[ccp4bb] postdoctoral position in structural biology of the tubulin code
A postdoctoral fellowship opportunity is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on the tubulin code using in vitro reconstitution and superresolution microscopy to capture the dynamic behavior of cytoskeletal complexes coupled with cryo-EM, single particle, and tomography to obtain structural information in vitro and in cells. For more information please visit: https://research.ninds.nih.gov/roll-mecak-lab*. * We are looking for Ph.D. graduates with a strong record of accomplishments and expertise in biochemistry and cell biology. Expertise with cryo-EM is not needed. We are happy to teach! The NIH has an outstanding cell and structural biology community, and the lab has regular access to state-of-the-art resources such as a Chameleon, Krios with K3 camera, Glacios, TIRF and lattice sheet microscopes, as well as cryo-FIB SEM. Please send your CV, a one-page research experience summary and contact information of three references to anton...@nih.gov Please write “Tubulin code fellowship” in the subject header. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] postdoctoral position at the NIH on structural cell biology of the cytoskeleton
A postdoctoral fellowship opportunity is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on the tubulin code using in vitro reconstitution and TIRF microscopy to capture the dynamic behavior of cytoskeletal complexes coupled with cryo-EM, single particle, and tomography to obtain structural information. For more information please visit: https://research.ninds.nih.gov/roll-mecak-lab*. *We are looking for Ph.D. graduates with a strong record of accomplishments and expertise in biochemistry and cell biology. Expertise with cryo-EM preferred, but not needed. We are happy to teach you! Incoming fellows are also encouraged to bring their own ideas that they could develop into research programs to help them launch independent PI positions. The NIH is committed to the continued education and career development of trainees through numerous courses and workshops offered on campus. The NIH has an outstanding cell and structural biology community, and the lab has regular access to state-of-the-art resources such as a Chameleon, Krios with K3 camera, Glacios, TIRF and lattice sheet microscopes as well as cryo-FIB SEM. The position is fully funded for up to five years. Please send your CV, a one-page research experience summary and contact information of three references to anton...@nih.gov Please write “Tubulin code cryo-EM” in the subject header. To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] postdoctoral positions at the NIH in cryo-EM, in vitro reconstitution and single molecule fluorescence microscopy
I am advertising for two postdoctoral positions in my lab. Our overall goal is to understand the structure and function of tubulin modification enzymes and microtubule effectors using a combination of cryo-EM, in vitro reconstitution and protein engineering. One postdoc position will be ideal for someone with good training in biochemistry and X-ray crystallography who would like to learn EM. The other is for someone with EM experience who wants to learn biochemistry, eukaryotic expression systems and light-microscopy based in vitro reconstitution assays. The NIH has a terrific structural and cell biology community. For information about the lab and the NIH, please go to: https://dir.ninds.nih.gov/ninds/RM_Lab/index.html https://irp.nih.gov/research-training and for a complete list of publications from the lab, go to: https://www.ncbi.nlm.nih.gov/myncbi/antonina.roll-mecak.1/bibliography/public/ Please email your CV and one page research summary to anton...@mail.nih.gov Antonina To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
[ccp4bb] postdoctoral position in microtubule structural biology at the NIH
Dear colleagues, There is an opening in my lab to study the structure and mechanism of microtubule regulators with an emphasis on the tubulin code. The formal announcement is pasted below. Thanks, Antonina *Cell Biology and Biophysics Unit, National Institutes of Health, Bethesda, USA* A postdoctoral fellowship opportunity is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on structural and functional studies of tubulin modification enzymes and molecular motors using a combination of X-ray crystallography, cryo-EM and single molecule fluorescence microscopy. Research in the Roll-Mecak lab focuses on deciphering the tubulin code ie how tubulin posttranslational modifications tune microtubule functions (see for instance Garnham et al., *Cell* 2015, Valenstein et al., *Cell* 2016, Vemu et al., *JBC* 2016; Zehr et al *Nature Struct & Molec Biology, *2017). We use a combination of biochemistry, X-ray crystallography, electron microscopy and single-molecule fluorescence techniques. For more information about the lab please visit: https://neuroscience.nih.gov/ninds/rm_lab/ I am looking for enthusiastic, self-motivated Ph.D. graduates with a strong publication record and expertise in molecular biology, biochemistry, X-ray crystallography or electron microscopy who welcome working in an interdisciplinary group with a supportive atmosphere and excellent resources. The Washington DC area is a great place to live with great access to cultural and outdoor activities. Experience with assembly of large protein complexes or structure determination by crystallographic methods or EM is a definite plus. The successful applicant will be awarded a NINDS Intramural Fellowship. Please send a CV, a one-page research experience summary and contact information of three references to anton...@mail.nih.gov Please write “Fellow - tubulin code” in the subject header. -- Antonina Roll-Mecak Senior Investigator and Chief Cell Biology and Biophysics Unit Porter Neuroscience Research Center NINDS and NHLBI National Institutes of Health Administrative contact: Karen Kendrick; Ph: 301-451-9223; Email: karen.kendr...@nih.gov <katie.tip...@nih.gov> Lab website: https://neuroscience.nih.gov/ninds/RM_Lab/
