[ccp4bb] BCA Winter Meeting 2013 (second flyer with correct deadline).
BCA Winter Meeting 2013 Title: New X-ray Developments and Macromolecular Structures in the Bragg Centenary Year. Venue: King's College London (New Hunt's House, Guy's Campus, London Bridge, SE1 1UL). Date: 16th December 2013. Organisers: The Randall Division of Cell Molecular Biophysics, KCL. - - - - - - - Invited speakers include: Bonnie Wallace, Birkbeck College London. Voltage-gated Sodium Channels: Complementary Insights into Structure and Function and Disease using Crystallography and Spectroscopy David Stuart, University of Oxford. In silico drug design - perhaps it really works James Naismith, St. Andrew's University. The UK plans for XFEL: what it can do for crystallography Ivan Laponogov, King's College London. Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport David Leys, University of Manchester. Structural studies on poly-ADP-ribose glycohydrolases Stefano Pernigo, King's College London. Structural basis of kinesin-1:cargo interaction Liz Carpenter, SGC Oxford. A novel structure for a nuclear membrane zinc metalloprotease involved in premature ageing diseases - - - - - - - - For details and registration, please visit the meeting website: http://crystallography.org.uk/bsg-winter-meeting-2013/ Registration deadline: Wednesday 11 December 2013. - - - - - - - - Contacts: Dr Mark Sanderson (mark.sander...@kcl.ac.uk) and Dr Yu Wai Chen (yu-wai.c...@kcl.ac.uk)
[ccp4bb] Approaching deadline for the CCP4 study weekend 2014 on Complementary Techniques
A reminder about the CCP4 Study weekend 4-5 January 2014 on Complementary Techniques. Please note: Deadline for early bird registration is 24th November. After this date the registration fee increases and there will be no student bursaries available. Up-to-date details of the meeting programme can be found at this link: http://www.cse.scitech.ac.uk/events/CCP4_2014/programme.html For registration, please follow the link: https://eventbooking.stfc.ac.uk/login?EVENT=147 What techniques can be combined with crystallographic analysis? Of all deposited structures in the PDB, more than half are oligomeric, and three quarters have a ligand bound. In-solution methods like SAXS or biophysical techniques allow us to validate the information on the molecular assembly. Biophysical techniques are also essential to probe ligands and co-factors. We address how to make ligand complexes with novel methods to mount and manipulate crystals. A session on drug design gives the perspective and discusses additional techniques such as NMR. Simulations and NMR also address the dynamic nature of macromolecules. EM techniques can be used to address macromolecular complexes of changing composition and go full circle with the X-ray analysis. You will learn how complementary methods help in structure determination and analysis, leading to a better understanding of the bio-macromolecules we study. The organisers. Ivo Tews, University of Southampton Jon Cooper, UCL.
[ccp4bb] CCP4 Study weekend 2014
CCP4 Study weekend 2014 on Complementary Techniques - programme now live at: http://www.cse.scitech.ac.uk/events/CCP4_2014/programme.html What techniques can be combined with crystallographic analysis? Of all deposited structures in the PDB, more than half are oligomeric, and three quarters have a ligand bound. In-solution methods like SAXS or biophysical techniques allow us to validate the information on the molecular assembly. Biophysical techniques are also essential to probe ligands and co-factors. We address how to make ligand complexes with novel methods to mount and manipulate crystals. A session on drug design gives the perspective and discusses additional techniques such as NMR. Simulations and NMR also address the dynamic nature of macromolecules. EM techniques can be used to address macromolecular complexes of changing composition and go full circle with the X-ray analysis. You will learn how complementary methods help in structure determination and analysis, leading to a better understanding of the bio-macromolecules we study. Interested? Then click here to registerhttps://eventbooking.stfc.ac.uk/login?EVENT=147. The organisers. Ivo Tews, University of Southampton Jon Cooper, UCL.
