Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Ian Tickle
On 21 June 2013 19:45, Douglas Theobald dtheob...@brandeis.edu wrote: The current way of doing things is summarized by Ed's equation: Ispot-Iback=Iobs. Here Ispot is the # of counts in the spot (the area encompassing the predicted reflection), and Iback is # of counts in the background

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Douglas Theobald
Ian, I really do think we are almost saying the same thing. Let me try to clarify. You say that the Gaussian model is not the correct data model, and that the Poisson is correct. I more-or-less agree. If I were being pedantic (me?) I would say that the Poisson is *more* physically realistic

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Douglas Theobald
On Sat, Jun 22, 2013 at 1:04 PM, Douglas Theobald dtheob...@brandeis.eduwrote: Feel free to prove me wrong --- can you derive Ispot-Iback, as an estimate of Itrue, from anything besides a Gaussian? OK, I'll prove myself wrong. Ispot-Iback can be derived as an estimate of Itrue, even when

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Ian Tickle
On 22 June 2013 18:04, Douglas Theobald dtheob...@brandeis.edu wrote: Ian, I really do think we are almost saying the same thing. Let me try to clarify. I agree, but still only almost! --- but in truth the Poisson model does not account for other physical sources of error that arise

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Douglas Theobald
On Sat, Jun 22, 2013 at 1:56 PM, Ian Tickle ianj...@gmail.com wrote: On 22 June 2013 18:04, Douglas Theobald dtheob...@brandeis.edu wrote: --- but in truth the Poisson model does not account for other physical sources of error that arise from real crystals and real detectors, such as dark

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Frank von Delft
A fascinating discussion (I've learnt a lot!); a quick sanity check, though: In what scenarios would these improved estimates make a significant difference? Or rather: are there any existing programs (as opposed to vapourware) that would benefit significantly? Cheers phx On

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Douglas Theobald
On Jun 22, 2013, at 6:18 PM, Frank von Delft frank.vonde...@sgc.ox.ac.uk wrote: A fascinating discussion (I've learnt a lot!); a quick sanity check, though: In what scenarios would these improved estimates make a significant difference? Who knows? I always think that improved

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Nat Echols
On Sat, Jun 22, 2013 at 3:18 PM, Frank von Delft frank.vonde...@sgc.ox.ac.uk wrote: In what scenarios would these improved estimates make a significant difference? Perhaps datasets where a unusually large number of reflections are very weak, for instance where TNCS is present, or where the

Re: [ccp4bb] ctruncate bug?

2013-06-22 Thread Ronald E Stenkamp
I agree with Frank. This thread has been fascinating and educational. Thanks to all. Ron On Sat, 22 Jun 2013, Douglas Theobald wrote: On Jun 22, 2013, at 6:18 PM, Frank von Delft frank.vonde...@sgc.ox.ac.uk wrote: A fascinating discussion (I've learnt a lot!); a quick sanity check,