[ccp4bb] postdoctoral position - National Institutes of Health, Bethesda
Please see below an opportunity for a postdoctoral fellowship in my lab at the NIH. We are looking for enthusiastic, talented scientists who will share our passion for microtubules and the beautiful world of tubulin diversity. Antonina *Postdoctoral Fellowship * *Cell Biology and Biophysics Unit, National Institutes of Health, Bethesda, USA* A postdoctoral fellowship opportunity is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on structural and functional studies of tubulin modification enzymes and molecular motors using a combination of X-ray crystallography, cryo-EM and single molecule fluorescence microscopy. Research in the Roll-Mecak lab focuses on deciphering the tubulin code ie how tubulin posttranslational modifications tune microtubule functions (see for instance Garnham et al., *Cell* 2015, Valenstein et al., *Cell* 2016, Vemu et al., *JBC* 2016; Zehr et al *Nature Struct & Molec Biology *2017). For more information about the lab please visit: https://neuroscience.nih.gov/ninds/rm_lab/ I am looking for enthusiastic, self-motivated Ph.D. graduates with a strong publication record and expertise in molecular biology, biochemistry, X-ray crystallography or electron microscopy who will welcome working in an interdisciplinary group with a supportive atmosphere and excellent resources. The Washingon DC area is a great place to live with great access to cultural and outdoor activities. Experience with assembly of protein complexes or structure determination by crystallographic methods or EM is a must. The successful applicant will be awarded a NINDS Intramural Fellowship. Please send a CV, a one-page research experience summary and contact information of three references to anton...@mail.nih.gov Please write “Fellow - tubulin code” in the subject header. -- Antonina Roll-Mecak Senior Investigator and Chief Cell Biology and Biophysics Unit Porter Neuroscience Research Center NINDS and NHLBI National Institutes of Health Administrative contact: Karen Kendrick; Ph: 301-451-9223 <(301)%20451-9223>; Email: karen.kendr...@nih.gov <katie.tip...@nih.gov> Lab website: https://neuroscience.nih.gov/ninds/RM_Lab/
[ccp4bb] project scientist position in structural biology at the NIH in Bethesda, Maryland
DESCRIPTION The Roll-Mecak lab at the National Institutes of Health in Bethesda, Maryland is seeking to hire an expert researcher in the area of structural biology with emphasis on X-ray crystallography or electron microscopy of large multi-subunit complexes. Candidates should have expertise in solving de novo structures using X-ray crystallography or cryo-EM and extensive experience with eukaryotic expression systems, construct design and protein purification demonstrated through publications. Duties of the Position: • Express and purify various microtubule associated proteins to homogeneity • Characterize them biochemically and solve their structures. • Provide training to graduate students and postdoctoral fellows in structural biology techniques. • Prepare results for publication, presentations, and grant proposals. Basic Qualifications: • A Ph.D. or equivalent degree in structural biology, biophysics, biochemistry, or a related field is required at the time of application. Additional qualifications required by start date: • Post-Ph.D. experience in biochemical reconstitutions and solving structures of challenging targets using either X-ray crystallography or cryo-EM . • Excellent written and oral communication skills. Salary: The position provides excellent salary and benefits. Salary will be commensurate with experience and accomplishments. The initial appointment will be for one year with the possibility of renewal for a long-term position. To apply please submit your cover letter, curriculum vitae, and contact information for three references to anton...@mail.nih.gov
[ccp4bb] Postdoctoral Fellowship at the NIH – Structural Biology of Microtubule Modification Enzymes
Dear All, I am looking for a talented scientist to join my lab as a postdoctoral fellow to work on the structure and mechanism of tubulin modification enzymes (please see details below). Many thanks, Antonina *Postdoctoral Fellowship at the NIH – Structural Biology * A postdoctoral fellow position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on structural studies of tubulin modification enzymes. Research in the Roll-Mecak lab focuses on understanding how tubulin posttranslational modification enzymes generate the chemical complexity of cellular microtubules and how these modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., *NSMB* 2011, Szyk et al., *Cell* 2014; Garnham et al., *Cell* 2015; Yu et al., *JBC *2015). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques and a member of this lab will have an opportunity to use these different approaches to answer fundamental problems in microtubule biology. For more information about the lab and living in the Washington D.C. area, please visit: http://dir1.ninds.nih.gov/ninds/RM_Lab/ Self-motivated Ph.D. graduates with a strong publication record and expertise in molecular biology, biochemistry, X-ray crystallography or electron microscopy will be considered. Please send a CV, a one-page research experience summary and contact information of three references to anton...@mail.nih.gov Please write “Fellow- structural biology” in the subject header.
