Re: [HCP-Users] Demographic and behavioral subject data

[Harms, Michael]

All subject currently hosted in the WU-Minn HCP project on ConnectomDB were processed in a consistent manner using the "500 subject release" pipelines.  The release field refers to when they were originally released, and probably isn't of much use to you.
  (Where it is relevant, is that if someone downloaded data from say the Q2 release, or has a Connectome-in-a-Box from say the Q2 release, that particular data  used a somewhat different set of processing relative to the same subject's data as currently hosted
 on the database).


In terms of selecting subjects, you can filter on pretty much any variable in the database using the "Data Filters" on the Subject Dashboard.  Note that every individual in HCP can be considered young and healthy in a broad sense, so depending on how exactly
 you further filter, you might end up with a "super-heathy" sample, which might not be what you want.


cheers,
-MH




-- 
Michael Harms, Ph.D.

---
Conte Center for the Neuroscience of Mental Disorders
Washington University School of Medicine
Department of Psychiatry, Box 8134
660 South Euclid Ave. 
Tel: 314-747-6173
St. Louis, MO  63110 
Email: mha...@wustl.edu






From: Joelle Zimmermann 
Date: Monday, November 30, 2015 10:26 AM
To: "hcp-users@humanconnectome.org" 
Subject: [HCP-Users] Demographic and behavioral subject data





Hello everyone,

I want to pick a group of subjects from the 500 subjects +MEG2  for which I will perform (rsfMRI and dMRI) analysis. These should be young, healthy, subjects that have no abnormalities and cognitively able.


Does anyone have any pointers about how I can go weeding out subjects? Under "Subject Information" of all subjects, I can see a list of all subjects, where I can see age, release and gender. And when I click on the subject, I find a bunch of behavioral
 tests and their results for that subject.


Should subjects from different releases be combined? Which is the most recent release?


Are there certain scores for cognitive assessments that are considered to weed out the cognitively able, healthy subjects? Is this data available somewhere in a spreadsheet form, without having to go into each subject and scrolling though their various
 assessment scores?


Anything would help.
Thanks,
Joelle




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Re: [HCP-Users] Demographic and behavioral subject data

[Jennifer Elam]

Hi Joelle,

All the HCP subjects are considered healthy young adults with no diagnosed 
cognitive abnormalities. They do, of course, have a range of abilities and 
scores on the behavioral tests we conduct. 

 

There is a lot of information in Chapter 1 of the current 500 Subjects 
Reference Manual 

  for navigating the behavioral data and for filtering subjects—please check it 
out. There is also a  “Download CSV button” at the upper right of the subject 
Dashboard that will allow you to download all the open access behavioral data 
in one spreadsheet. Look at the sections of the Reference Manual on Restricted 
access data to see if you need to apply for access to that data for your 
purposes.

 

As detailed in the Introduction section of the Reference Manual, subjects that 
were originally acquired or released in different quarters/releases can be 
combined in analyses because we ran all subjects through the same analysis 
pipelines as of the 500 subjects release (as long as you are using data 
currently in ConnectomeDB, the S500 Connectome in a Box, or S500 S3 Bucket 
data).  Again, as stated in the Ref Manual Introduction, one thing you should 
be aware of is that the fMRI data collected in Q1 and part of Q2 was 
reconstructed with a slightly different reconstruction algorithm than 
subsequent data. You can filter on Study Completion>Image Reconstruction Info: 
3T MR>3T MR fMRI Recon Version, if you think it might make a difference to your 
analyses. 

 

In the upcoming 900 Subjects release (coming within the next couple of weeks!), 
the new subject data will also be comparable to the 500 Subject release data. 
Pipeline changes since the S500 release have been mostly minor and have only 
added to the data available (more details to come). 

