[Freesurfer] Qdec question when examining group differences with continuous covariate and nuisance factor

2018-03-22 Thread James Allebone
Hi there, I am running an analysis to examine differences in cortical thickness between two groups (clinical vs control) and have entered ICV as a nuisance variable and age as a covariate. The analysis results in qdec do not appear to give a result that answers the question: does the average

Re: [Freesurfer] qdec question

2017-12-31 Thread Douglas Greve
If you are asking whether you can mix versions of FS, the answer is no. You should analyze all your data using a single version. On 12/30/17 3:27 AM, Giovanni de Marco wrote: Hello, I’ve got a question concerning qdec running with freesurfer. I just downloaded the latest version of

[Freesurfer] qdec question

2017-12-30 Thread Giovanni de Marco
Hello, I’ve got a question concerning qdec running with freesurfer. I just downloaded the latest version of freesurfer. Before to run qdec, I read than I have to run "recon-all -s ID -all" (about 7 hours) and then recon-all -s ID -qcache (about 5'). So I tried it with one subject and everything

[Freesurfer] Qdec question

2017-11-01 Thread Mohamed Ali Bahri
Dear Freesurfer experts, I would like to use "Qdec" tool to study the between groups changes of volume/cortical thickness of one region (Perirhinal) belonging to the Brodmann areas. As I understand Qdec load only the aparc and aseg stat lists and not the BA stat list. I am wondering if we

Re: [Freesurfer] qdec question

2016-11-28 Thread Douglas N Greve
Try using the data in the csdbase.y.ocn.dat file rather than transferring the clusters back into the individual space. What are you using to do the ROI-based analysis? You have to make sure that the design matrix and contrasts are exactly the same. You can do this in matlab with FS commmands,

[Freesurfer] qdec question

2016-11-24 Thread Yaakub, Siti Nurbaya
Dear Experts, I'm looking at differences in area between two groups of subjects in FreeSurfer using qdec. I've delineated an ROI based on a cluster that showed significant differences in surface area between the two groups (taking gender into account, and with age and ICV as nuisance

[Freesurfer] Qdec question

2015-12-10 Thread sabin khadka
Hi all - When you get a significant cluster after doing monte-carlo simulation, we get peak vertex/Talairach coordinates and also saved in *summary files. Is there a way to find all the parcellated regions (Desikan, or, Destriuex) in the significant clusters?

Re: [Freesurfer] QDEC question

2015-07-26 Thread Dr Sampada Sinha
Hello Dr Greve, Many thanks for replying to me. We are not including eTIV as a covariate. Since we did not find any correlation with the thickness. Kind regards, Sampada ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu

Re: [Freesurfer] QDEC question

2015-07-24 Thread Dr Sampada Sinha
Dear freesurfer experts, I was able to figure out the problem! I was not supposed to write the eTIV values in my .dat.table which I did and for that reasons my continuous factors were being read as 4 instead of 3. Thanks and regards, Sampada AIIMS, Delhi

Re: [Freesurfer] QDEC question

2015-07-24 Thread Dr Sampada Sinha
Dear Freesurfer experts, Thanks for your valuable input. Since, comparison with global thickness does not provide any valuable information we have decided to forego the average thickness and lh-thickness comparison and now added eTIV as another covariate with age ​ and ​ lh/rh thickess ( ​please

Re: [Freesurfer] QDEC question

2015-07-24 Thread Douglas Greve
I don't know what is going on with that, but one thing you should do is to normalize the eTIV (ie, remove it's mean and divide by the std dev). Also, why are you including eTIV in the first place? Thickness does not change with head size, only volume and surface area. doug On 7/24/15 2:34

Re: [Freesurfer] QDEC question

2015-07-22 Thread Douglas Greve
The statements are automatically generated based on the names of the variables you provide. In this case, you've included (global?) lh thickness as a covariate. This will have a slope when plotted against thickness at a given vertex, and this slope my differ between genders. The average