[ccp4bb] technician position at the NIH
Dear Structural Biology community, I would be grateful if you could please bring the following technician position to the attention of potential candidates. Many thanks, Antonina Roll-Mecak The Cell Biology and Biophysics Unit at the National Institutes of Health headed by Dr. Roll-Mecak has an open position for a research technician well-versed in molecular biology, biochemistry and large scale protein expression. Experience with large-scale expression in insect and mammalian cells is a definite advantage. The successful candidate can have a B.S., M.S. or Ph.D. and salary will be commensurate with experience and accomplishments. Research in the Roll-Mecak lab focuses on understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins. The research facilities in the lab are outstanding and the lab has state-of-the-art equipment. More information about the lab can be found at http://dir1.ninds.nih.gov/ninds/rm_lab/ Please send a CV and a brief summary of research experience to anton...@mail.nih.govanton...@mail.nih.gov.
[ccp4bb] postdoctoral fellowship position at the NIH
Dear Structural Biology community, I would be grateful if you could please bring the following postdoctoral position to the attention of talented graduate students. Many thanks, Antonina Roll-Mecak *Postdoctoral Fellowship at the NIH * *Cell Biology and Biophysics Unit, National Institutes of Health* A postdoctoral fellow position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on structural studies of tubulin modification enzymes. Research in the Roll-Mecak lab focuses on understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011, Garnham and Roll-Mecak, 2012, Szyk et al., 2014). The research facilities in the lab are outstanding and the lab has state-of-the-art equipment such as liquid handling systems, crystallization robots, regular access to the synchrotron, TIRF and confocal microscopes. For more information about the lab and living in the Washington D.C. area, please visit: http://dir1.ninds.nih.gov/ninds/RM_Lab/ The successful candidate must have a Ph.D. in a relevant discipline with a strong publication record and expertise in molecular biology, biochemistry and crystallography. Please send a CV, a one-page research experience summary and contact information of three references to anton...@mail.nih.gov Please write “Fellow- structural biology” in the subject header.
[ccp4bb] postdoctoral position - structural biology of microtubule regulators
*Postdoctoral Fellow – structural biology * *Cell Biology and Biophysics Unit, National Institutes of Health* A postdoctoral fellow position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak to work on structural studies of microtubule regulators. Research in the Roll-Mecak lab focuses on understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Garnham and Roll-Mecak, 2012; Szyk et al., 2011). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques and a member of this lab will have an opportunity to be exposed to all these areas. The research facilities in the lab are outstanding and the lab has state-of-the-art equipment such as crystallization robots, TIRF microscopes and regular access to the synchrotron. For more information about the lab and living in the Washington D.C. area, please visit: http://intra.ninds.nih.gov/rm_lab/ The successful candidate must have a Ph.D. in a relevant discipline with a strong publication record and expertise in molecular biology, biochemistry and crystallography. The position offers a generous salary and benefits package. Please send a CV, a one-page research experience summary and contact information of three references to anton...@mail.nih.gov Please write “Fellow- structural biology” in the subject header.