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
  314-362-9387
  el...@pcg.wustl.edu
  www.humanconnectome.org

 

From: hcp-users-boun...@humanconnectome.org 
[mailto:hcp-users-boun...@humanconnectome.org] On Behalf Of Joelle Zimmermann
Sent: Monday, November 30, 2015 10:27 AM
To: hcp-users@humanconnectome.org
Subject: [HCP-Users] Demographic and behavioral subject data

 

Hello everyone,

 

I want to pick a group of subjects from the 500 subjects +MEG2  for which I 
will perform (rsfMRI and dMRI) analysis. These should be young, healthy, 
subjects that have no abnormalities and cognitively able.

 

Does anyone have any pointers about how I can go weeding out subjects? Under 
"Subject Information" of all subjects, I can see a list of all subjects, where 
I can see age, release and gender. And when I click on the subject, I find a 
bunch of behavioral tests and their results for that subject.

 

Should subjects from different releases be combined? Which is the most recent 
release?

 

Are there certain scores for cognitive assessments that are considered to weed 
out the cognitively able, healthy subjects? Is this data available somewhere in 
a spreadsheet form, without having to go into each subject and scrolling though 
their various assessment scores?

 

Anything would help.

Thanks,

Joelle

 

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Re: [HCP-Users] Demographic and behavioral subject data

[Joelle Zimmermann]

Hi Michael and Jennifer,

Thank you both for your help, much appreciated. One remaining question - is
there currently any cutoff for cognitive scores (i.e. for the MMSE for ex)
for subjects being included in the 500 release dataset?  Can't find mention
of it in the ref manual, so Im guessing probably not.

Thanks,
Joelle

On Mon, Nov 30, 2015 at 11:49 AM, Jennifer Elam  wrote:

> Hi Joelle,
>
> All the HCP subjects are considered healthy young adults with no diagnosed
> cognitive abnormalities. They do, of course, have a range of abilities and
> scores on the behavioral tests we conduct.
>
>
>
> There is a lot of information in Chapter 1 of the current 500 Subjects
> Reference Manual
> 
> for navigating the behavioral data and for filtering subjects—please check
> it out. There is also a  “Download CSV button” at the upper right of the
> subject Dashboard that will allow you to download all the open access
> behavioral data in one spreadsheet. Look at the sections of the Reference
> Manual on Restricted access data to see if you need to apply for access to
> that data for your purposes.
>
>
>
> As detailed in the Introduction section of the Reference Manual, subjects
> that were originally acquired or released in different quarters/releases
> can be combined in analyses because we ran all subjects through the same
> analysis pipelines as of the 500 subjects release (as long as you are using
> data currently in ConnectomeDB, the S500 Connectome in a Box, or S500 S3
> Bucket data).  Again, as stated in the Ref Manual Introduction, one thing
> you should be aware of is that the fMRI data collected in Q1 and part of Q2
> was reconstructed with a slightly different reconstruction algorithm than
> subsequent data. You can filter on Study Completion>Image Reconstruction
> Info: 3T MR>3T MR fMRI Recon Version, if you think it might make a
> difference to your analyses.
>
>
>
> In the upcoming 900 Subjects release (coming within the next couple of
> weeks!), the new subject data will also be comparable to the 500 Subject
> release data. Pipeline changes since the S500 release have been mostly
> minor and have only added to the data available (more details to come).
>
>
>
> Best,
>
> Jenn
>
>
>
> Jennifer Elam, Ph.D.
> Outreach Coordinator, Human Connectome Project
> Washington University School of Medicine
> Department of Anatomy and Neurobiology, Box 8108
> 660 South Euclid Avenue
> St. Louis, MO 63110
> 314-362-9387
> el...@pcg.wustl.edu
> www.humanconnectome.org
>
>
>
> *From:* hcp-users-boun...@humanconnectome.org [mailto:
> hcp-users-boun...@humanconnectome.org] *On Behalf Of *Joelle Zimmermann
> *Sent:* Monday, November 30, 2015 10:27 AM
> *To:* hcp-users@humanconnectome.org
> *Subject:* [HCP-Users] Demographic and behavioral subject data
>
>
>
> Hello everyone,
>
>
>
> I want to pick a group of subjects from the 500 subjects +MEG2  for which
> I will perform (rsfMRI and dMRI) analysis. These should be young, healthy,
> subjects that have no abnormalities and cognitively able.
>
>
>
> Does anyone have any pointers about how I can go weeding out subjects?
> Under "Subject Information" of all subjects, I can see a list of all
> subjects, where I can see age, release and gender. And when I click on the
> subject, I find a bunch of behavioral tests and their results for that
> subject.
>
>
>
> Should subjects from different releases be combined? Which is the most
> recent release?
>
>
>
> Are there certain scores for cognitive assessments that are considered to
> weed out the cognitively able, healthy subjects? Is this data available
> somewhere in a spreadsheet form, without having to go into each subject and
> scrolling though their various assessment scores?
>
>
>
> Anything would help.
>
> Thanks,
>
> Joelle
>
>
>
> ___
> HCP-Users mailing list
> HCP-Users@humanconnectome.org
> http://lists.humanconnectome.org/mailman/listinfo/hcp-users
>