[ccp4bb] CCP4 Study Weekend 2014
CCP4 STUDY WEEKEND 2014 The next CCP4 study weekend will be held on 4th and 5th January 2014 at the University of Nottingham. The meeting is entitled Two Way Street - Complementary Methods and the aim is to explore methods that can be used to complement X-ray structure analysis and to learn how complementary techniques can be helpful in structure determination. Topics covered include: biophysics, SAXS, developments in sample manipulation, electron microscopy, protein dynamics and drug design. So far, invited speakers and chairs include: Dave Brown (Kent), Florent Cipriani (EMBL), Judit Debrenzski (Astra Zeneca), Frank von Delft (DLS), Frank Gabel (IBS), Sarah Harris (Leeds), Mike Hough (Essex), Adrian Mulholland (Bristol), Elena Orlova (Birkbeck), Arwen Pearson (Leeds), Javier Perez (Soleil), Antoine Royant (ESRF), Helen Saibil (Birkbeck), Eddie Snell (HW-MRI, USA), Alex Soares (BNL, USA), Glyn Williams (Astex), Huaying Zhao (NIH, USA). More information on the meeting programme and registration can be found at the following link: http://www.cse.scitech.ac.uk/events/CCP4_2014/ Please note that the closing date for registration is Friday 13th December 2013. The organisers. Ivo Tews (University of Southampton) Jon Cooper (UCL)
[ccp4bb] 'Crystals, X-rays and Proteins' back in print...
For info, Dennis Sherwood's book 'Crystals, X-rays and Proteins' is now firmly back in print (well, as Sherwood and Cooper, this time)... and it has quite a few citations of Acta Cryst papers, with titles ;-) A couple of tiny errata can be found at the following link... http://www.ucl.ac.uk/~rmhajc0/ Please keep me posted if any more 'typos' should show up! Thank you. Jon Cooper Laboratory for Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Department of Medicine (Royal Free Campus), Rowland Hill Street, London, NW3 2PF.
[ccp4bb] BCA Winter Meeting - reminder
The BCA Biological Structures Group winter meeting will be held on Friday 18th December 2009 at the Royal Free Hospital in north London, starting at 11.00 am. The theme of the meeting is 'Pathological Proteins' - the aim is to encompass structural studies of proteins involved in a range of disease processes including neurological disorders, amyloid disease, infection and immunity. Registration closes on 4th December. Confirmed speakers -- Prof. Salam Al-Karadaghi, Department of Molecular Biophysics, University of Lund, Sweden. ‘Insights into the molecular mechanism of Friedreich's ataxia from X-ray crystallography and electron microscopy studies of frataxin.’ Dr Kate Brown, Department of Life Sciences, Imperial College London. 'Scraping the surface of C. difficile: structural characterisation of SLPs and toxin B.' Dr Carien Dekker, The Institute of Cancer Reseach, London. 'The crystal structure of the eukaryotic chaperonin CCT.' Dr Leo James, MRC Laboratory of Molecular Biology, Cambridge. 'Cyclophilin A: HIV co-factor or antiviral?' Dr Simon Kolstoe, UCL Department of Medicine (Royal Free Campus). ‘Targeting transthyretin - X-ray crystallography and rational drug design.’ Dr Paul McEwan, Centre for Biomolecular Science, University of Nottingham. 'Loosening the grip on von Willebrand factor by breaking the thumb of GPib.' Dr Arefeh Seyedarabi, School of Biological and Chemical Sciences, Queen Mary, University of London. 'Structural and functional studies of IpaH9.8 from Shigella flexneri'. Dr Ian Taylor, National Institute of Medical Research, Mill Hill, London. ‘The retroviral capsid and restriction factors.’ Prof Gabriel Waksman, ISMB, Birkbeck / UCL. ‘Structural Biology of Type IV Secretion Systems.’ -- The Royal Free Hospital is about 15 - 30 minutes on the Underground from most London main line rail terminals. Registration and further details about the meeting are now available at the following link: http://www.bsg.crystallography.org.uk/wint09.html http://www.bsg.crystallography.org.uk/wint09.html I look forward to seeing you there. Jon Cooper -- Laboratory for Protein Crystallography, Centre for Amyloidosis and Acute Phase Proteins, UCL Department of Medicine (Royal Free Campus), Rowland Hill Street, London, NW3 2PF. E-mail: j.b.coo...@medsch.ucl.ac.uk