Re: [Freesurfer] QDEC question

2015-07-20 Thread Douglas N Greve
Does /home/anup/Desktop/QDEC/fsaverage/surf/lh.white exist? If not, cd /home/anup/Desktop/QDEC/ ln -s $FREESURFER_HOME/subjects fsaverage It looks like you will have a second problem in that the subject class GenderFemale-DiagnosisSCA1 does not have any members doug On 07/17/2015 08:17 AM, Dr

[Freesurfer] QDEC question

2015-07-17 Thread Dr Sampada Sinha
Dear freesurfer experts, I am trying to do cortical thickness-age correlation in Spinocerebellar ataxia patients (SCA1 and SCA2). ## I successfully ran qcache command on these 10 subjects of SCA1 and SCA2. ##Since my discrete factors are *Gender *(Male and Female) and* Diagnosis* (SCA1 and SCA2),

Re: [Freesurfer] Qdec question

2014-09-08 Thread Douglas Greve
If you know the vertex you want to extract, then you can run something like mri_segstats --i y.mgh --crs vertexno 0 0 --avgwf out.dat where y.mgh is the stack created by qdec and out.dat is the data file you want doug On 8/28/14 8:37 AM, Abrishamchi, Aurash David wrote: Hello, I still

[Freesurfer] Qdec question

2014-08-28 Thread Abrishamchi, Aurash David
Hello, I still cannot solve this issue. All help will be appreciated. I am running Qdec analysis on about 100 subjects and correcting with FDR. Once I do this I click the find clusters and go to max button and Qdec gives me a plot of all the data as well as taking me to the max vertex in the

Re: [Freesurfer] qdec question

2014-05-06 Thread Anna Jonsson
thank you. I have another question; I am getting several significant clusters for group, when correcting for multiple comparisons and total brain size and age, but when I enter sex in, msot of these disappear, but i do not understand whether this is a power issue (as qdec automatically

Re: [Freesurfer] qdec question

2014-05-06 Thread Douglas Greve
If you don't see an effect of gender, then it is ok to leave it out of the model. I could be affecting the power as you suspect. doug On 5/6/14 3:55 AM, Anna Jonsson wrote: thank you. I have another question; I am getting several significant clusters for group, when correcting for multiple

[Freesurfer] qdec question

2014-05-05 Thread Anna Jonsson
Dear group, when using the qdec gui interface, I was wondering where the button or the likes is to change the estimation from its standard doss to dods (different osnet, different slope). I believe I can do this somewhere on the qdec gui without changing to mri_glmfit?

Re: [Freesurfer] qdec question

2014-05-05 Thread Douglas N Greve
DOSS is not working in QDEC. It should be disabled in 5.3 doug On 05/05/2014 09:39 AM, Anna Jonsson wrote: Dear group, when using the qdec gui interface, I was wondering where the button or the likes is to change the estimation from its standard doss to dods (different osnet, different

Re: [Freesurfer] Qdec question: opening previously ran group analysis

2014-01-28 Thread Douglas N Greve
You can do it in QDEC by going running QDEC, then loading the surface, curvature, and overlay files (they are in the output folder (default Untitled)). Load the sig.mgh file for the overlay. This can also be done in tksurfer. doug On 01/24/2014 11:11 AM, Estephan Moana wrote: Dear

[Freesurfer] qdec question: discrepancy in sig. clusters

2013-07-26 Thread Maria Kharitonova
Hello, I have another newbie question. I'm running qdec, trying to compare cortical thickness in children with and without ADHD. However, I'm seeing a discrepancy between the clusters that are significant according to the terminal (after applying the Monte-Carlo simulation with default

Re: [Freesurfer] qdec question: discrepancy in sig. clusters

2013-07-26 Thread Douglas Greve
Hi Maria, can you tar up the qdec output folder and send it to our file drop? I'm traveling now, so it might be the 1st week of august before I can take a look. You can also go into the qdec output folder and run tksurfer to show you the results. doug On 7/26/13 1:37 PM, Maria Kharitonova

