Re: [Freesurfer] Multiple comparison correction on subcortical volume

2017-01-10 Thread Douglas N Greve
I would say yes, but I've seen plenty of pubs that do not correct. The 
bonferroni correction is fine. You could also try FDR (though on 4 
points it might not make much sense).


On 01/10/2017 01:47 PM, neuroimage analyst wrote:
> Hi,
>
> I extracted thalamic, caudate, and putamen volume (left hemisphere), 
> and cingulate thickness (right hemisphere) from 
> freesurfer's parcellation. Then I compare these volumes and thickness 
> across two groups using R and found significant differences in these 
> measurements. Do I have to correct for multiple comparisons?
>
> If yes, how do I do that? Does this make sense to divide the p-value/4 
> and if the p-value < p-value/4 then the test is Bonferroni corrected? 
> If no, what do I say in my results that the test statistic is not 
> inflated?
>
> Thanks
>
> Regards
>
> --VM
>
>
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> Freesurfer mailing list
> Freesurfer@nmr.mgh.harvard.edu
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[Freesurfer] Multiple comparison correction on subcortical volume

2017-01-10 Thread neuroimage analyst
Hi,

I extracted thalamic, caudate, and putamen volume (left hemisphere), and
cingulate thickness (right hemisphere) from freesurfer's parcellation. Then
I compare these volumes and thickness across two groups using R and found
significant differences in these measurements. Do I have to correct for
multiple comparisons?

If yes, how do I do that? Does this make sense to divide the p-value/4 and
if the p-value < p-value/4 then the test is Bonferroni corrected? If no,
what do I say in my results that the test statistic is not inflated?

Thanks

Regards

--VM
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