[ccp4bb] Post-doc Position in time-resolved BioSAXS at the Max IV Laboratory

Hi On behalf of my colleague Tómas Plivilic I would like to draw attention to a postdoctoral position within time_resolved BioSAXS opening at MAX IV in Lund, Sweden.. The CoSAXS beamline is a state-of-the-art multipurpose Small Angle X-ray Scattering (SAXS) instrument at MAX IV which is

Re: [ccp4bb] Help needed to make a clue about ligand

Looks like it could be a G-C dinucleotide? Tristan Croll Research Fellow Cambridge Institute for Medical Research University of Cambridge CB2 0XY > On 10 Jan 2018, at 04:09, Shankar Prasad Kanaujia > wrote: > > Dear All, > > Wishing you all a very happy and

[ccp4bb] PhD Positions, NIMHANS, Bangalore, India

PhD Positions at NIMHANS, Bangalore, India PhD positions are available in our Structural Biology lab. Our research work focus on drug discovery & development and understanding the molecular mechanisms of the protein targets associate with neurodegenerative diseases including Parkinson’s

[ccp4bb] reindexing mtz

Dear all, Looking to get some advice on reindexing an old dataset. I recently solved a structure of reasonable resolution at ~3A in C2. I had an old dataset at 4A in P213 that I never got a MR solution with until I solved the structure of it at 3A. I've recently gone back to to this and

[ccp4bb] postdoctoral position - National Institutes of Health, Bethesda

Please see below an opportunity for a postdoctoral fellowship in my lab at the NIH. We are looking for enthusiastic, talented scientists who will share our passion for microtubules and the beautiful world of tubulin diversity. Antonina *Postdoctoral Fellowship * *Cell Biology and Biophysics

[ccp4bb] post-doc position at SLAC/Stanford University

Post-doctoral position in the Biosciences Division at SLAC National Accelerator Laboratory/Stanford University The Biosciences Division at SLAC National Accelerator Laboratory/Stanford University has an opening for a post-doctoral position. Our group works at the interface of computation and

[ccp4bb] CCP4MG error after installation

Hello all, After installing ccp4 7.0 and all updates via the package manager on CentOS 6, I receive the following error messages upon running ccp4mg: libpng error: IDAT: invalid distance too far back QPainter::begin: Paint device returned engine == 0, type: 2 QPainter::end: Painter not

Re: [ccp4bb] Super protein wire model bender

I think those used to be sold by the Charles Supper Co. Check out their cat# 7145 http://www.charles-supper.com/en/page/product.cfm?idProduct=33 On 01/09/18 03:34, syed ibrahim wrote: Dear Friends I am looking for the provider details of instrument - Byron Bender (or super protein wire

[ccp4bb] Phenix version 1.13 released

The Phenix developers are pleased to announce that version 1.13 of Phenix is now available (build 1.13-2998). Binary installers for Linux, Mac OSX, and Windows platforms are available at the download site: http://phenix-online.org/download/ Highlights for this version: -

Re: [ccp4bb] Na-Binding Protein?

The human branched-chain alpha-ketoacid dehydrogenase requires a K+ ion to stabilize the binding of the cofactor thiamine diphosphate and to achieve maximum catalytic efficiency. See https://www.ncbi.nlm.nih.gov/pubmed/10745006 Diana ** Diana R.

Re: [ccp4bb] Na-Binding Protein?

That's very interesting. I guess it's an unusual manifestation of the Hofmeister series. It might give guidance to developers of screens for both crystallization and cryoEM. Thx, Patrick On 9 January 2018 at 15:44, Andrew Mesecar wrote: > Dear Jacob, > > > > One of my

Re: [ccp4bb] Na-Binding Protein?

Dear Jacob, The protease thrombin is another example. Thrombin is activated by Na+ (but not Li+ or K+). We have shown using NMR that Na+ binding allosterically stabilizes active conformations of thrombin. Additionally, numerous crystal structures of Na+-free (“slow” thrombin) and Na+-bound

Re: [ccp4bb] Na-Binding Protein?

Dear Jacob, One of my favorite examples of monovalent cation discrimination is by the enzyme Pyruvate Kinase. It prefers K(+), NH4(+), Rb(+) and Tl+ for maximum catalysis and then activity falls off as the monovalent cation sizes get larger, Cs(+) or smaller Na(+) >> Li (+). The conformations

Re: [ccp4bb] Na-Binding Protein?

Hi Jacob, Ion-channel and receptor folks have been working on these types of questions... see: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2629458/ if you are looking for a model system, perhaps engineer a version of calmodulin that is specific for Na+ rather than Ca++?  Perhaps someone

[ccp4bb] Na-Binding Protein?

Dear Crystallographers, Is anyone aware of a soluble protein which changes large-scale conformation +/- Na+, and is specific for Na+ per se, or at least ignores K+ and Ca++? E.g., Rb+ or Li+ might be okay. Structural info would be a plus, but not a sine qua non. Similarly, what about with K+

[ccp4bb] proxy settings for ccp4 package manager

Dear CCP4bb, does anyone know how I can make the ccp4 package manager use a proxy for downloading in Linux 64bit versions? This would make installing and updating a whole lot easier for me... I exported http_proxy, https_proxy, ftp_proxy (and all their capital letter equivalents) and setup the

Re: [ccp4bb] Super protein wire model bender

You could possibly look up Byron Rubin directly, he will likely have some ideas He was in upstate NY last that I heard: https://rbj.net/2015/08/28/molecular-art/ Good luck! -Conn Conn Mallett, PhD Carlsbad, CA conn.mallettgmail.com skype: conn.mallett On 9Jan2018 02:57, mesters wrote:

[ccp4bb] Any issues using CCP4 under Mac OSX and High Sierra

Are you Mac Users running CCP4 prods under High Sierra? Sorry if I've missed this in an archive search but as a serial late adopter of new OS releases, I've resisted upgrading until I know things work. BW Jon -- Professor Jon R Sayers, FRSB Department of Infection, Immunity & Cardiovascular

[ccp4bb] Diamond MX User Meeting at the CCP4 Study Weekend

Dear All, you can find the latest version of the Diamond MX User Meeting programme here: https://eventbooking.stfc.ac.uk/meeting-info?meetingID=147 The meeting will be held Wednesday 10th January 2018 in the main lecture theatre at the EMCC. Please note the earlier start time of 14:30h. We

Re: [ccp4bb] Super protein wire model bender

Supper Protein Wire Model Bender Cat.#7145 Not sure if they still make them. - J. - Am 09.01.18 um 09:34 schrieb syed ibrahim: Dear Friends I am looking for the provider details of instrument - Byron Bender (or super

[ccp4bb] study weekend live stream

Dear All a little clunky, but here are the instructions. Streaming starts for the what's new at 9am GMT tomorrow Go to http://www.stfc.ac.uk/about-us/our-purpose-and-priorities/freedom-of-information/webinars/ And the select your device type. Charles

[ccp4bb] Super protein wire model bender

Dear Friends I am looking for the provider details of instrument - Byron Bender (or super protein wire model bender), which is used to build protein wire model using Torsion angle for teaching purpose. I could not find any such provider. I greatly appreciate your help Thank you Dr. B. Syed