank von Delft. The successful candidate will support all PX-SRF related activities, with the predominant focus on the projects in

Re: [ccp4bb] open review?

2022-06-27 Thread Debanu Das
Dear John, For sure it is an aspiration as a society and as a civilization: to think beyond individual nations. And for that we have some examples as you mentioned at the scientific (IUCr, PDB) and political level (UN). We also have the EU, ASEAN, NATO, etc. However, despite having these

Re: [ccp4bb] open review?

2022-06-27 Thread John R Helliwell
Dear Debanu, There is indeed much at stake here. Would I do it now, share my proposals, No. Would I do it if funders’ rules required it. Yes. When might funders’ rules require it eg when Tax payers insist that the priority is achieving societal goals asap. Might that happen in the foreseeable

Re: [ccp4bb] open review?

2022-06-27 Thread Debanu Das
>So, 2nd question is: would you do it? Would you upload your application >into the public domain for all to see? What about the reviewer comments? >If not, why not? Afraid people will steal your ideas? Well, once >something is public, its pretty clear who got the idea first. I do not think this

Re: [ccp4bb] open review?

2022-06-27 Thread John R Helliwell
Dear James, This is coming closer to your concept:- https://www.cos.io/initiatives/registered-reports?_ga=2.256611083.1499354793.1646731928-1289064925.1646731928 which I learned about in the current issue of Research Professional:-

[ccp4bb] arginine sidechain planarity issues

2022-06-27 Thread SUBSCRIBE CCP4BB rkrishnan
I am refining a structure at 2.2A resolution. I find that all my arginines show distortion after refinement with refmac5 even though they fit into the density really well. This is latest version of ccp4 8.00 running on windows 10. Is my library messed up in refmac5? Any other ideas?

[ccp4bb] Protein Crystallographer position at Sosei Heptares

2022-06-27 Thread Mathieu Rappas
We are currently seeking a Protein Crystallographer to join the crystallography team. You will be responsible for the structure determination of membrane proteins to support Sosei Heptares’ drug discovery efforts. This is an exceptional opportunity to participate in pioneering science with an