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Re: [HCP-Users] Demographic and behavioral subject data

[Jennifer Elam]

Hi Joelle,

 

Here are the HCP Inclusion Criteria:

Inclusion Criteria:

No significant history of psychiatric disorder, substance abuse, neurological, 
or cardiovascular disease

-No person report of diagnosis by a treating physician

-No hospitalization

No pharmacologic or behavioral treatment (12 months duration or longer) by a 
specialty-trained physician (psychiatrist, neurologist, cardiologist) or 
therapist (e.g., psychologist, social worker)

-Childhood ADHD with no current treatment is allowed

-Transient childhood seizures allowed (clarify what type)

-Migraines allowed if not taking daily psychoactive medications

Age 22 to 35

Ability to give valid informed consent

MMSE score of 24 or above

 

Here are the HCP Exclusion Criteria:

Two or more non-provoked (e.g., not due to fever) seizures or a diagnosis of 
epilepsy

Any genetic disorder, such as Cystic Fibrosis 

Use of daily prescription medications for migraines in the past month

Multiple Sclerosis, Cerebral Palsy

Brain tumor or Stroke

Currently on chemotherapy or immunomodulatory agents, or history of radiation 
or chemotherapy that could affect the brain

Sickle Cell Disease

Thyroid Hormone Treatment in the past month

Treatment for Diabetes in the past month (do not exclude for gestational or 
diet controlled diabetes)

Head Injury If:

  LOC>30 minutes or Amnesia >24 hours

  Change in Mental Status >24 hours or CT findings consistent with TBI

  3 or more concussive (mild) TBIs

Premature Birth (Born >37 weeks for non-twins, born <34 weeks for twins. If 
weeks unknown, less than 5 lbs. at birth for non-twins.

Current Pregnancy

Unsafe metal or devices in the body (Cardiac Pacemaker, cochlear implant, 
aneurism clip)

Moderate to Severe Claustrophobia

 

Hope that helps.

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: Joelle Zimmermann [mailto:joelle.t.zimmerm...@gmail.com] 
Sent: Monday, November 30, 2015 11:12 AM
To: Jennifer Elam
Cc: hcp-users@humanconnectome.org
Subject: Re: [HCP-Users] Demographic and behavioral subject data

 

Hi Michael and Jennifer,

 

Thank you both for your help, much appreciated. One remaining question - is 
there currently any cutoff for cognitive scores (i.e. for the MMSE for ex) for 
subjects being included in the 500 release dataset?  Can't find mention of it 
in the ref manual, so Im guessing probably not.

 

Thanks,

Joelle

 

On Mon, Nov 30, 2015 at 11:49 AM, Jennifer Elam <el...@pcg.wustl.edu> wrote:

Hi Joelle,

All the HCP subjects are considered healthy young adults with no diagnosed 
cognitive abnormalities. They do, of course, have a range of abilities and 
scores on the behavioral tests we conduct. 

