Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Hi Everyone, Back in May I was very excited to learn that there was some movement toward allowing Freesurfer to utilize the higher than 1mm iso. resolutions of some of our structural images, which could be fantastic help in subcortical segmentations. Is this something that is still in the works for the next release? gratefully, Joshua - Joshua Lee Graduate Student Center for Mind and Brain Department of Psychology University of California, Davis 530.747.3805 On Thu, May 31, 2012 at 5:49 PM, Bruce Fischl fis...@nmr.mgh.harvard.eduwrote: Hi Joshua sorry, I haven't found the time to really work on it. I spent a couple of hours and found some problems, but haven't found the time to fix them Bruce On Thu, 31 May 2012, Joshua Lee wrote: Hi Bruce, I'm just checking in to see how it turned out with the subcortical segmentation using the high resolution images I sent. Best, Joshua - Joshua Lee Graduate Student Center for Mind and Brain Department of Psychology University of California, Davis 530.747.3805 On Tue, May 15, 2012 at 5:29 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? áOr do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: á á áHi Joshua á á áyes, we already have upgraded mris_make_surfaces to take higher á á áres data á á áand refine the surfaces with it. Haven't tried it on the aseg á á áyet, but if á á áyou upload a sample dataset I could see how hard it is. á á ácheers á á áBruce á á áOn Mon, 14 May 2012, á á áJoshua Lee wrote: á á á Dear Freesurfers, á á á á á á Over the last years, MR imaging technology hasimproved such á á áthat sub 1-mm á á á isotropic scans can be obtained with good signal to noise á á ácharacteristics. á á á For example, our lab uses 0.7mm isotropic structural MR á á áimages. I understand á á á that the Freesurfer pipeline will up-sample these to 1mm á á áisotropic, but it á á á seems a shame that so much information is left unused which á á ácould be used to á á á improve the accuracy of sub-cortical and cortical á á ásegmentation. My question á á á is whether there are any plans at Freesurfer to change the á á áreference á á á standard resolution from 1mm isotropic, or provide another á á ásolution that can á á á help researchers make the most of your technology. á á á á á á Sincerely, á á á á á á á á á Joshua á á á - á á á Joshua á á á á á á á á á __**_ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.**edu/mailman/listinfo/** freesurfer https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/**compliancelinehttp://www.partners.org/complianceline. If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. __**_ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.**edu/mailman/listinfo/**freesurferhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Oops i just realized I only sent this to Bruce: Thanks! It looks like this involves some manual intervention. Matt., I assume you're not manually making control points on 1000s of subjects (I imagine this is for the human connectcome project). Is your code public somewhere? Cheers, Michael On Tue, May 15, 2012 at 7:36 PM, Michael Waskom mwas...@stanford.eduwrote: Thanks! It looks like this involves some manual intervention. Matt., I assume you're not manually making control points on 1000s of subjects (I imagine this is for the human connectcome project). Is your code public somewhere? Cheers, Michael On Tue, May 15, 2012 at 9:14 AM, Bruce Fischl fis...@nmr.mgh.harvard.eduwrote: sure, here's mine. Matt's is probably a lot more polished as they intend to run it on hundreds or thousands of subjects On Tue, 15 May 2012, Michael Waskom wrote: Hi Bruce, Sounds cool, I'd be very interested in checking out the script. Cheers, Michael On Tue, May 15, 2012 at 5:29 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua __**_ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.**edu/mailman/listinfo/** freesurferhttps://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/**compliancelinehttp://www.partners.org/complianceline. If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Only because I was lazy! You can use surfaces for normalization too. I think the script I gave Matt probably had that in it On May 16, 2012, at 9:21 PM, Michael Waskom mwas...@stanford.edu wrote: Oops i just realized I only sent this to Bruce: Thanks! It looks like this involves some manual intervention. Matt., I assume you're not manually making control points on 1000s of subjects (I imagine this is for the human connectcome project). Is your code public somewhere? Cheers, Michael On Tue, May 15, 2012 at 7:36 PM, Michael Waskom mwas...