[ccp4bb] identifying hinges in flexible proteins

2011-08-26 Thread Stephen Cusack
We have structures of two states of a large multi-domain protein in which domain movements of up to 30 degrees are observed. Is there a programme available which attempts to determine rigid-body units and hinge regions in an 'unbiased' way? thanks for your suggestions, Stephen Cusack --

Re: [ccp4bb] identifying hinges in flexible proteins

2011-08-26 Thread Matthew BOWLER
Dear Stephen, I find DynDom very good (http://fizz.cmp.uea.ac.uk/dyndom/) otherwise the morph server (http://molmovdb.mbb.yale.edu/molmovdb/morph/) also performs similar analysis, cheers, Matt. On 26/08/2011 11:25, Stephen Cusack wrote: We have structures of two states of a large

Re: [ccp4bb] identifying hinges in flexible proteins

2011-08-26 Thread Martyn Winn
DynDom version 1.5 is part of the CCP4 suite. There is an interface for it under Program List. Although Steve Hayward appears to have a new version DynDom3D which we don't have. No idea if it would be better for your case. HTH Martyn On Fri, 2011-08-26 at 11:28 +0200, Matthew BOWLER wrote: