[ccp4bb] postdoc position

2021-09-28 Thread Smita

Oklahoma State University-Main Campus: College of Arts & Sciences: Department 
of Chemistry


The Department of Chemistry at Oklahoma State University invites applications 
for a Postdoctoral Fellow in Protein NMR in Mohanty lab.  The PI desires an 
applicant that can lead an independent project focusing on protein 
structure-function studies using high-resolution solution NMR, would be able to 
conduct molecular biology (sub-cloning and mutagenesis) work along with 
over-expression and purification of recombinant proteins, will provide updates 
on research progress during weekly group meetings, write scientific manuscripts 
for peer reviewed journals, disseminate research at national conferences 
(oral/poster presentations) and assist the PI with various research related 
work.

Minimum qualifications are a PhD in chemistry or biochemistry or biophysics 
along with familiarity with very good knowledge of protein NMR and 3D structure 
calculation, and other biophysical and computational techniques.  A record of 
scientific output (peer-reviewed publications) and strong writing and 
communications skills are also required.

For full consideration, please apply at https://apply.interfolio.com/93521 and 
submit curriculum vitae and contact information by October 15, 2021. 
Applications will continue to be accepted until the position has been filled.

Oklahoma State University, as an equal opportunity employer, complies with all 
applicable federal and state laws regarding non-discrimination and affirmative 
action.  Oklahoma State University is committed to a policy of equal 
opportunity for all individuals and does not discriminate based on race, 
religion, age, sex, color, national origin, marital status, sexual orientation, 
gender identity/expression, disability, or veteran status with regard to 
employment, educational programs and activities, and/or admissions.  For more 
information, visit https:///eeo.okstate.edu.




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[ccp4bb] CBMS WORKBENCH - SAXS and MX - October 11 - 13, 2021

2021-09-28 Thread Stojanoff, Vivian
Dear All,

You are cordially invited to participate in the Center for Biomolecular 
Structure workbenches on solution scattering and macromolecular 
crystallography. Registration is open for the October 11 through 13, 2021 
session and is free.

https://www.bnl.gov/cbmsworkbench/

Choose between workbenches or select both and learn of alternative structure 
determination methods. Participants will have the opportunity to send samples 
to measure during the workbench. Data analysis will be shared. If you are 
planning to send samples, make sure to register early to obtain the necessary 
credentials for remote access to the beam lines.


Invited Speakers:

- Elspeth Garman (University of Oxford)
- Al Kikhney (Xenocs Nordic ApS.)
- Kay Diederichs (Universitaet Konstanz)
- Dorothee  Liebschner (Berkeley Lab)
- Vukica Srajer (University of Chicago
- Maria Bewley (Penn State)
- Kevin Battaile (NY Structural Biology Center)
- Sean McSweeney (Center for Biomolecular Structure, BNL)

To register follow the link:

https://www.bnl.gov/cbmsworkbench/

Registration is a two-step process if you are not a BNL guest. If you have a 
BNL guest appointment you need only to register for the workbenches.

Kind regards

Vivian

--
Vivian Stojanoff, PhD
Education, Training, Outreach
User Program
p 1(631) 344 8375
e nsls.lifescien...@gmail.com
w https://www.bnl.gov/ps/lifesciences/

Address:
Center for Biomolecular Structure
National Synchrotron Light Source II
Building 745
Brookhaven National Laboratory
Upton NY 11973




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[ccp4bb] PhD position, University Bayreuth

2021-09-28 Thread Michael Weyand

Ph.D. student position in protein biochemistry and crystallography

We are looking for a highly motivated Ph.D. student for our protein 
biochemistry and crystallography laboratory at the Dept. of Biochemistry 
at University Bayreuth, Germany. We use protein crystallography and a 
variety of biochemical and biophysical methods for the structural and 
mechanistic characterization of cellular signalling systems with 
relevance to aging mechanisms and aging-related diseases. We then aim to 
develop small molecule modulators that exploit the identified signalling 
mechanisms. The PhD project will target soluble adenylyl cyclase, for 
exemplary publications see Proc Natl Acad Sci USA 111:3727-32; Nat Chem 
Biol. 12:838-44; ACS Med Chem Lett. 12:1283-1287


Our laboratory is located in a new building at the University of 
Bayreuth, Germany and equipped with state-of-the-art facilities for 
protein biochemistry, x-ray crystallography, and mass spectrometry. We 
offer excellent research opportunities and a stimulating environment for 
research in structural biology. The position is open immediately, salary 
base is TV-L E13/2.
The ideal candidate is a highly motivated student with strong interest 
in structural biology and prior experience in protein biochemistry. 
Additional experience in molecular biology and/or protein 
crystallization would be an asset.
Applications from handicapped persons will be favored when all other 
qualifications are equal. The University of Bayreuth is an equal 
opportunity employer and we therefore especially encourage women to apply.


Applications (including CV, research experience, and two names and 
contact information for references) should be sent as a PDF or by mail to

email:  sekretariat.bioche...@uni-bayreuth.de

Mail:
Prof. Dr. Clemens Steegborn
University of Bayreuth
Dept. Biochemistry, NW III
Universitaetsstrasse 30
95447 Bayreuth, Germany



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Re: [ccp4bb] post-doc position at KU Leuven, ligand-gated ion channels

2021-09-28 Thread Chris Ulens
A post-doctoral position is available at the Laboratory of Prof. Chris Ulens, 
KU Leuven, Belgium (http://www.xtal.be ). The research in 
the Laboratory of Structural Neurobiology is aimed at understanding the 
molecular mechanism of ligand-gated ion channels. Our methods rely on X-ray 
crystallography and cryo-EM in combination with electrophysiological recordings 
and fluorescence-based techniques. Our laboratory hosts an integrated 
macromolecular crystallization facility with a Mosquito crystallization robot 
and two RockImagers. We have access to a 200 kV Glacios microscope on campus as 
well as 300 kV JEOL CryoARM300 at the nearby EM facility in Brussels. Current 
projects are situated at the crossroads of structural elucidation and drug 
discovery of different pentameric ligand-gated ion channels.

We would like to recruit a post-doc with prior experience in cryo-EM or X-ray 
crystallography of membrane proteins. The position is open immediately and 
applications will be accepted until the position is filled. Applicants are 
requested to submit a CV with publication list and two references. E-mail to 
chris.ul...@kuleuven.be 


Selection of recent publications:


A lipid site shapes the agonist response of a pentameric ligand-gated ion 
channel. Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch 
J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan 
G, Nury H, Steyaert J, Baenziger JE, Ulens C. Nat Chem Biol. 
2019;15(12):1156-1164. doi: 10.1038/s41589-019-0369-4.


Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 
receptor via a common vestibule site. Brams M, Govaerts C, Kambara K, Price KL, 
Spurny R, Gharpure A, Pardon E, Evans GL, Bertrand D, Lummis SC, Hibbs RE, 
Steyaert J, Ulens C. Elife. 2020;9:e51511. doi: 10.7554/eLife.51511.


The structural basis for an on-off switch controlling Gβγ-mediated inhibition 
of TRPM3 channels. Behrendt M, Gruss F, Enzeroth R, Dembla S, Zhao S, Crassous 
PA, Mohr F, Nys M, Louros N, Gallardo R, Zorzini V, Wagner D, Economou A, 
Rousseau F, Schymkowitz J, Philipp SE, Rohacs T, Ulens C, Oberwinkler J. Proc 
Natl Acad Sci U S A. 2020;117(46):29090-29100. doi: 10.1073/pnas.2001177117.


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