 

There is a lot of information in Chapter 1 of the current 500 Subjects 
Reference Manual 
<http://humanconnectome.org/documentation/S500/HCP_S500+MEG2_Release_Reference_Manual.pdf>
  for navigating the behavioral data and for filtering subjects—please check it 
out. There is also a  “Download CSV button” at the upper right of the subject 
Dashboard that will allow you to download all the open access behavioral data 
in one spreadsheet. Look at the sections of the Reference Manual on Restricted 
access data to see if you need to apply for access to that data for your 
purposes.

 

As detailed in the Introduction section of the Reference Manual, subjects that 
were originally acquired or released in different quarters/releases can be 
combined in analyses because we ran all subjects through the same analysis 
pipelines as of the 500 subjects release (as long as you are using data 
currently in ConnectomeDB, the S500 Connectome in a Box, or S500 S3 Bucket 
data).  Again, as stated in the Ref Manual Introduction, one thing you should 
be aware of is that the fMRI data collected in Q1 and part of Q2 was 
reconstructed with a slightly different reconstruction algorithm than 
subsequent data. You can filter on Study Completion>Image Reconstruction Info: 
3T MR>3T MR fMRI Recon Version, if you think it might make a difference to your 
analyses. 

 

In the upcoming 900 Subjects release (coming within the next couple of weeks!), 
the new subject data will also be comparable to the 500 Subject release data. 
Pipeline changes since the S500 release have been mostly minor and have only 
added to the data available (more details to come). 

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: hcp-users-boun...@human

Re: [HCP-Users] Demographic and behavioral subject data

[Jennifer Elam]

One correction to the following:

Again, as stated in the Ref Manual Introduction, one thing you should be aware 
of is that the fMRI data collected in Q1, Q2, and part of Q3 was reconstructed 
with a slightly different reconstruction algorithm than subsequent data. You 
can filter on Study Completion>Image Reconstruction Info: 3T MR>3T MR fMRI 
Recon Version, if you think it might make a difference to your analyses.

 

This is stated correctly in the 500 Subjects Reference Manual 
<http://humanconnectome.org/documentation/S500/HCP_S500+MEG2_Release_Reference_Manual.pdf>
  and on the HCP Issues Wiki 
<https://wiki.humanconnectome.org/pages/viewpage.action?pageId=29589520> , 
which has some more information on the ramifications of the reconstruction 
algorithm change. Please look at these documents before embarking on analyses 
involving HCP data so you can be aware of all the current information that 
might affect your results. 

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: hcp-users-boun...@humanconnectome.org 
[mailto:hcp-users-boun...@humanconnectome.org] On Behalf Of Jennifer Elam
Sent: Monday, November 30, 2015 10:49 AM
To: 'Joelle Zimmermann'; hcp-users@humanconnectome.org
Subject: Re: [HCP-Users] Demographic and behavioral subject data

 

Hi Joelle,

All the HCP subjects are considered healthy young adults with no diagnosed 
cognitive abnormalities. They do, of course, have a range of abilities and 
scores on the behavioral tests we conduct. 

 

There is a lot of information in Chapter 1 of the current 500 Subjects 
Reference Manual 
<http://humanconnectome.org/documentation/S500/HCP_S500+MEG2_Release_Reference_Manual.pdf>
  for navigating the behavioral data and for filtering subjects—please check it 
out. There is also a  “Download CSV button” at the upper right of the subject 
Dashboard that will allow you to download all the open access behavioral data 
in one spreadsheet. Look at the sections of the Reference Manual on Restricted 
access data to see if you need to apply for access to that data for your 
purposes.

