The Fitzpatrick lab, a member of the Zuckerman Mind Brain Behavior Institute at
Columbia University, has 5 openings for postdoctoral research associates funded
by a recent NIH U01 award to study the structural biology of tau and TDP-43 in
neurodegenerative diseases.
Situated in the heart of
Hi,
I am looking for alternative suppliers or similar items for the following
products that were carried by Hampton Research but have since been
discontinued.
1. Cryo vial holder. This is a hexagonal, metal holder that can hold 8
cryo vials. It is handy for freezing multiple crystals at once
Hi all,
Firstly, I’d like to say I’m really impressed with the volume, speed and detail
of the response that I have received. Thanks everyone.
Overloads
Eddie, Marc, Eleanor, Harry and Misha; thanks to all for suggesting collection
strategies and identifying the likely issue. Yesterday, I had
Dear Guto,
integration programs often ignore overloads, and most of them know the
detector cut-offs. mosflm has the option to estimate the resolution of
overloaded reflections from the none-overloaded parts. This should not
be a replacement for proper collection of a low resolution data set, but
Dear all,
Not directly a ccp4 question.
I am working on a multi-domain protein with multiple catalytic
centres. Purifying in gel-filtration (Äkta) with different buffers
gives a clear distinct peak indicating pure protein. We could even
crystallise it and determine 3D structure to about 2.5 A.
Dear all
Thanks for all the input both on- and off- the list. We shall definitely
look into these suggestions further and report again here in due course.
Kind regards
Sam
On Tue, 9 Oct 2018 at 19:12, Sam Tang wrote:
> Dear all
>
> Hello. We recently shot a crystal (a protein with small
Dear Markus,
I believe the strong assumption in the community is that a clear single peak of
appropriate Mw is a clear indication of pure protein, worthy intensive
crystallization efforts. Whether it is active is another question and this
should be measured.
For your analysis, it is not
