[NMusers] Time to event analysis using NONMEM

2009-06-09 Thread Anubha_Gupta
Dear NMUsers I am trying to analyse time to single event data using NONMEM VI. I am getting the following termination message. If some body could point out what I am doing wrong or may be elaborate on the error message that would be very helpful. Thanks in advance Anubha 0PROGRAM TERMINATED

RE: [NMusers] Time to event analysis using NONMEM

2009-06-09 Thread Mats Karlsson
4714105 fax: +46 18 471 4003 From: owner-nmus...@globomaxnm.com [mailto:owner-nmus...@globomaxnm.com] On Behalf Of anubha_gu...@eisai.net Sent: Tuesday, June 09, 2009 5:24 PM To: nmusers@globomaxnm.com Subject: [NMusers] Time to event analysis using NONMEM Dear NMUsers I am trying

Re: [NMusers] Time to event analysis using NONMEM

2009-06-09 Thread Nick Holford
Anubha, You need to have a zero time record for each observation. NONMEM needs to integrate the hazard from time 0 upto the time of the event. You should also have CS=DV and use MDV=1 for the TIME zero record and MDV=0 for the event observation. The event 'observation' is either 1