Can anybody explain why RMA has to have a default normalization method:
quantile-quantile? Why don't leave the choices to users?
If I just want to use RMA to do a background correction without
normalization, how should I specify the ? in the normalize.method=? ?
Hairong
1. This question is more appropriate for the BioConductor mailing list.
2. Any Affymetrix pre-processing can be split into background
correction, normalisation and summary stages. The combination of rma
background, quantile normalisation and median polish summary gives rise
to RMA. Therefore
Hairong Wei wrote:
Can anybody explain why RMA has to have a default normalization method:
quantile-quantile? Why don't leave the choices to users?
If I just want to use RMA to do a background correction without
normalization, how should I specify the ? in the normalize.method=? ?
What is RMA?