@stanford.edu wrote: Thanks! It looks like this involves some manual intervention. Matt., I assume you're not manually making control points on 1000s of subjects (I imagine this is for the human connectcome project). Is your code public somewhere? Cheers, Michael On Tue, May 15, 2012 at 9:14 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: sure, here's mine. Matt's is probably a lot more polished as they intend to run it on hundreds or thousands of subjects On Tue, 15 May 2012, Michael Waskom wrote: Hi Bruce, Sounds cool, I'd be very interested in checking out the script. Cheers, Michael On Tue, May 15, 2012 at 5:29 AM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Yes, I have a modified script working. For the white surface, the essentials are the same as Bruce's script but it has some additional stuff (e.g register T2w to T1w), and I call it in the middle of the recon-all rather than at the end. For the pial surface, I have done some more complicated stuff, which I'd love to talk to Bruce about some more some time. :) Peace, Matt. -Original Message- From: freesurfer-boun...@nmr.mgh.harvard.edu [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl Sent: Tuesday, May 15, 2012 7:29 AM To: Michael Waskom Cc: FreeSurfer Subject: Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Hi Bruce and Michael, That would be very nice. Do I just email you the hi-res *whole-brain*mprages, or is their another way to get the images to you? On the other hand, I'm a fair hand at scripting. I'd be willing to experiment with any scripts that you might provide. Last, and on an unrelated note. Is that programming position at Freesurfer still open? I know someone looking for an interesting and challenging position like that. Best, Joshua - Joshua Lee Graduate Student Center for Mind and Brain Department of Psychology University of California, Davis 530.747.3805 On Tue, May 15, 2012 at 6:00 AM, Matt Glasser m...@ma-tea.com wrote: Yes, I have a modified script working. For the white surface, the essentials are the same as Bruce's script but it has some additional stuff (e.g register T2w to T1w), and I call it in the middle of the recon-all rather than at the end. For the pial surface, I have done some more complicated stuff, which I'd love to talk to Bruce about some more some time. :) Peace, Matt. -Original Message- From: freesurfer-boun...@nmr.mgh.harvard.edu [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl Sent: Tuesday, May 15, 2012 7:29 AM To: Michael Waskom Cc: FreeSurfer Subject: Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future you need to call mris_make_surfaces directly. It's a bit complicated as you need to intensity normalize and register the hires volume to the surfaces first. I have an example script if anyone is interested, but no one has used it yet but me I don't think (unless Matt Glasser has gotten his version working, which on second thought he probably has) On Mon, 14 May 2012, Michael Waskom wrote: Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.edu wrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
[Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
I'd be interested to hear how this goes too. Thanks, Matt. -Original Message- From: freesurfer-boun...@nmr.mgh.harvard.edu [mailto:freesurfer-boun...@nmr.mgh.harvard.edu] On Behalf Of Bruce Fischl Sent: Monday, May 14, 2012 4:09 PM To: Joshua Lee Cc: FreeSurfer Subject: Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
Re: [Freesurfer] Freesurfer 1mm Isotropic standard and the Future
Hi Bruce, Is there a flag for this on recon-all? Or do you need to use mri_make_surfaces directly? Best, Michael On Mon, May 14, 2012 at 2:09 PM, Bruce Fischl fis...@nmr.mgh.harvard.eduwrote: Hi Joshua yes, we already have upgraded mris_make_surfaces to take higher res data and refine the surfaces with it. Haven't tried it on the aseg yet, but if you upload a sample dataset I could see how hard it is. cheers Bruce On Mon, 14 May 2012, Joshua Lee wrote: Dear Freesurfers, Over the last years, MR imaging technology hasimproved such that sub 1-mm isotropic scans can be obtained with good signal to noise characteristics. For example, our lab uses 0.7mm isotropic structural MR images. I understand that the Freesurfer pipeline will up-sample these to 1mm isotropic, but it seems a shame that so much information is left unused which could be used to improve the accuracy of sub-cortical and cortical segmentation. My question is whether there are any plans at Freesurfer to change the reference standard resolution from 1mm isotropic, or provide another solution that can help researchers make the most of your technology. Sincerely, Joshua - Joshua ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail. ___ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.