Re: [Freesurfer] qdec question

2013-03-12 Thread Douglas Greve
I think the right way to do it is to use the symmetric template (fsaverage_sym) as the target (instead of fsaverage). You will need to run the symmetric registration. See http://surfer.nmr.mgh.harvard.edu/fswiki/Xhemi (if you have 5.2, you do not need to download anything). You can map

[Freesurfer] qdec question

2013-03-11 Thread Kristina Nalbandian
Hello! I am running qdec group analysis on my patient data and have one very important question. I am studying the differences between two Epilepsy subtypes. Each one of my patients has a hemisphere of onset, either Left or Right, that I would like to use in looking for differences between

[Freesurfer] qdec question

2013-03-11 Thread Kristina Nalbandian
Hello! I am running qdec group analysis on my patient data and have one very important question. I am studying the differences between two Epilepsy subtypes. Each one of my patients has a hemisphere of onset, either Left or Right, that I would like to use in looking for differences between

Re: [Freesurfer] qdec question

2013-01-04 Thread Nick Schmansky
Maria, In qdec there is not a built-in mechanism to restrict analysis to a particular region. By design it runs a whole-cortex analysis, masking just the medial (non-cortical) region, and then i suppose if your lucky (if your ROI is significant compared to everything else) your region will

Re: [Freesurfer] qdec question

2013-01-04 Thread Douglas N Greve
Hi Maria, you can do it with the commandline tools (mri_glmfit) by specifying --mask or --label. This is a common thing to do, but you will need to run simulations for multiple comparisons correction. doug On 01/04/2013 06:35 AM, Nick Schmansky wrote: Maria, In qdec there is not a

[Freesurfer] qdec question

2013-01-01 Thread Maria Jalbrzikowski
Dear Freesurfer users, I have a question regarding qdec and I would like your help. When conducting qdec analyses, is it possible to restrict the analyses to specific brain regions? I would like to limit my qdec analyses to brain regions typically associated with social cognition and have

[Freesurfer] QDEC question

2012-02-02 Thread Dalwani, Manish
Hi Freesurfer users, I ran a QDEC analysis and loaded annotation. Is there a way to click on the activated cluster and print the region with co-ordinates? Thanks, Manish Dalwani ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu

Re: [Freesurfer] QDEC question

2012-02-02 Thread Dalwani, Manish
Ok I figured that it is ctrl and mouse click on the co-ordinate of interest. How can I get the cluster size out? Thanks, Manish On 2/2/12 2:47 PM, Manish Dalwani manish.dalw...@ucdenver.edu wrote: Hi Freesurfer users, I ran a QDEC analysis and loaded annotation. Is there a way to click on

Re: [Freesurfer] QDEC question

2012-02-02 Thread Dalwani, Manish
Nevermind, I figured out both my questions! I just have to read the instructions carefully :) Manish On 2/2/12 3:02 PM, Manish Dalwani manish.dalw...@ucdenver.edu wrote: Ok I figured that it is ctrl and mouse click on the co-ordinate of interest. How can I get the cluster size out? Thanks,

[Freesurfer] QDEC question about covariates

2010-04-17 Thread Manabu Kubota
Dear FreeSurfer experts, Hello, I started to use FreeSurfer recently. I want to do group analysis with QDEC in order to compare 2 groups (control group and patient group), regressing out age and gender. When I include 2 discrete factors (diagnosis and gender) and 1 continuous factor (age), and

Re: [Freesurfer] qdec question

2009-07-24 Thread Nick Schmansky
@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] qdec question The newest version of FreeSurfer does not contain any changes to qdec I believe. Allison ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu

Re: [Freesurfer] qdec question

2009-07-23 Thread Douglas N Greve
...@nmr.mgh.harvard.edu] Sent: Friday, 10 July 2009 4:15 AM To: Prapti Gautam Cc: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] qdec question The newest version of FreeSurfer does not contain any changes to qdec I believe. Allison -- Douglas N. Greve, Ph.D. MGH-NMR Center gr

