Re: [ccp4bb] dewar horror stories

2020-06-26 Thread Minmin 
A collaborated group met the similar situation with FedEx before and they 
switched to World courier afterwards. 
When your shipping dewar is no longer leaking of course, maybe you would like 
to check out the following link below. According to our users, crystals stored 
in the CombiPuck seem to get less or no ice up after shipment, possibly because 
the vials inside the puck helped keep the LN2 temp well.  The 16pins puck base 
format of the CombiPuck is the same format as the UniPuck. It is easy to switch 
from crystals stored in canes or any other formats of the pucks to the 
CombiPuck. It is also easy to retrieve the crystals from the CombiPuck back to 
the canes or any other pucks when needed.
https://www.mitegen.com/product/combipuck-system/


 
 
  On Thu, 25 Jun 2020 at 7:34, Jan Dohnalek wrote:   We 
have the suspicion (after several heavy FEDEX failures) they just toss them 
around ... then the neck easily breaks off.
That only explains everything we have seen with completely damaged samples, 
lost, flying around the dewar etc ...
When trying to communicate seriously with FEDEX about these issues - they even 
did not reply ...
Jan


On Wed, Jun 24, 2020 at 9:27 PM Patrick Loll  wrote:

Hello community,
We recently had a dry shipping dewar fail catastrophically (while en route to 
the beam line, so, major trauma). I sent it to a company that specializes in 
repair and refurbishing of cryogenic tanks, and they told me it has an internal 
leak, and hence is not reparable. I was expecting that the valve had failed, so 
the internal leak diagnosis came as a surprise.
Has anyone else had a similar experience? Any ideas about how an internal leak 
might come about? The dewar is (was) a Taylor/Wharton CX100, and it was 
traveling in its bespoke shipping case.
Thanks for any insights that might satisfy my curiosity and/or prevent future 
mishaps of this sort.
Cheers,
Pat
__
Patrick J.  Loll, PhDProfessor of Biochemistry & Molecular BiologyDrexel 
University College of MedicineRoom 10-102 New College Building245 N. 15th 
St.Philadelphia, PA 19102-1192 USA
(215) 762-7706pj...@drexel.edu


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-- 
Jan Dohnalek, Ph.D
Institute of Biotechnology
Academy of Sciences of the Czech Republic
Biocev
Prumyslova 595
252 50 Vestec near Prague
Czech Republic

Tel. +420 325 873 758


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[ccp4bb] PLEASE POST: Postdoctoral Position at Harvard Medical School

2020-06-26 Thread Chou, James 
Dear Sir/Madam:

Can you please post the following Postdoc Job Ad to ccp4bb?  Thank you!


A postdoctoral position is available immediately in the laboratory of James 
Chou at Harvard University Medical School.
The research project investigates an emerging concept in receptor biology that 
the transmembrane anchors of many immune receptors play a much more active role 
in receptor clustering and activation then previously appreciated.  The goal is 
to use NMR to reveal the membrane-interacting regions of single-pass 
transmembrane receptors at atomic resolution, and in combination with other 
biochemical and cell biological assays, to gain deeper understanding of 
receptor preligand autoinhibition and ligand-induced activation for many of the 
immune receptors currently being targeted for cancer immunotherapy and 
autoimmune treatment. For general information of our lab, please visit 
https://chou.hms.harvard.edu/.
The applicant must have a PhD and solid training in protein biochemistry, 
structural biology, or cell biology. Interested applicants should directly 
contact James Chou at 
james_c...@hms.harvard.edu.



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[ccp4bb] Pointless with fast close?

2020-06-26 Thread Aaron Finke 
I’m running Pointless on a large number of datasets, just to search for higher 
symmetry (the only options I’m inputting are xdsin XDS_ASCII.HKL and SETTING 
SYMMETRY-BASED). I’ve noticed that after the symmetry search, it pauses for a 
few seconds after the “Filename:” output, then ends normally with the pointless 
references. I don’t know why it’s doing that and it’s making a batch run of 
pointless much longer than it should be.

Any suggestions?

Thanks,
Aaron


--
Aaron Finke
Staff Scientist, MacCHESS
Cornell University
e-mail: af...@cornell.edu




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[ccp4bb] PhD studentship Institut de Biologie Structurale, Grenoble, France.

2020-06-26 Thread Franck Borel 
Dear all,
As part of the European ITN MepAnthi project, a PhD student position is 
available in the Synchrotron Group at the “Institut de Biologie Structurale”, 
Grenoble, France.
The project focuses on the development of selective and potent inhibitors of 
the anti-infective targets from MEP pathway (biosynthesis of the isoprenoid 
precursors), which is entirely absent in humans but is essential for medically 
relevant pathogens. The IBS’s task will be the structural analysis of the last 
two enzymes of the pathway (IspG and IspH), using a drug design approach.
Other phD positions are also available from other consortium partners. For 
further information and for application see: 
http://mepanti.hips-wordpress.helmholtz-hzi.de/ 

Regards

Franck BOREL



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