Hi Richard and All,
At Formulatrix we haven't yet seen an algorithm that can come even close to
what the human brain can do for drop scoring. Crystals come in too many shapes,
sizes, plates, and confusing backgrounds making automated detection
extraordinarily difficult. Because of this, we
board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Ellen
Gualtieri
Sent: Thursday, February 20, 2014 5:14 PM
To: CCP4BB@JISCMAIL.AC.UK
Subject: Re: [ccp4bb] identifying protein crystals via visible light only?
Hi Richard and All,
At Formulatrix we haven't yet seen an algorithm that can come even
Hi Richard,
Do you require visible light only?
In any case, i remember a neat paper describing using Hoffman modulation, as
well as polarisation and phase contrast. Pure analog computing ;) What stroke
me then (and now) is that the standard microscopy kit people use does not use
the
Some years ago, I remember hearing about a microscope that used *visible* light
combined with some proprietary image processing algorithm to
distinguish between protein crystals, salt, and background. I can't remember
the company name or researchers involved.
Has anyone here heard of this?
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Jürgen
..
Jürgen Bosch
Johns Hopkins University
Bloomberg School of Public Health
Department of Biochemistry Molecular Biology
Johns Hopkins Malaria Research Institute
615 North Wolfe Street,
, February 04, 2014 10:10 AM
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] identifying protein crystals via visible light only?
Some years ago, I remember hearing about a microscope that used *visible*
light combined with some proprietary image processing algorithm to
distinguish between protein