helpful.
If you are interested in this position, please email your CV and contact info
of two or more referees to zh...@chop.swmed.edu.
Happy New Year and all the Best!
Hong Zhang, Ph.D.
Associate Professor
Department of Biophysics and Department of Biochemistry
UT Southwestern
ession systems, cell culture, various
biochemical and biophysical techniques to study protein-protein interactions
are also highly desirable.
To apply, please email CV and contact info of two or more referees to
zh...@chop.swmed.edu.
All the Best,
Hong Zhang, Ph.D.
Associate Pro
These are excellent questions. There are probably no easy answers.
The situation with flexible loops is that the peptide chain adapts multiple
(>=3) conformations here and we traditional crystallographers are trying to
fit one model into the density that is the result of multiple confirmations.
Th
Even today, we still try to soak existing native protein crystals with heavy
atoms at the same time while SeMet substituted protein is prepared.
Nearly half of the times, we are able to solve the structure with HA (always
SIRAS) before we have the SeMet protein.
A recent example:
Structure. 200
Is the water molecule in question coordinated to any other group(s)?
-Original Message-
From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Kevin
Jin
Sent: Tuesday, February 07, 2012 10:22 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] On pKa of Aspartic acid
As we
Xe is also an excellent anomalous scatterer at Cu Ka wavelength. It is
particularly good for SIRAS phasing since Xe derivative is usually highly
isomorphous to the native crystals.
Hong
_
Hong Zhang, Ph.D.
Department of Biochemistry
University of Texas Southwestern Medical