 

As detailed in the Introduction section of the Reference Manual, subjects that 
were originally acquired or released in different quarters/releases can be 
combined in analyses because we ran all subjects through the same analysis 
pipelines as of the 500 subjects release (as long as you are using data 
currently in ConnectomeDB, the S500 Connectome in a Box, or S500 S3 Bucket 
data).  Again, as stated in the Ref Manual Introduction, one thing you should 
be aware of is that the fMRI data collected in Q1 and part of Q2 was 
reconstructed with a slightly different reconstruction algorithm than 
subsequent data. You can filter on Study Completion>Image Reconstruction Info: 
3T MR>3T MR fMRI Recon Version, if you think it might make a difference to your 
analyses. 

 

In the upcoming 900 Subjects release (coming within the next couple of weeks!), 
the new subject data will also be comparable to the 500 Subject release data. 
Pipeline changes since the S500 release have been mostly minor and have only 
added to the data available (more details to come). 

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: hcp-users-boun...@humanconnectome.org 
[mailto:hcp-users-boun...@humanconnectome.org] On Behalf Of Joelle Zimmermann
Sent: Monday, November 30, 2015 10:27 AM
To: hcp-users@humanconnectome.org
Subject: [HCP-Users] Demographic and behavioral subject data

 

Hello everyone,

 

I want to pick a group of subjects from the 500 subjects +MEG2  for which I 
will perform (rsfMRI and dMRI) analysis. These should be young, healthy, 
subjects that have no abnormalities and cognitively able.

 

Does anyone have any pointers about how I can go weeding out subjects? Under 
"Subject Information" of all subjects, I can see a list of all subjects, where 
I can see age, release and gender. And when I click on the subject, I find a 
bunch of behavioral tests and their results for that subject.

 

Should subjects from different releases be combined? Which is the most recent 
release?

 

Are there certain scores for cognitive assessments that are considered to weed 
out the cognitively able, healthy subjects? Is this data available somewhere in 
a spreadsheet form, without having to go into each subject and scrolling though 
their various assessment scores?

 

Anything would help.

Thanks,

Joelle

 

___
HCP-Users mailing

Re: [HCP-Users] Demographic and behavioral subject data

[Joelle Zimmermann]

Hi Jennifer,

Thanks a lot for your help, that's really useful.

With regard to the reconstruction - I just wanted to clarify, and apologies
if this is in the manual but I did not find it - When I filter by 'Study
Completion' > 'Image Reconstruction' > 3T MR fMRI recon, I have 2 options -
r177 and r227.

Which is the more recent/ considered 'better' reconstruction method?

I suspect that the r227 is better if I am interested in using both
diffusion MRI data and fMRI data, as the r227 is available for both,
whereas r177 is only available for fMRI data, and not for dMRI. Is that
correct?

Thanks,
Joelle

On Mon, Nov 30, 2015 at 1:48 PM, Jennifer Elam <el...@pcg.wustl.edu> wrote:

