I have the same problem using Ubuntu 8.10. I ran winedbg and noticed
that it is trying to connected to the Pulse Audio server and timing out.
Could this be what is causing the problem?
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On Feisty Linux, Wine is very slow at starting up
https://bugs.launchpad.net/bugs/83475
You received this
I have just switched from pulseaudio to ALSA using this tutorial
http://idyllictux.wordpress.com/2008/10/29/alsa-instead-of-pulseaudio-
for-ubuntu-810-intrepid-a-non-destructive-way/ and now wine applications
are starting up as they should be. In my case the wine applications
were waiting for the