Re: [Freesurfer] qdec question

2009-07-22 Thread Prapti Gautam
for your help, Prapti -Original Message- From: Allison Stevens [mailto:astev...@nmr.mgh.harvard.edu] Sent: Friday, 10 July 2009 4:15 AM To: Prapti Gautam Cc: freesurfer@nmr.mgh.harvard.edu Subject: Re: [Freesurfer] qdec question The newest version of FreeSurfer does not contain any changes

Re: [Freesurfer] qdec question

2009-07-09 Thread Allison Stevens
The newest version of FreeSurfer does not contain any changes to qdec I believe. Allison -- On Thu, 9 Jul 2009, Prapti Gautam wrote: Dear Freesurfers, I just have some quick questions regarding qdec: 1. How many covariates does the latest version of qdec allow you to select? I

[Freesurfer] qdec question

2009-07-08 Thread Prapti Gautam
Dear Freesurfers, I just have some quick questions regarding qdec: 1. How many covariates does the latest version of qdec allow you to select? I am using FS version 4.3.0 and I cannot select more than 2 continuous variables. I am just wondering if a newer version allows you to

[Freesurfer] Qdec question

2009-02-16 Thread Devdutta W
Hi, I am using qdec for analysis and noticed that in addition to thickness measures I can select others such as area and volume. I have been trying to figure out what exactly the area measure refers to (surface area, etc.). I did not find it on the website. Can someone clarify that for me? If

[Freesurfer] Qdec question

2009-02-13 Thread Devdutta W
Hi, I have been running into an error while using Qdec. *Error in Analyze: Couldn't open file $SUBJECT_DIR/SUBJECT_FOLDER/surf/lh.thickness.fwhm10.fsaverage.mgh* I checked and the file is there in that folder. I know this file is created when recon-all is run with -qcache option. I have run

Re: [Freesurfer] Qdec question

2009-02-13 Thread Pratap Kunwar
hi Dev, You might have wrong SUBJECTS_DIR, check it using echo $SUBJECTS_DIR Hi, I have been running into an error while using Qdec. *Error in Analyze: Couldn't open file $SUBJECT_DIR/SUBJECT_FOLDER/surf/lh.thickness.fwhm10.fsaverage.mgh* I checked and the file is there in that folder. I

[Freesurfer] Qdec question

2007-11-05 Thread Xiangchuan Chen
Hi all, I am using Qdec to examine the anatomical differences between two groups of subjects. The surface-based measures I can select are thickness, area, area.pial, sulc, curv, and jacobian_white. Could anybody tell me what anatomical features the later three (sulc, curv, and jacobian_white)

Re: [Freesurfer] Qdec question

2007-11-05 Thread Bruce Fischl
sulc = average convexity from our 1999 reconII paper. Essentially measures the depth/height of each point above the average surface. curv = smoothed mean curvature. jacobian_white = the jacobian of the spherical transform. Measures the amount of distortion needed to warp a subject into

Re: [Freesurfer] Qdec question

2007-11-05 Thread Nick Schmansky
Xiangchuan Chen, You might want to look at the slides downloadable from the top of this page: http://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial which contain pictures showing the meaning of 'curv' and 'sulc'. Nick sulc = average convexity from our 1999 reconII paper. Essentially measures

[Freesurfer] QDEC question

2007-09-14 Thread Narly A Golestani
Dear all, I have 2 questions regarding doing analyses using QDEC: 1) can I use QDEC to analyse results on data for which I ran recon-all using the last (ie: older, not most recent) version of Freesurfer, or should I rerun recon-all on all the data using the new version of Freesurfer? (I hope

Re: [Freesurfer] QDEC question

2007-09-14 Thread Nick Schmansky
Narly, You can use qdec on data processed with the v3.0 processing stream, as long as you create the 'qcached' files that qdec needs, which is done using v4.0 recon-all, as you have done. You can ignore those warning message. They are informative (I will change it to say INFO). The ?h.volume