> Hi Joelle,
>
>
>
> Here are the *HCP Inclusion Criteria*:
>
> Inclusion Criteria:
>
> No significant history of psychiatric disorder, substance abuse,
> neurological, or cardiovascular disease
>
> -No person report of diagnosis by a treating physician
>
> -No hospitalization
>
> No pharmacologic or behavioral treatment (12 months duration or longer) by
> a specialty-trained physician (psychiatrist, neurologist, cardiologist) or
> therapist (e.g., psychologist, social worker)
>
> -Childhood ADHD with no current treatment is allowed
>
> -Transient childhood seizures allowed (clarify what type)
>
> -Migraines allowed if not taking daily psychoactive
> medications
>
> Age 22 to 35
>
> Ability to give valid informed consent
>
> MMSE score of 24 or above
>
>
>
> Here are the *HCP Exclusion Criteria*:
>
> Two or more non-provoked (e.g., not due to fever) seizures or a diagnosis
> of epilepsy
>
> Any genetic disorder, such as Cystic Fibrosis
>
> Use of daily prescription medications for migraines in the past month
>
> Multiple Sclerosis, Cerebral Palsy
>
> Brain tumor or Stroke
>
> Currently on chemotherapy or immunomodulatory agents, or history of
> radiation or chemotherapy that could affect the brain
>
> Sickle Cell Disease
>
> Thyroid Hormone Treatment in the past month
>
> Treatment for Diabetes in the past month (do not exclude for gestational
> or diet controlled diabetes)
>
> Head Injury If:
>
>   LOC>30 minutes or Amnesia >24 hours
>
>   Change in Mental Status >24 hours or CT findings consistent with TBI
>
>   3 or more concussive (mild) TBIs
>
> Premature Birth (Born >37 weeks for non-twins, born <34 weeks for twins.
> If weeks unknown, less than 5 lbs. at birth for non-twins.
>
> Current Pregnancy
>
> Unsafe metal or devices in the body (Cardiac Pacemaker, cochlear implant,
> aneurism clip)
>
> Moderate to Severe Claustrophobia
>
>
>
> Hope that helps.
>
>
>
> Best,
>
> Jenn
>
>
>
> Jennifer Elam, Ph.D.
> Outreach Coordinator, Human Connectome Project
> Washington University School of Medicine
> Department of Anatomy and Neurobiology, Box 8108
> 660 South Euclid Avenue
> St. Louis, MO 63110
> 314-362-9387
> el...@pcg.wustl.edu
> www.humanconnectome.org
>
>
>
> *From:* Joelle Zimmermann [mailto:joelle.t.zimmerm...@gmail.com]
> *Sent:* Monday, November 30, 2015 11:12 AM
> *To:* Jennifer Elam
> *Cc:* hcp-users@humanconnectome.org
> *Subject:* Re: [HCP-Users] Demographic and behavioral subject data
>
>
>
> Hi Michael and Jennifer,
>
>
>
> Thank you both for your help, much appreciated. One remaining question -
> is there currently any cutoff for cognitive scores (i.e. for the MMSE for
> ex) for subjects being included in the 500 release dataset?  Can't find
> mention of it in the ref manual, so Im guessing probably not.
>
>
>
> Thanks,
>
> Joelle
>
>
>
> On Mon, Nov 30, 2015 at 11:49 AM, Jennifer Elam <el...@pcg.wustl.edu>
> wrote:
>
> Hi Joelle,
>
> All the HCP subjects are considered healthy young adults with no diagnosed
> cognitive abnormalities. They do, of course, have a range of abilities and
> scores on the behavioral tests we conduct.
>
>
>
> There is a lot of information in Chapter 1 of the current 500 Subjects
> Reference Manual
> <http://humanconnectome.org/documentation/S500/HCP_S500+MEG2_Release_Reference_Manual.pdf>
> for navigating the behavioral data and for filtering subjects—please check
> it out. There is also a  “Download CSV button” at the upper right of the
> subject Dashboard that will allow you to download all the open access
> behavioral data in one spreadsheet. Look at the sections of the Reference
> Manual on Restricted access data to see if you need to apply for access to
> that data for your purposes.
>
>
>
> As detailed in the Introduction 

Re: [HCP-Users] Demographic and behavioral subject data

[Jennifer Elam]

Hi Joelle,

The r227 is the newer, improved version. On the HCP Issues wiki 
<https://wiki.humanconnectome.org/pages/viewpage.action?pageId=29589520> :

 

Image reconstruction algorithm versions 
Two versions of the image reconstruction algorithm applied to dMRI and fMRI 
data have been used in HCP to date: version r177 for subjects scanned in Q1 
through mid-Q3, version r227 for subjects scanned mid-Q3 and after.  We were 
able to retroactively recon all dMRI data using the newer r227 version. 
However, for the fMRI data, this was not possible and data reconstructed with 
both r177 and r227 versions remain in ConnectomeDB. The reconstruction version 
makes a notable signature on the data that can make a large difference in fMRI 
data analysis. Users wanting to use only data with the same reconstruction 
algorithm applied in their analyses can filter data on the ConnectomeDB 
dashboard by fMRI reconstruction version (in the Study Completion category). 
See Ramifications of Image Reconstruction Version Differences 
<https://wiki.humanconnectome.org/x/RQBJB>  for more details.