[ccp4bb] please see below advert for research technician position
The Cell Biology and Biophysics Unit at the National Institutes of Health headed by Dr. Roll-Mecak has an open position for a research technician well-versed in molecular biology and biochemistry and with solid experience in crystallization and structural biology. Experience with large-scale expression and purification of proteins from eukaryotic cells is a must. The successful candidate can have a B.S., M.S. or Ph.D. and salary will be commensurate with experience and accomplishments. More information about the lab can be found at http://intra.ninds.nih.gov/rm_lab/ Please send a CV and a brief summary of research experience to anton...@mail.nih.gov. Antonina Roll-Mecak
[ccp4bb] postdoctoral position at the NIH on microtubule regulators
A postdoctoral position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institutes of Health. The Roll-Mecak Laboratory is interested in understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011. Nature Struct. Molec. Biol. 8(11): 1250-8; Kormendi et al., 2012. J. Biol. Chem. 287(50):41569-75; Roll-Mecak, A. and Vale, R.D. 2008. Nature, 451(7176):363-7). We use a combination of biochemistry, structural biology, cell biology and high-resolution fluorescence techniques. Thus, a postdoctoral fellow in the lab would have the opportunity to move between these techniques and build upon an already strong background in structural biology and biochemistry. The Roll-Mecak lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda. The research facilities available are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF and confocal microscopes. For more information, please visit: http://intra.ninds.nih.gov/rm_lab/ The position will be fully funded by the NIH and is available immediately. We are looking for candidates who wish to work at the intersection between structural biology, enzymology and cell biology to explore the mechanism of tubulin modifying enzymes and have a strong background in molecular biology, protein biochemistry and structural biology. Other details: candidates should preferably have less than 2 years of postdoctoral experience. Please send a CV, a one-page research experience summary, and contact information of three references to anton...@mail.nih.gov Please write “Postdoctoral application” in the subject header. Antonina Roll-Mecak, Ph.D. Investigator and Chief Cell Biology and Biophysics Unit Porter Neuroscience Research Center NINDS and NHLBI/NIH Office Manager: Ms. Jessica Triplett Ph: 301-496-4305 Lab website:http://intra.ninds.nih.gov/rm_lab/
[ccp4bb] postdoctoral position in structural biology of microtubule regulators
A Postdoctoral position is available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institute of Neurological Disorders and Stroke to study the structure and mechanism of tubulin post-translational modification enzymes. The Roll-Mecak Laboratory is interested in understanding the interplay between microtubules and their regulators and how tubulin post- translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011. Nature Struct. Molec. Biol. 8(11): 1250-8; Roll-Mecak, A. and Vale, R.D. 2008. Nature, 451(7176):363-7; Roll-Mecak, A. and McNally, F.J. 2010. Curr. Opin. Cell Biol., 22(1):96-103). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques. We value a vibrant and collaborative environment where lab members share ideas, reagents and expertise and want to work on fundamental problems in cytoskeletal biology. The Roll-Mecak lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda. The NIH has a long tradition of research excellence in cytoskeletal biology and offers a stimulating environment for postdoctoral fellows interested in interdisciplinary training in structural biology and biophysics. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF and confocal microscopes. For more information, please visit: http://intra.ninds.nih.gov/rm_lab/ The position will be fully funded by the NIH, and is available immediately. We are looking for candidates who wish to work on structure-function studies of microtubule regulators and have a strong background in at least two of these areas: protein biochemistry, structural biology or cell biology. Other details: candidates should preferably have less than 2 years of postdoctoral experience. Please send a CV, a one-page research experience summary, and contact information of three references to anton...@mail.nih.gov Please write “Postdoctoral application” in the subject header.
[ccp4bb] postdoctoral position at the NIH focused on understanding the mechanism of cytoskeletal regulators
Postdoctoral positions are available in the Cell Biology and Biophysics Unit headed by Dr. Antonina Roll-Mecak at the National Institute of Neurological Disorders and Stroke. The Roll-Mecak Laboratory is interested in understanding the interplay between microtubules and their regulators and how tubulin post-translational modifications tune the behavior of motors and microtubule associated proteins (see for instance Szyk et al., 2011. Nature Struct. Molec. Biol. 8(11): 1250-8; Roll-Mecak, A. and Vale, R.D. 2008. Nature, 451(7176):363-7; Roll-Mecak, A. and McNally, F.J. 2010. Curr. Opin. Cell Biol., 22(1):96-103). We use a combination of biochemistry, structural biology, cell biology and single-molecule fluorescence techniques. Thus, a postdoctoral fellow in the lab would have the opportunity to move between these techniques and build upon an already strong background in one of these areas. We value a vibrant and collaborative environment where lab members share ideas, reagents and expertise and want to work on fundamental problems in cytoskeletal biology. The Roll-Mecak lab is located in the Porter Center for Neuroscience on the NIH main campus in Bethesda. The NIH has a long tradition of research excellence in cytoskeletal biology and offers a stimulating environment for postdoctoral fellows interested in interdisciplinary training in cell biology and biophysics. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as crystallization robots, liquid handling systems, TIRF and confocal microscopes. For more information, please visit: http://intra.ninds.nih.gov/rm_lab/ The position will be fully funded by the NIH, and is available immediately. We are looking for candidates who wish to work on mechanistic problems related to the microtubule cytoskeleton and have a strong background in at least two of these areas: molecular biology, protein biochemistry, structural biology, cell biology, microscopy or single molecule motor biophysics. Other details: candidates should preferably have less than 2 years of postdoctoral experience. Please send a CV, a one-page research experience summary, and contact information of three references to anton...@mail.nih.gov Please write “Postdoctoral application” in the subject header.