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: Joelle Zimmermann [mailto:joelle.t.zimmerm...@gmail.com] 
Sent: Monday, November 30, 2015 4:54 PM
To: Jennifer Elam
Cc: hcp-users@humanconnectome.org
Subject: Re: [HCP-Users] Demographic and behavioral subject data

 

Hi Jennifer,

 

Thanks a lot for your help, that's really useful.

 

With regard to the reconstruction - I just wanted to clarify, and apologies if 
this is in the manual but I did not find it - When I filter by 'Study 
Completion' > 'Image Reconstruction' > 3T MR fMRI recon, I have 2 options - 
r177 and r227. 

 

Which is the more recent/ considered 'better' reconstruction method?

 

I suspect that the r227 is better if I am interested in using both diffusion 
MRI data and fMRI data, as the r227 is available for both, whereas r177 is only 
available for fMRI data, and not for dMRI. Is that correct?

 

Thanks,

Joelle

 

On Mon, Nov 30, 2015 at 1:48 PM, Jennifer Elam <el...@pcg.wustl.edu> wrote:

Hi Joelle,

 

Here are the HCP Inclusion Criteria:

Inclusion Criteria:

No significant history of psychiatric disorder, substance abuse, neurological, 
or cardiovascular disease

-No person report of diagnosis by a treating physician

-No hospitalization

No pharmacologic or behavioral treatment (12 months duration or longer) by a 
specialty-trained physician (psychiatrist, neurologist, cardiologist) or 
therapist (e.g., psychologist, social worker)

-Childhood ADHD with no current treatment is allowed

-Transient childhood seizures allowed (clarify what type)

-Migraines allowed if not taking daily psychoactive medications

Age 22 to 35

Ability to give valid informed consent

MMSE score of 24 or above

 

Here are the HCP Exclusion Criteria:

Two or more non-provoked (e.g., not due to fever) seizures or a diagnosis of 
epilepsy

Any genetic disorder, such as Cystic Fibrosis 

Use of daily prescription medications for migraines in the past month

Multiple Sclerosis, Cerebral Palsy

Brain tumor or Stroke

Currently on chemotherapy or immunomodulatory agents, or history of radiation 
or chemotherapy that could affect the brain

Sickle Cell Disease

Thyroid Hormone Treatment in the past month

Treatment for Diabetes in the past month (do not exclude for gestational or 
diet controlled diabetes)

Head Injury If:

  LOC>30 minutes or Amnesia >24 hours

  Change in Mental Status >24 hours or CT findings consistent with TBI

  3 or more concussive (mild) TBIs

Premature Birth (Born >37 weeks for non-twins, born <34 weeks for twins. If 
weeks unknown, less than 5 lbs. at birth for non-twins.

Current Pregnancy

Unsafe metal or devices in the body (Cardiac Pacemaker, cochlear implant, 
aneurism clip)

Moderate to Severe Claustrophobia

 

Hope that helps.

 

Best,

Jenn

 

Jennifer Elam, Ph.D.
Outreach Coordinator, Human Connectome Project
Washington University School of Medicine
Department of Anatomy and Neurobiology, Box 8108
660 South Euclid Avenue
St. Louis, MO 63110
314-362-9387
el...@pcg.wustl.edu
www.humanconnectome.org

 

From: Joelle Zimmermann [mailto:joelle.t.zimmerm...@gmail.com] 
Sent: Monday, November 30, 2015 11:12 AM
To: Jennifer Elam
Cc: hcp-users@humanconnectome.org
Subject: Re: [HCP-Users] Demographic and behavioral subject data

 

Hi Michael and Jennifer,

 

Thank you both for your help, much appreciated. One remaining question - is 
there currently any cutoff for cognitive scores (i.e. for the MMSE for ex) for 
subjects being included in the 500 release dataset?  Can't find mention of it 
in